4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1 (Q35941218)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684094%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684094%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

main subject

neuropathic pain

0 references

neurogenic inflammation

1 reference

8

1 reference

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3 January 2020

14

David Julius

1 reference

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3 January 2020

12

Allan I Basbaum

1 reference

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3 January 2020

4

Diana M Bautista

1 reference

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3 January 2020

7

Noritaka Imamachi

1 reference

3 January 2020

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Marcello Trevisani

1

1 reference

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3 January 2020

Jan Siemens

2

1 reference

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3 January 2020

Serena Materazzi

3

1 reference

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3 January 2020

Romina Nassini

5

1 reference

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3 January 2020

Barbara Campi

6

1 reference

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3 January 2020

Riccardo Patacchini

9

1 reference

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3 January 2020

Graeme S Cottrell

10

1 reference

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3 January 2020

Raffaele Gatti

11

1 reference

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3 January 2020

Nigel W Bunnett

13

1 reference

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3 January 2020

Pierangelo Geppetti

15

1 reference

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3 January 2020

language of work or name

English

0 references

publication date

7 August 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684094%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

3 January 2020

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

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3 January 2020

volume

104

1 reference

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3 January 2020

issue

33

1 reference

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3 January 2020

page(s)

13519-13524

1 reference

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Post-endocytic sorting of calcitonin receptor-like receptor and receptor activity-modifying protein 1

3 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Direct activation of the ion channel TRPA1 by Ca2+.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

TRP channel activation by reversible covalent modification

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Spider toxins activate the capsaicin receptor to produce inflammatory pain.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Protein carbonylation, cellular dysfunction, and disease progression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

An introduction to TRP channels

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Pungent products from garlic activate the sensory ion channel TRPA1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Molecular mechanisms of nociception

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Protein carbonyl groups' content as a useful clinical marker of antioxidant barrier impairment in plasma of children with juvenile chronic arthritis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Impaired nociception and pain sensation in mice lacking the capsaicin receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

The cloned capsaicin receptor integrates multiple pain-producing stimuli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Quantitative assessment of tactile allodynia in the rat paw

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Transient receptor potential channel A1 is directly gated by calcium ions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Selective blockade of the capsaicin receptor TRPV1 attenuates bone cancer pain.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Elevated protein carbonyls as plasma markers of oxidative stress in acute pancreatitis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948902

4-Hydroxynonenal formation during ischemia and reperfusion of rat small intestine

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17684094

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17684094

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0705923104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684094%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

0 references

1 reference

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3 January 2020

1 reference