Drug Repurposing Screen Identifies Foxo1-Dependent Angiopoietin-2 Regulation in Sepsis. (Q35597977)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25855898%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Drug Repurposing Screen Identifies Foxo1-Dependent Angiopoietin-2 Regulation in Sepsis (English)

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5 March 2020

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12

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5 March 2020

Keqing Wang

13

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15

Michael W Donnino

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5 March 2020

author name string

Chandra C Ghosh

1

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5 March 2020

Kristina Thamm

2

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5 March 2020

Anthony V Berghelli

3

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Claudia Schrimpf

4

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Manish R Maski

5

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5 March 2020

Tanaz Abid

6

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5 March 2020

Katelyn E Milam

7

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Augustine Rajakumar

8

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Ansgar Santel

9

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5 March 2020

Jan T Kielstein

10

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Asif Ahmed

11

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Maureen Chase

14

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William C Aird

16

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Sascha David

18

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Samir M Parikh

19

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Hermann Haller

17

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5 March 2020

language of work or name

English

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publication date

1 July 2015

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5 March 2020

published in

Critical Care Medicine

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5 March 2020

volume

43

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issue

7

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5 March 2020

page(s)

e230-40

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Simvastatin in the acute respiratory distress syndrome

5 March 2020

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12 July 2018

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Angiopoietin-1 requires IQ domain GTPase-activating protein 1 to activate Rac1 and promote endothelial barrier defense

12 July 2018

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Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium

12 July 2018

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Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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Simvastatin prevents vascular hyporeactivity during inflammation

26 September 2018

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HMG-CoA reductase inhibitor simvastatin profoundly improves survival in a murine model of sepsis

26 September 2018

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The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies

26 September 2018

1 reference

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Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues

26 September 2018

1 reference

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Cerivastatin improves survival of mice with lipopolysaccharide-induced sepsis

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25855898

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Continuation of Statin Therapy in Patients with Presumed Infection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25855898

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1097/CCM.0000000000000993

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25855898%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25855898%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

25855898

1 reference