mTOR as a Positive Regulator of Tumor Cell Responses to Hypoxia (Q35560399)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14560965%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

review article

1 reference

title

mTOR as a positive regulator of tumor cell responses to hypoxia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14560965%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

mTOR as a Positive Regulator of Tumor Cell Responses to Hypoxia (English)

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

21 March 2024

1 reference

R. T. Abraham

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14560965

21 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14560965

21 March 2024

publication date

1 January 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14560965%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

20 December 2019

https://link.springer.com/content/pdf/10.1007/978-3-642-18930-2_18

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Current Topics in Microbiology and Immunology

21 March 2024

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14560965%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14560965%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

page(s)

299-319

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14560965%20AND%20SRC:MED&resulttype=core&format=json

Cell cycle checkpoint signaling through the ATM and ATR kinases

20 December 2019

cites work

1

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Immunopharmacology of rapamycin

21 March 2024

2

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 March 2024

3

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

21 March 2024

4

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Ten years of protein kinase B signalling: a hard Akt to follow

21 March 2024

5

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

21 March 2024

6

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

A conserved family of prolyl-4-hydroxylases that modify HIF

21 March 2024

7

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus

21 March 2024

8

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

21 March 2024

9

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 March 2024

11

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Cloning of a novel phosphatidylinositol kinase-related kinase: characterization of the human SMG-1 RNA surveillance protein

21 March 2024

12

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction

21 March 2024

13

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha

21 March 2024

14

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 March 2024

15

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes

21 March 2024

16

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

21 March 2024

Phosphoinositide kinases

17

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

21 March 2024

18

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Regulation of translation initiation by FRAP/mTOR

21 March 2024

19

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

21 March 2024

20

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor

21 March 2024

21

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

21 March 2024

22

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

21 March 2024

23

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Studies on the mechanism of resistance to rapamycin in human cancer cells

21 March 2024

24

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

21 March 2024

25

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

When is a lipid kinase not a lipid kinase? When it is a protein kinase

21 March 2024

26

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Mitogen-activated protein kinase kinase inhibitor PD98059 blocks the trans-activation but not the stabilization or DNA binding ability of hypoxia-inducible factor-1alpha

21 March 2024

27

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Amino acid-dependent control of p70(s6k). Involvement of tRNA aminoacylation in the regulation

21 March 2024

28

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 March 2024

29

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

21 March 2024

31

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

21 March 2024

32

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Cytoplasmic-nuclear shuttling of FKBP12-rapamycin-associated protein is involved in rapamycin-sensitive signaling and translation initiation

21 March 2024

33

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

The von Hippel-Lindau tumor suppressor gene

21 March 2024

34

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

21 March 2024

35

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

21 March 2024

36

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

21 March 2024

37

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

PTEN: a tumour suppressor that functions as a phospholipid phosphatase

21 March 2024

38

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

PTEN and myotubularin: novel phosphoinositide phosphatases

21 March 2024

39

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

21 March 2024

40

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins

21 March 2024

42

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Linking molecular therapeutics to molecular diagnostics: inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo

21 March 2024

43

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Drosophila S6 kinase: a regulator of cell size

21 March 2024

44

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression

21 March 2024

45

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

21 March 2024

46

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

21 March 2024

47

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

21 March 2024

48

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

21 March 2024

49

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

21 March 2024

50

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

The TOR kinases link nutrient sensing to cell growth

21 March 2024

51

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

21 March 2024

52

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

21 March 2024

53

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

TOR, a central controller of cell growth

21 March 2024

54

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

21 March 2024

55

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

21 March 2024

57

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus

21 March 2024

59

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells

21 March 2024

60

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

PTEN: life as a tumor suppressor

21 March 2024

61

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

The DNA-dependent protein kinase

21 March 2024

62

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Genetic control of cell size

21 March 2024

64

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

A role for ATR in the DNA damage-induced phosphorylation of p53

21 March 2024

66

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

c-Myc regulates mammalian body size by controlling cell number but not cell size.

21 March 2024

67

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase

21 March 2024

68

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

21 March 2024

69

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_18

21 March 2024

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14560965%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference