A personalized medicine approach for Asian Americans with the aldehyde dehydrogenase 2*2 variant (Q35619842)

9 August 2017

1 reference

title

A personalized medicine approach for Asian Americans with the aldehyde dehydrogenase 2*2 variant (English)

1 reference

9 August 2017

main subject

personalized medicine

1 reference

6

Daria Mochly-Rosen

1 reference

9 August 2017

Eric R Gross

1

1 reference

9 August 2017

Vanessa O Zambelli

2

1 reference

9 August 2017

Bryce A Small

3

1 reference

9 August 2017

Julio C B Ferreira

4

1 reference

9 August 2017

Che-Hong Chen

5

1 reference

9 August 2017

publication date

29 September 2014

1 reference

Annual Review of Pharmacology and Toxicology

9 August 2017

published in

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9 August 2017

volume

55

1 reference

9 August 2017

page(s)

107-127

1 reference

Aldehyde dehydrogenase variation enhances effect of pesticides associated with Parkinson disease

9 August 2017

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12 July 2018

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12 July 2018

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Heavy binge drinking may increase risk of stroke in nonalcoholic hypertensives carrying variant ALDH2*2 gene allele

12 July 2018

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ALDH2 mediates 5-nitrofuran activity in multiple species

12 July 2018

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Mitigation of radiation-induced dermatitis by activation of aldehyde dehydrogenase 2 using topical alda-1 in mice

12 July 2018

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Screening for colorectal cancer: a guidance statement from the American College of Physicians

12 July 2018

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Neurodegeneration and motor dysfunction in mice lacking cytosolic and mitochondrial aldehyde dehydrogenases: implications for Parkinson's disease

12 July 2018

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Differences in susceptibility to inactivation of human aldehyde dehydrogenases by lipid peroxidation byproducts

12 July 2018

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ALDH2 activator inhibits increased myocardial infarction injury by nitroglycerin tolerance

12 July 2018

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Nitroglycerin use in myocardial infarction patients

12 July 2018

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Genome-wide association study of coronary artery disease in the Japanese

12 July 2018

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Role of aldehyde dehydrogenase 2 Glu504lys polymorphism in acute coronary syndrome

12 July 2018

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Gender differences in the effects of ADH1B and ALDH2 polymorphisms on alcoholism

12 July 2018

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice

12 July 2018

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SIRT3-dependent deacetylation exacerbates acetaminophen hepatotoxicity

12 July 2018

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Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

12 July 2018

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Alcohol drinking and esophageal cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population

12 July 2018

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Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotypes, alcohol drinking and the risk for stomach cancer in Chinese males.

12 July 2018

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12 July 2018

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12 July 2018

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Comparisons of catastrophizing, pain attitudes, and cold-pressor pain experience between Chinese and European Canadian young adults

12 July 2018

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Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variant

12 July 2018

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Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart

12 July 2018

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The enigma of nitroglycerin bioactivation and nitrate tolerance: news, views and troubles

12 July 2018

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Occupation and male infertility: glycol ethers and other exposures

12 July 2018

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Transient receptor potential A1 mediates acetaldehyde-evoked pain sensation

12 July 2018

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Quantity of ethanol absorption after excessive hand disinfection using three commercially available hand rubs is minimal and below toxic levels for humans

12 July 2018

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4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

12 July 2018

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Structural and Functional Consequences of Coenzyme Binding to the Inactive Asian Variant of Mitochondrial Aldehyde Dehydrogenase: ROLES OF RESIDUES 475 AND 487

12 July 2018

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Toxic side effects of drugs used to treat Chagas' disease (American trypanosomiasis)

12 July 2018

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Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin.

12 July 2018

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Aldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human health

12 July 2018

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Explaining the phenomenon of nitrate tolerance

12 July 2018

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An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation

12 July 2018

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Comparison between exhaled and sputum oxidative stress biomarkers in chronic airway inflammation

12 July 2018

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Correlation between alcohol-induced asthma and acetaldehyde dehydrogenase-2 genotype

12 July 2018

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Mechanism for benomyl action as a mitochondrial aldehyde dehydrogenase inhibitor in mice

12 July 2018

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Esophageal cancer and aldehyde dehydrogenase-2 genotypes in Japanese males.

