Promoting motions in enzyme catalysis probed by pressure studies of kinetic isotope effects (Q35578715)

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23 December 2019

title

Promoting motions in enzyme catalysis probed by pressure studies of kinetic isotope effects (English)

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23 December 2019

1

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23 December 2019

Mike Sutcliffe

series ordinal

2

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23 December 2019

3

Nigel S Scrutton

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23 December 2019

language of work or name

English

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publication date

3 January 2007

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23 December 2019

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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23 December 2019

volume

104

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23 December 2019

issue

2

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23 December 2019

page(s)

507-512

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An analysis of reaction pathways for proton tunnelling in methylamine dehydrogenase

23 December 2019

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1 reference

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Unusual origins of isotope effects in enzyme-catalysed reactions

12 July 2018

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Small temperature dependence of the kinetic isotope effect for the hydride transfer reaction catalyzed by Escherichia coli dihydrofolate reductase

12 July 2018

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Atomic description of an enzyme reaction dominated by proton tunneling

12 July 2018

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Hydrogen tunneling in quinoproteins.

12 July 2018

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12 July 2018

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12 July 2018

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The rate of hydrolysis of phosphomonoester dianions and the exceptional catalytic proficiencies of protein and inositol phosphatases

12 July 2018

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Environmentally coupled hydrogen tunneling. Linking catalysis to dynamics

12 July 2018

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Effect of pressure on electron transfer reactions in inorganic and bioinorganic chemistry

12 July 2018

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Effects of high pressure on enzymatic activity

12 July 2018

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Temperature-dependent isotope effects in soybean lipoxygenase-1: correlating hydrogen tunneling with protein dynamics.

12 July 2018

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Network of coupled promoting motions in enzyme catalysis

12 July 2018

1 reference

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Effect of pressure on deuterium isotope effects of formate dehydrogenase

12 July 2018

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Enzymatic H-transfer requires vibration-driven extreme tunneling

12 July 2018

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High pressure effects on protein structure and function

12 July 2018

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Old yellow enzyme at 2 A resolution: overall structure, ligand binding, and comparison with related flavoproteins

12 July 2018

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Crystal structure of hen egg-white lysozyme at a hydrostatic pressure of 1000 atmospheres

12 July 2018

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Vibrationally enhanced tunneling as a mechanism for enzymatic hydrogen transfer

12 July 2018

1 reference

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Stereoselective preparation of deuterated reduced nicotinamide adenine nucleotides and substrates by enzymatic synthesis

12 July 2018

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The low barrier hydrogen bond in enzymatic catalysis.

12 July 2018

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Electrostatic origin of the catalytic power of enzymes and the role of preorganized active sites

21 January 2018

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Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase.

21 January 2018

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Importance of barrier shape in enzyme-catalyzed reactions. Vibrationally assisted hydrogen tunneling in tryptophan tryptophylquinone-dependent amine dehydrogenases

21 January 2018

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Hydrogen tunneling in peptidylglycine alpha-hydroxylating monooxygenase

21 January 2018

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H-tunneling in the multiple H-transfers of the catalytic cycle of morphinone reductase and in the reductive half-reaction of the homologous pentaerythritol tetranitrate reductase.

21 January 2018

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Evidence for environmentally coupled hydrogen tunneling during dihydrofolate reductase catalysis

21 January 2018

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Vibrationally enhanced hydrogen tunneling in the Escherichia coli thymidylate synthase catalyzed reaction

21 January 2018

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Tunneling and coupled motion in the Escherichia coli dihydrofolate reductase catalysis

21 January 2018

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Coupling of protein motions and hydrogen transfer during catalysis by Escherichia coli dihydrofolate reductase

21 January 2018

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Hydride transfer reaction catalyzed by hyperthermophilic dihydrofolate reductase is dominated by quantum mechanical tunneling and is promoted by both inter- and intramonomeric correlated motions.

21 January 2018

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Electron transfers in chemistry and biology

21 January 2018

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Effect of pressure on deuterium isotope effects of yeast alcohol dehydrogenase: evidence for mechanical models of catalysis.

21 January 2018

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Ensemble-averaged variational transition state theory with optimized multidimensional tunneling for enzyme kinetics and other condensed-phase reactions

21 January 2018

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Quantum mechanical tunneling in methylamine dehydrogenase

21 January 2018

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Erratum to: “Quantum mechanical tunneling in methylamine dehydrogenase” [Chem. Phys. Lett. 347 (2001) 512–518]

21 January 2018

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α-Secondary Isotope Effects as Probes of “Tunneling-Ready” Configurations in Enzymatic H-Tunneling: Insight from Environmentally Coupled Tunneling Models

21 January 2018

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Reductive and oxidative half-reactions of morphinone reductase from Pseudomonas putida M10: a kinetic and thermodynamic analysis

21 January 2018

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12 December 2020

Enzyme catalytic power minireview series

1 reference

12 December 2020

Solvation, reorganization energy, and biological catalysis

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12 December 2020

Kinetic studies of the mechanism of carbon-hydrogen bond breakage by the heterotetrameric sarcosine oxidase of Arthrobacter sp. 1-IN

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12 December 2020

QM/MM studies show substantial tunneling for the hydrogen-transfer reaction in methylamine dehydrogenase

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0608408104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17202258%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

0 references

1 reference

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23 December 2019

PubMed publication ID

17202258

1 reference