Sorafenib potently inhibits papillary thyroid carcinomas harboring RET/PTC1 rearrangement (Q35570953)

8 August 2017

title

Sorafenib potently inhibits papillary thyroid carcinomas harboring RET/PTC1 rearrangement (English)

1 reference

8 August 2017

Ying C Henderson

1

1 reference

8 August 2017

Soon-Hyun Ahn

series ordinal

2

1 reference

8 August 2017

Ya'an Kang

series ordinal

3

1 reference

8 August 2017

Gary L Clayman

series ordinal

4

1 reference

8 August 2017

language of work or name

English

0 references

publication date

1 August 2008

1 reference

8 August 2017

published in

Clinical Cancer Research

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8 August 2017

volume

14

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8 August 2017

issue

15

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8 August 2017

page(s)

4908-4914

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An orthotopic model of papillary thyroid carcinoma in athymic nude mice

8 August 2017

cites work

1 reference

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Differential responses of human papillary thyroid cancer cell lines carrying the RET/PTC1 rearrangement or a BRAF mutation to MEK1/2 inhibitors

12 July 2018

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Sorafenib in advanced clear-cell renal-cell carcinoma

12 July 2018

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Raf kinases: oncogenesis and drug discovery

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12 July 2018

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BAY 43-9006 inhibition of oncogenic RET mutants

12 July 2018

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The Raf inhibitor BAY 43-9006 (Sorafenib) induces caspase-independent apoptosis in melanoma cells

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12 July 2018

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The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

12 July 2018

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12 July 2018

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The RAF proteins take centre stage

12 July 2018

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

12 July 2018

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12 July 2018

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12 July 2018

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Mutations of the BRAF gene in human cancer

12 July 2018

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Growth inhibition of new human thyroid carcinoma cell lines by activation of adenylate cyclase through the beta-adrenergic receptor

12 July 2018

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Antitumor actions of cytokines on new human papillary thyroid carcinoma cell lines

12 July 2018

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Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma

12 July 2018

1 reference

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The ret/PTC oncogene in papillary thyroid carcinoma

12 July 2018

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Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI alpha of cyclic AMP-dependent protein kinase A

12 July 2018

1 reference

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PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

12 July 2018

1 reference

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BRAF is a therapeutic target in aggressive thyroid carcinoma.

12 July 2018

1 reference

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Clinical trials referral resource. Current clinical trials of BAY 43-9006, Part 1.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4420193

Clinical trials referral resource

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18676765

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18676765

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1078-0432.CCR-07-1772

1 reference

8 August 2017

1 reference

8 August 2017

1 reference