Role of ubiquitin-mediated proteolysis in the pathogenesis of neurodegenerative disorders. (Q35548597)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

review article

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title

Role of ubiquitin-mediated proteolysis in the pathogenesis of neurodegenerative disorders (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

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1

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19 December 2019

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James R Cavey

2

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19 December 2019

James Lowe

series ordinal

3

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19 December 2019

language of work or name

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1 October 2003

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19 December 2019

published in

Ageing Research Reviews

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19 December 2019

volume

2

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19 December 2019

issue

4

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19 December 2019

page(s)

343-356

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Ubiquitin: not just for proteasomes anymore

19 December 2019

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7 January 2021

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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7 January 2021

Multicatalytic proteinase is present in Lewy bodies and neurofibrillary tangles in diffuse Lewy body disease brains.

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7 January 2021

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

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7 January 2021

A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons

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7 January 2021

Proteasomal function is impaired in substantia nigra in Parkinson's disease

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7 January 2021

Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease

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7 January 2021

Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures

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7 January 2021

Altered proteasomal function in sporadic Parkinson's disease

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7 January 2021

Ubiquitin is a component of paired helical filaments in Alzheimer's disease.

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7 January 2021

Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments

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7 January 2021

How the ubiquitin-proteasome system controls transcription

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7 January 2021

Proteins are unfolded on the surface of the ATPase ring before transport into the proteasome

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7 January 2021

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

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7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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7 January 2021

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7 January 2021

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7 January 2021

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

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7 January 2021

Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

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7 January 2021

A ubiquitin mutant with specific defects in DNA repair and multiubiquitination

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7 January 2021

Alpha-synuclein in Lewy bodies

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7 January 2021

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.

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7 January 2021

Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity

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7 January 2021

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

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7 January 2021

Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein

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7 January 2021

Recognition of the polyubiquitin proteolytic signal

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7 January 2021

alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome

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7 January 2021

Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function.

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7 January 2021

Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations.

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7 January 2021

Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

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7 January 2021

+1 Proteins and aging

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7 January 2021

Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome

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7 January 2021

Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease

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7 January 2021

Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila

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7 January 2021

10.1016/S1568-1637(03)00025-4

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14522239%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

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