Dendritic-cell control of pathogen-driven T-cell polarization (Q35597117)

9 August 2017

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title

Dendritic-cell control of pathogen-driven T-cell polarization (English)

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9 August 2017

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Martien L Kapsenberg

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9 August 2017

1 December 2003

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Nature Reviews Immunology

9 August 2017

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9 August 2017

3

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9 August 2017

984-993

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9 August 2017

12

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Natural versus adaptive regulatory T cells

9 August 2017

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Dendritic cells and the control of immunity

31 March 2020

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Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skin

31 March 2020

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The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand

31 March 2020

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T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal

31 March 2020

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Natural interferon alpha/beta-producing cells link innate and adaptive immunity

31 March 2020

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Cytokines regulate the capacity of CD8alpha(+) and CD8alpha(-) dendritic cells to prime Th1/Th2 cells in vivo

31 March 2020

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A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization

31 March 2020

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Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering

31 March 2020

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A Simple, Conservative Explanation of the H-2 Restriction of Interactions Between Lymphocytes

31 March 2020

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Interleukin-12 and the regulation of innate resistance and adaptive immunity

31 March 2020

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Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells

31 March 2020

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Conditioning of dendritic cells by pathogen-derived stimuli.

31 March 2020

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High-level IL-12 production by human dendritic cells requires two signals

31 March 2020

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CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

31 March 2020

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CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal

31 March 2020

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Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12

31 March 2020

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CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaB

31 March 2020

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Approaching the asymptote? Evolution and revolution in immunology

31 March 2020

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Innate immune recognition

31 March 2020

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Toll-like receptors: critical proteins linking innate and acquired immunity

31 March 2020

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Toll-like receptors control activation of adaptive immune responses

31 March 2020

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Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses.

31 March 2020

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An innate sense of danger

31 March 2020

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Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells

31 March 2020

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Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors

31 March 2020

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Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

31 March 2020

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Cutting edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway

31 March 2020

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Discrimination of bacterial lipoproteins by Toll-like receptor 6

31 March 2020

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CTL-mediated killing of intracellular Mycobacterium tuberculosis is independent of target cell nuclear apoptosis

31 March 2020

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Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells

31 March 2020

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Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present

31 March 2020

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The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

31 March 2020

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Synthetic mycoplasma-derived lipopeptide MALP-2 induces maturation and function of dendritic cells.

31 March 2020

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Differential induction of interleukin-10 and interleukin-12 in dendritic cells by microbial toll-like receptor activators and skewing of T-cell cytokine profiles.

31 March 2020

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Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2.

31 March 2020

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The C-type lectin DC-SIGN (CD209) is an antigen-uptake receptor for Candida albicans on dendritic cells

31 March 2020

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Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression

31 March 2020

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

31 March 2020

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Maturation, activation, and protection of dendritic cells induced by double-stranded RNA

31 March 2020

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Microbial Compounds Selectively Induce Th1 Cell-Promoting or Th2 Cell-Promoting Dendritic Cells In Vitro with Diverse Th Cell-Polarizing Signals

31 March 2020

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Intercellular Adhesion Molecule-1/LFA-1 Ligation Favors Human Th1 Development

31 March 2020

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Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation

31 March 2020

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Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen

31 March 2020

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Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo

31 March 2020

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Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway

31 March 2020

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Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines.

31 March 2020

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Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets

31 March 2020

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Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

31 March 2020

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Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7

31 March 2020

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Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

31 March 2020

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A Toll-like receptor recognizes bacterial DNA

31 March 2020

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

31 March 2020

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Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

31 March 2020

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The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

31 March 2020

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The other side of the coin: the protective role of the TH2 cytokines.

