Phosphorylation of PCNA by EGFR inhibits mismatch repair and promotes misincorporation during DNA synthesis (Q35590357)

9 August 2017

title

Phosphorylation of PCNA by EGFR inhibits mismatch repair and promotes misincorporation during DNA synthesis (English)

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9 August 2017

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1 reference

Guo-Min Li

6

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author name string

Janice Ortega

1

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9 August 2017

Jessie Y Li

2

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9 August 2017

Sanghee Lee

3

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9 August 2017

Dan Tong

4

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9 August 2017

Liya Gu

5

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9 August 2017

language of work or name

English

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publication date

30 March 2015

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Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

number of pages

6

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based on heuristic

inferred from page(s)

published in

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9 August 2017

volume

112

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9 August 2017

issue

18

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9 August 2017

page(s)

5667-5672

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PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair.

9 August 2017

cites work

1 reference

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Reconstitution of long and short patch mismatch repair reactions using Saccharomyces cerevisiae proteins

12 July 2018

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The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα

12 July 2018

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Regulation of PCNA-protein interactions for genome stability

12 July 2018

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Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

12 July 2018

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DNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions in Saccharomyces cerevisiae.

12 July 2018

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Ubiquitin-family modifications in the replication of DNA damage

12 July 2018

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Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth.

12 July 2018

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An A13 repeat within the 3'-untranslated region of epidermal growth factor receptor (EGFR) is frequently mutated in microsatellite instability colon cancers and is associated with increased EGFR expression

12 July 2018

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Mechanisms and functions of DNA mismatch repair

12 July 2018

1 reference

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PCNA, the maestro of the replication fork

12 July 2018

1 reference

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Tyrosine phosphorylation controls PCNA function through protein stability

12 July 2018

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Reconstitution of 5'-directed human mismatch repair in a purified system

12 July 2018

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12 July 2018

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Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design

12 July 2018

1 reference

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Role of DNA mismatch repair defects in the pathogenesis of human cancer

12 July 2018

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Partial reconstitution of human DNA mismatch repair in vitro: characterization of the role of human replication protein A

12 July 2018

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EGFR and cancer prognosis

12 July 2018

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Nuclear localization of EGF receptor and its potential new role as a transcription factor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes

12 July 2018

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Studies on the interactions between human replication factor C and human proliferating cell nuclear antigen

12 July 2018

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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

12 July 2018

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ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Biochemistry and genetics of eukaryotic mismatch repair

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Identification of mismatch repair genes and their role in the development of cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

12 July 2018

Epidermal Growth Factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Endonucleolytic function of MutLalpha in human mismatch repair.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Differential requirement for proliferating cell nuclear antigen in 5' and 3' nick-directed excision in human mismatch repair

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Transfer of the MSH2.MSH6 complex from proliferating cell nuclear antigen to mispaired bases in DNA.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426468

Analysis of interactions between mismatch repair initiation factors and the replication processivity factor PCNA

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25825764

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1417711112

1 reference

9 August 2017

0 references

1 reference

9 August 2017

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