C-reactive protein and cardiovascular disease: new insights from an old molecule (Q35562701)

8 August 2017

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title

C-reactive protein and cardiovascular disease: new insights from an old molecule (English)

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8 August 2017

cardiovascular disease

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2

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8 August 2017

Hirschfield GM

1

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PubMed ID

14566035

8 August 2017

language of work or name

English

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publication date

1 November 2003

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QJM: An International Journal of Medicine

8 August 2017

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8 August 2017

96

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8 August 2017

793-807

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8 August 2017

11

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Acute-phase proteins and other systemic responses to inflammation

8 August 2017

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https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Atherosclerosis — An Inflammatory Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Inflammation and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

SEROLOGICAL REACTIONS IN PNEUMONIA WITH A NON-PROTEIN SOMATIC FRACTION OF PNEUMOCOCCUS

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Control of the acute phase response. Serum C-reactive protein kinetics after acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

The pentraxins, C-reactive protein and serum amyloid P component, are cleared and catabolized by hepatocytes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Serum C-reactive protein levels in the management of infection in acute leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Characterization of C-reactive protein and the complement subcomponent C1t as homologous proteins displaying cyclic pentameric symmetry (pentraxins)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Amyloid P component. A critical review

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Serum amyloid P-component is an acute-phase reactant in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Interaction of C-reactive protein with artificial phosphatidylcholine bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Binding of pentraxins to different nuclear structures: C-reactive protein binds to small nuclear ribonucleoprotein particles, serum amyloid P component binds to chromatin and nucleoli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an antiinflammatory innate immune response: implications for systemic autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Function of C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Interactions of C-reactive protein with the complement system. I. Protamine-induced consumption of complement in acute phase sera

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Regulation of complement activation by C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Innate immune recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

The role of complement in the acquired immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein is protective against Streptococcus pneumoniae infection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Phosphorylcholine on the lipopolysaccharide of Haemophilus influenzae contributes to persistence in the respiratory tract and sensitivity to serum killing mediated by C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

The position of phosphorylcholine on the lipopolysaccharide of Haemophilus influenzae affects binding and sensitivity to C-reactive protein-mediated killing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Low density lipoprotein and very low density lipoprotein are selectively bound by aggregated C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

The physiological structure of human C-reactive protein and its complex with phosphocholine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Three dimensional structure of human C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Isolation of human C-reactive protein complementary DNA and localization of the gene to chromosome 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

The liver as the site of C-reactive protein formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Extrahepatic transcription of human C-reactive protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Human neurons generate C-reactive protein and amyloid P: upregulation in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Expression of C-reactive protein in the human respiratory tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Generation of C-reactive protein and complement components in atherosclerotic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

The inhibitory effect of C-reactive protein on bacterial phosphorylcholine platelet-activating factor receptor-mediated adherence is blocked by surfactant

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Identification of a C-reactive protein binding site in two hepatic carboxylesterases capable of retaining C-reactive protein within the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Familial and genetic determinants of systemic markers of inflammation: the NHLBI family heart study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Genotype at a promoter polymorphism of the interleukin-6 gene is associated with baseline levels of plasma C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Polymorphism in the human C-reactive protein (CRP) gene, plasma concentrations of CRP, and the risk of future arterial thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Association between baseline levels of C-reactive protein (CRP) and a dinucleotide repeat polymorphism in the intron of the CRP gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Research pointers: Association of common genetic variant with susceptibility to invasive pneumococcal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Production of C-reactive protein and risk of coronary events in stable and unstable angina. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-Reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein as a cardiovascular risk factor: more than an epiphenomenon?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Studies of acute-phase protein. II. Localization of Cx-reactive protein in heart in induced myocardial infarction in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein and complement are important mediators of tissue damage in acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Elevated levels of C-reactive protein at discharge in patients with unstable angina predict recurrent instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein and outcome after ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein in ischemic stroke: an independent prognostic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Prognostic relevance of early serial C-reactive protein measurements after first ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

End-stage renal disease, atherosclerosis, and cardiovascular mortality: is C-reactive protein the missing link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein is not associated with the presence or extent of calcified subclinical atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein is associated with subclinical epicardial coronary calcification in men and women: the Framingham Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Widespread coronary inflammation in unstable angina

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Predictive value of C-reactive protein and troponin T in patients with unstable angina: a comparative analysis. CAPTURE Investigators. Chimeric c7E3 AntiPlatelet Therapy in Unstable angina REfractory to standard treatment trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Association between C-reactive protein and features of the metabolic syndrome: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14 719 initially healthy American women

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Body mass index, diabetes, and C-reactive protein among U.S. adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Differentiation between obesity and insulin resistance in the association with C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Effect of postmenopausal hormones on inflammation-sensitive proteins: the Postmenopausal Estrogen/Progestin Interventions (PEPI) Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Hormone replacement therapy and increased plasma concentration of C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Effect of transdermal estradiol and oral conjugated estrogen on C-reactive protein in retinoid-placebo trial in healthy women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein and paroxysmal atrial fibrillation: evidence of the implication of an inflammatory process in paroxysmal atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Energy restriction and weight loss on very-low-fat diets reduce C-reactive protein concentrations in obese, healthy women

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Weight loss reduces C-reactive protein levels in obese postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Effect of alcohol consumption on systemic markers of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Alcohol consumption and plasma concentration of C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Does exercise reduce inflammation? Physical activity and C-reactive protein among U.S. adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Associations between cardiorespiratory fitness and C-reactive protein in men

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Effect of hydroxymethyl glutaryl coenzyme a reductase inhibitor therapy on high sensitive C-reactive protein levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Rapid reduction in C-reactive protein with cerivastatin among 785 patients with primary hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Simvastatin lowers C-reactive protein within 14 days: an effect independent of low-density lipoprotein cholesterol reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Statins and the acute-phase response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFkappa B-C/EBP-beta complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Markers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Influence of C3 deficiency on atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Interferon-gamma and lipopolysaccharide potentiate monocyte tissue factor induction by C-reactive protein: relationship with age, sex, and hormone replacement treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

The major receptor for C-reactive protein on leukocytes is fcgamma receptor II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein binding to FcgammaRIIa on human monocytes and neutrophils is allele-specific

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein-mediated phagocytosis and phospholipase D signalling through the high-affinity receptor for immunoglobulin G (FcgammaRI).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Lack of specific receptors for C-reactive protein on white blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Human C-reactive protein does not bind to FcgammaRIIa on phagocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Acute systemic inflammation impairs endothelium-dependent dilatation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-Reactive protein augments inducible nitric oxide synthase expression in cytokine-stimulated cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Modulation of C-reactive protein-mediated monocyte chemoattractant protein-1 induction in human endothelial cells by anti-atherosclerosis drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells: implications for the metabolic syndrome and atherothrombosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

C-reactive protein-mediated low density lipoprotein uptake by macrophages: implications for atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

The phlogistic role of C3 leukotactic fragments in myocardial infarcts of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Reduction by Cobra Venom Factor of Myocardial Necrosis after Coronary Artery Occlusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Complement localization and mediation of ischemic injury in baboon myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

CRP, a major culprit in complement-mediated tissue damage in acute myocardial infarction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Incremental prognostic value of serum levels of troponin T and C-reactive protein on admission in patients with unstable angina pectoris

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

Preprocedural serum levels of C-reactive protein predict early complications and late restenosis after coronary angioplasty

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCG134

21 January 2018

Identifiers

DOI

10.1093/QJMED/HCG134

1 reference

8 August 2017

1 reference

PubMed ID

14566035