Benzo-fused lactams from a diversity-oriented synthesis (DOS) library as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake (Q35611085)

9 August 2017

title

Benzo-fused lactams from a diversity-oriented synthesis (DOS) library as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake (English)

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9 August 2017

13

Stuart L Schreiber

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9 August 2017

Chris Dockendorff

1

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9 August 2017

Patrick W Faloon

2

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9 August 2017

Jun Pu

3

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9 August 2017

Miao Yu

4

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9 August 2017

Stephen Johnston

5

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9 August 2017

Melissa Bennion

6

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9 August 2017

Marsha Penman

7

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9 August 2017

Thomas J F Nieland

8

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9 August 2017

Sivaraman Dandapani

9

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9 August 2017

José R Perez

10

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9 August 2017

Benito Munoz

11

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9 August 2017

Michelle A Palmer

12

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9 August 2017

Monty Krieger

14

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9 August 2017

language of work or name

English

0 references

publication date

1 April 2015

1 reference

Bioorganic & Medicinal Chemistry Letters

9 August 2017

number of pages

6

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based on heuristic

inferred from page(s)

published in

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9 August 2017

volume

25

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9 August 2017

issue

10

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9 August 2017

page(s)

2100-2105

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Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport

9 August 2017

cites work

1 reference

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Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake

12 July 2018

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Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36

12 July 2018

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Safety and antiviral activity of the HCV entry inhibitor ITX5061 in treatment-naive HCV-infected adults: a randomized, double-blind, phase 1b study

12 July 2018

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Discovery of ITX 4520: a highly potent orally bioavailable hepatitis C virus entry inhibitor

12 July 2018

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Evaluation of ITX 5061, a scavenger receptor B1 antagonist: resistance selection and activity in combination with other hepatitis C virus antivirals

12 July 2018

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12 July 2018

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Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity

12 July 2018

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Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport

12 July 2018

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Glycine dimerization motif in the N-terminal transmembrane domain of the high density lipoprotein receptor SR-BI required for normal receptor oligomerization and lipid transport

12 July 2018

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Scavenger receptor class B, type I: a promising immunotherapy target.

12 July 2018

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An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors

12 July 2018

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Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors

12 July 2018

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Role of Scavenger Receptor Class B Type I in Hepatitis C Virus Entry: Kinetics and Molecular Determinants

12 July 2018

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Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor.

12 July 2018

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Mechanism and regulatory function of CpG signaling via scavenger receptor B1 in primary B cells

12 July 2018

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Scavenger Receptor BI Protects against Septic Death through Its Role in Modulating Inflammatory Response

12 July 2018

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Scavenger receptor BI boosts hepatocyte permissiveness to Plasmodium infection

12 July 2018

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Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection

12 July 2018

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High-Avidity Monoclonal Antibodies against the Human Scavenger Class B Type I Receptor Efficiently Block Hepatitis C Virus Infection in the Presence of High-Density Lipoprotein

12 July 2018

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Blockade of scavenger receptor class B type I raises high density lipoprotein cholesterol levels but exacerbates atherosclerotic lesion formation in apolipoprotein E deficient mice

12 July 2018

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High density lipoproteins facilitate hepatitis C virus entry through the scavenger receptor class B type I.

12 July 2018

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The role of the high-density lipoprotein receptor SR-BI in the lipid metabolism of endocrine and other tissues

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469080

Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469080

Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology

12 July 2018

1 reference

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Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

12 July 2018

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Escape from flatland: increasing saturation as an approach to improving clinical success.

12 July 2018

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Large scale preparation of silicon-functionalized SynPhase Polystyrene lanterns for solid-phase synthesis

25 September 2018

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Ring-opening and ring-closing reactions of a shikimic acid-derived substrate leading to diverse small molecules

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25900219

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2015.03.073

1 reference

9 August 2017

1 reference

9 August 2017

1 reference