12 July 2018

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Disposition of intravenous radioactive acyclovir

12 July 2018

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Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals

12 July 2018

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Pharmacokinetics of acyclovir after intravenous and oral administration.

12 July 2018

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Aldehyde dehydrogenase polymorphism and alcohol metabolism in alcoholics

12 July 2018

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Aldehyde dehydrogenase polymorphism in North American, South American, and Mexican Indian populations

12 July 2018

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Acetaldehyde syndrome after celiac plexus alcohol block

12 July 2018

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Evidence for a signal peptide at the amino-terminal end of human mitochondrial aldehyde dehydrogenase

12 July 2018

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Distribution of ADH2 and ALDH2 genotypes in different populations.

12 July 2018

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Role of cytosolic rat liver aldehyde dehydrogenase in the oxidation of acetaldehyde during ethanol metabolism in vivo

12 July 2018

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Assessment of the reproductive toxicity of inhalation exposure to ethyl tertiary butyl ether in male mice with normal, low active and inactive ALDH2.

12 July 2018

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Analysis of breath volatile organic compounds as a noninvasive tool to diagnose nonalcoholic fatty liver disease in children.

25 September 2018

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Inhibition of human alcohol and aldehyde dehydrogenases by acetaminophen: Assessment of the effects on first-pass metabolism of ethanol.

25 September 2018

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Alda-1 reduces cerebral ischemia/reperfusion injury in rat through clearance of reactive aldehydes

25 September 2018

1 reference

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Polymorphisms in alcohol-metabolizing enzymes and esophageal carcinoma susceptibility: a Dutch Caucasian case-control study

25 September 2018

1 reference

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Role of DRD2 and ALDH2 genes in bipolar II disorder with and without comorbid anxiety disorder.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

ALDH2 rs671 Polymorphism and coronary heart disease risk among Asian populations: a meta-analysis and meta-regression

25 September 2018

1 reference

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Interaction between novelty seeking and the aldehyde dehydrogenase 2 gene in heroin-dependent patients

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Common variants at 12q24 are associated with drinking behavior in Han Chinese

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Rapid simultaneous genotyping of polymorphisms in ADH1B and ALDH2 using high resolution melting assay.

25 September 2018

1 reference

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Genetic risk of hepatocellular carcinoma in patients with hepatitis C virus: a case control study

25 September 2018

1 reference

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Expression pattern, ethanol-metabolizing activities, and cellular localization of alcohol and aldehyde dehydrogenases in human large bowel: association of the functional polymorphisms of ADH and ALDH genes with hemorrhoids and colorectal cancer.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

The aldehyde dehydrogenase 2 gene is associated with heroin dependence.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Association of aldehyde dehydrogenase 2 gene polymorphism with pancreatic cancer but not colon cancer

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Impact of smoking on lung cancer risk is stronger in those with the homozygous aldehyde dehydrogenase 2 null allele in a Japanese population

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

A review of human carcinogens--Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

ALDH2 genetic polymorphism and the risk of type II diabetes mellitus in CAD patients

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Origin and dispersal of atypical aldehyde dehydrogenase ALDH2487Lys.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Association between personality traits and ALDH2 polymorphism in Japanese male alcoholics

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Impact of alcohol consumption with polymorphisms in alcohol-metabolizing enzymes on pancreatic cancer risk in Japanese

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Influence of ALDH2 genetic polymorphisms on aciclovir pharmacokinetics following oral administration of valaciclovir in Japanese end-stage renal disease patients.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Age-dependent neurodegeneration accompanying memory loss in transgenic mice defective in mitochondrial aldehyde dehydrogenase 2 activity.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

The association of mitochondrial aldehyde dehydrogenase gene (ALDH2) polymorphism with susceptibility to late-onset Alzheimer's disease in Chinese

