Control of autoimmunity by naturally arising regulatory CD4+ T cells (Q35623006)

9 August 2017

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title

Control of autoimmunity by naturally arising regulatory CD4+ T cells (English)

1 reference

9 August 2017

3

Shimon Sakaguchi

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9 August 2017

Shohei Hori

1

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9 August 2017

Takeshi Takahashi

series ordinal

2

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9 August 2017

publication date

1 January 2003

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9 August 2017

published in

Advances in Immunology

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9 August 2017

volume

81

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9 August 2017

page(s)

331-371

1 reference

Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers

9 August 2017

cites work

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7 January 2021

Projection of an immunological self shadow within the thymus by the aire protein

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7 January 2021

Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment

1 reference

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7 January 2021

CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10

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7 January 2021

Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes

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7 January 2021

Origin of regulatory T cells with known specificity for antigen

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7 January 2021

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

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7 January 2021

The early IL-4 response to Leishmania major and the resulting Th2 cell maturation steering progressive disease in BALB/c mice are subject to the control of regulatory CD4+CD25+ T cells.

1 reference

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7 January 2021

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

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7 January 2021

CD4+CD25high regulatory cells in human peripheral blood

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7 January 2021

Modulation of Fas-dependent apoptosis: a dynamic process controlling both the persistence and death of CD4 regulatory T cells and effector T cells

1 reference

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7 January 2021

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Organ-specific autoimmunity induced by adult thymectomy and cyclophosphamide-induced lymphopenia

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7 January 2021

Requirement for diverse, low-abundance peptides in positive selection of T cells

1 reference

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7 January 2021

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomena

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https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

In thymic selection, peptide diversity gives and takes away

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice

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https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Tumor antigens recognized by T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

T-cell tolerance by clonal anergy in transgenic mice with nonlymphoid expression of MHC class II I–E

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

B cells and professional APCs recruit regulatory T cells via CCL4

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Anergic T cells act as suppressor cells in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4+CD25+ T cells as immunoregulatory T cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Infectious tolerance.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Regulatory T cells: the physiology of autoreactivity in dominant tolerance and "quality control" of immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Hyper immunoglobulin E response in mice with monoclonal populations of B and T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected].

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4(+)CD25(+) T cells facilitate the induction of T cell anergy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Interleukin 2 signaling is required for CD4(+) regulatory T cell function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Regulatory T cells in spontaneous autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Quantitative analysis of the T cell repertoire selected by a single peptide-major histocompatibility complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Organ-specific autoimmunity induced by lymphopenia.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Selecting and maintaining a diverse T-cell repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Identification of regulatory T cells in tolerated allografts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Depletion of RT6.1+ T lymphocytes induces diabetes in resistant biobreeding/Worcester (BB/W) rats

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Probing degeneracy in T-cell recognition using peptide combinatorial libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Peripheral expansion of thymus-derived regulatory cells in anti-myelin basic protein T cell receptor transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Control of regulatory T cell development by the transcription factor Foxp3

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Peripheral clonal elimination of functional T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

T cell tolerance by clonal elimination in the thymus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Genetic susceptibility to post-thymectomy autoimmune diseases in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Interleukin-10-deficient mice develop chronic enterocolitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: a role of CD40 in regulatory T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

1 reference

7 January 2021

Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Anergic T cells as suppressor cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

A very high level of crossreactivity is an essential feature of the T-cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Some quantitative aspects of T-cell repertoire selection: the requirement for regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Control of immune pathology by regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

The danger model: a renewed sense of self

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Interception of the development of self tolerance in fetal lambs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Decoding the patterns of self and nonself by the innate immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Self-ignorance in the peripheral T-cell pool

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

A model for developmentally acquired thymus-dependent tolerance to central and peripheral antigens

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Regulatory T cells in thymic epithelium-induced tolerance. I. Suppression of mature peripheral non-tolerant T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Lymphocytes selected in allogeneic thymic epithelium mediate dominant tolerance toward tissue grafts of the thymic epithelium haplotype

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

B7/CD28-Dependent CD4+CD25+ Regulatory T Cells Are Essential Components of the Memory-Protective Immunity to Candida albicans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Transfusions enriched for W3/25+ helper/inducer T lymphocytes prevent spontaneous diabetes in the BB/W rat

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Germ-free condition and the susceptibility of BALB/c mice to post-thymectomy autoimmune gastritis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD25+CD4+ T cells contribute to the control of memory CD8+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Positional cloning of the APECED gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Negative selection of lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Tolerance induced by thymic epithelial grafts in birds

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Repertoire requirements of CD4+ T cells that prevent spontaneous autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Peptide specificity of thymic selection of CD4+CD25+ T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

"Infectious" transplantation tolerance.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Clonal anergy induced in mature V beta 6+ T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

A nondeletional mechanism of thymic self tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Peripheral selection of the T cell repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Preferential recognition of self antigens despite normal thymic deletion of CD4(+)CD25(+) regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Type 1 T regulatory cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Regulatory T cells: key controllers of immunologic self-tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Animal models of autoimmunity and their relevance to human diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Policing the regulators

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Thymus and autoimmunity: capacity of the normal thymus to produce pathogenic self-reactive T cells and conditions required for their induction of autoimmune disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

T cell-mediated maintenance of natural self-tolerance: its breakdown as a possible cause of various autoimmune diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Thymic epithelium tolerizes for histocompatibility antigens

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

The thymus contains a high frequency of cells that prevent autoimmune diabetes on transfer into prediabetic recipients

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Peripheral autoantigen induces regulatory T cells that prevent autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Regulatory T cells in the control of autoimmunity: the essential role of transforming growth factor beta and interleukin 4 in the prevention of autoimmune thyroiditis in rats by peripheral CD4(+)CD45RC- cells and CD4(+)CD8(-) thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

The third function of the thymus.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4+ CD25+ suppressor T cells: more questions than answers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Control of intestinal inflammation by regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25+ and CD25- subpopulations.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. III. Analysis of regulatory cells suppressing the induction of thyroiditis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4+CD25+ T-cell development is regulated by at least 2 distinct mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

The subpopulation of CD4+CD25+ splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Anergic T cells actively suppress T cell responses via the antigen-presenting cell

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Self tolerance and localized autoimmunity. Mouse models of autoimmune disease that suggest tissue-specific suppressor T cells are involved in self tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

The emerging role of CTLA-4 as an immune attenuator

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

CD4(+) T cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Cutting edge: CD4+CD25+ alloantigen-specific immunoregulatory cells that can prevent CD8+ T cell-mediated graft rejection: implications for anti-CD154 immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Anergic T cells inhibit the antigen-presenting function of dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

How do monoclonal antibodies induce tolerance? A role for infectious tolerance?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

The shaping of the brain-specific T lymphocyte repertoire in the thymus.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: evidence for two distinct regulatory mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Regulatory T cells overexpress a subset of Th2 gene transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

Analysis of Autoimmunity through Experimental Models of Thyroiditis and Allergic Encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2803%2981008-8

7 January 2021

10.1016/S0065-2776(03)81008-8

Identifiers

DOI

1 reference

9 August 2017

1 reference