31 March 2020

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A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drives development of Th2 cells

31 March 2020

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Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni

31 March 2020

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CD8- dendritic cell activation status plays an integral role in influencing Th2 response development

31 March 2020

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Lacto-N-fucopentaose III found on Schistosoma mansoni egg antigens functions as adjuvant for proteins by inducing Th2-type response

31 March 2020

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Endotoxin can induce MyD88-deficient dendritic cells to support T(h)2 cell differentiation

31 March 2020

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A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

31 March 2020

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CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

31 March 2020

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B7/CD28-Dependent CD4+CD25+ Regulatory T Cells Are Essential Components of the Memory-Protective Immunity to Candida albicans

31 March 2020

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Malaria, monocytes, macrophages and myeloid dendritic cells: sticking of infected erythrocytes switches off host cells

31 March 2020

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DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells

31 March 2020

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Mycobacteria target DC-SIGN to suppress dendritic cell function

31 March 2020

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Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation.

31 March 2020

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Human cytomegalovirus inhibits maturation and impairs function of monocyte-derived dendritic cells

31 March 2020

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Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussi

31 March 2020

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Evasion of innate immunity by parasitic protozoa

31 March 2020

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How dendritic cells and microbes interact to elicit or subvert protective immune responses

31 March 2020

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Immune escape through C-type lectins on dendritic cells

31 March 2020

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IRF3 mediates a TLR3/TLR4-specific antiviral gene program

31 March 2020

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IL-12 and IFN-gamma in host defense against mycobacteria and salmonella in mice and men.

31 March 2020

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Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

31 March 2020

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Helper T cells regulate type-2 innate immunity in vivo

31 March 2020

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Analysis of immunomodulatory activities of aqueous humor from eyes of mice with experimental autoimmune uveitis

31 March 2020

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CCR5 provides a signal for microbial induced production of IL-12 by CD8α+ dendritic cells

31 March 2020

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Development of Th1-inducing capacity in myeloid dendritic cells requires environmental instruction

31 March 2020

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Double-stranded RNA-exposed human keratinocytes promote Th1 responses by inducing a Type-1 polarized phenotype in dendritic cells: role of keratinocyte-derived tumor necrosis factor alpha, type I interferons, and interleukin-18

31 March 2020

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Histamine polarizes human dendritic cells into Th2 cell-promoting effector dendritic cells

31 March 2020

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Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP.

31 March 2020

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Selective suppression of IL-12 production by chemoattractants

31 March 2020

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Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse

31 March 2020

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Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation

31 March 2020

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The role of dendritic cells, B cells, and M cells in gut-oriented immune responses.

31 March 2020

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Unique functions of CD11b+, CD8 alpha+, and double-negative Peyer's patch dendritic cells

31 March 2020

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Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen

31 March 2020

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CD8alpha+ and CD8alpha- subclasses of dendritic cells direct the development of distinct T helper cells in vivo

31 March 2020

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Distinct dendritic cell subsets differentially regulate the class of immune response in vivo

31 March 2020

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Reciprocal control of T helper cell and dendritic cell differentiation

31 March 2020

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The ability of murine dendritic cell subsets to direct T helper cell differentiation is dependent on microbial signals

31 March 2020

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On the role of dendritic cells in peripheral T cell tolerance and modulation of autoimmunity

31 March 2020

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Characterization of Dendritic Cells that Induce Tolerance and T Regulatory 1 Cell Differentiation In Vivo

31 March 2020

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Mucosal CD8alpha+ DC, with a plasmacytoid phenotype, induce differentiation and support function of T cells with regulatory properties

31 March 2020

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The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

31 March 2020

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Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

31 March 2020

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Maturation of human monocyte-derived dendritic cells studied by microarray hybridization

31 March 2020

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The plasticity of dendritic cell responses to pathogens and their components

31 March 2020

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Transcriptional reprogramming of dendritic cells by differentiation stimuli

31 March 2020

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Cell-type and donor-specific transcriptional responses to interferon-alpha. Use of customized gene arrays.

31 March 2020

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CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen

31 March 2020

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Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology

31 March 2020

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The dendritic cell populations of mouse lymph nodes.

31 March 2020

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Characterization of human blood dendritic cell subsets

31 March 2020

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

31 March 2020

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Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells

31 March 2020

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IFN-alpha enhances CD40 ligand-mediated activation of immature monocyte-derived dendritic cells.

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI1246

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9 August 2017

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PubMed ID

14647480