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

A Glu487Lys polymorphism in the gene for mitochondrial aldehyde dehydrogenase 2 is associated with myocardial infarction in elderly Korean men.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

A polymorphism of the aldehyde dehydrogenase 2 gene is a risk factor for multiple lacunar infarcts in Japanese men: the Takahata Study.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

ALDH2 polymorphisms and bone mineral density in an elderly Japanese population

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Ethnic differences in thermal pain responses: a comparison of South Asian and White British healthy males

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Aldehyde dehydrogenase 2 plays a role in the bioactivation of nitroglycerin in humans

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Inactive aldehyde dehydrogenase-2 increased the risk of pancreatic cancer among smokers in a Japanese male population

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Assessment of association between mitochondrial aldehyde dehydrogenase polymorphism and Alzheimer's disease in an older Korean population

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Alcohol flushing, alcohol and aldehyde dehydrogenase genotypes, and risk for esophageal squamous cell carcinoma in Japanese men.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Aldehyde dehydrogenase 2 gene is a risk factor for myocardial infarction in Japanese men.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Removal of acetaldehyde from saliva by a slow-release buccal tablet of L-cysteine

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Screening for acetaldehyde dehydrogenase 2 genotype in alcohol-induced asthma by using the ethanol patch test

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Subunit communication in tetrameric class 2 human liver aldehyde dehydrogenase as the basis for half-of-the-site reactivity and the dominance of the oriental subunit in a heterotetramer

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Reliability of a flushing questionnaire and the ethanol patch test in screening for inactive aldehyde dehydrogenase-2 and alcohol-related cancer risk.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Deficiency in Mitochondrial Aldehyde Dehydrogenase Increases the Risk for Late-Onset Alzheimer's Disease in the Japanese Population

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

The aldehyde dehydrogenase 2 (ALDH2) Glu504Lys polymorphism interacts with alcohol drinking in the risk of stomach cancer

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Care and Outcomes of Asian-American Acute Myocardial Infarction Patients: Findings From the American Heart Association Get With The Guidelines-Coronary Artery Disease Program

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Effects of Variation at the ALDH2 Locus on Alcohol Metabolism, Sensitivity, Consumption, and Dependence in Europeans

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435945

Confirmation of ALDH2 as a Major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in a Japanese population

15 November 2018

1 reference

12 December 2020

Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease

1 reference

12 December 2020

Inactive aldehyde dehydrogenase 2 worsens glycemic control in patients with type 2 diabetes mellitus who drink low to moderate amounts of alcohol

1 reference

12 December 2020

Alcohol urticaria syndrome

1 reference

12 December 2020

Pain Tolerance: Differences According to Age, Sex and Race

1 reference

12 December 2020

Accumulation of hemoglobin-associated acetaldehyde with habitual alcohol drinking in the atypical ALDH2 genotype

1 reference

12 December 2020

A phase 1 study of nifurtimox in patients with relapsed/refractory neuroblastoma

1 reference

12 December 2020

Common single nucleotide polymorphisms in Japanese patients with essential hypertension: aldehyde dehydrogenase 2 gene as a risk factor independent of alcohol consumption

1 reference

12 December 2020

Functional compartmentation of acetaldehyde oxidation in rat liver

1 reference

12 December 2020

Ethnic contact urticaria to alcohol

1 reference

12 December 2020

Hangover and the risk of stroke in middle-aged men

1 reference

12 December 2020

Apparent monomorphism of ALDH2 in seven American Indian populations

1 reference

12 December 2020

Reproductive toxicity of ethylene glycol monoethyl ether in Aldh2 knockout mice

1 reference

12 December 2020

Identification of a 54-kDa mitochondrial acetaminophen-binding protein as aldehyde dehydrogenase

1 reference

12 December 2020

10.1146/ANNUREV-PHARMTOX-010814-124915

Identifiers

DOI

1 reference

9 August 2017

1 reference

9 August 2017

1 reference