Identification of a novel potent, selective and cell permeable inhibitor of protein kinase CK2 from the NIH/NCI Diversity Set Library (Q35627487)

9 August 2017

title

Identification of a novel potent, selective and cell permeable inhibitor of protein kinase CK2 from the NIH/NCI Diversity Set Library (English)

1 reference

9 August 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25963666%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jennifer Hochscherf

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25963666%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Nina Bjelkerup Jensen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25963666%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Olaf-Georg Issinger

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25963666%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

publication date

12 May 2015

1 reference

Molecular and Cellular Biochemistry

9 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25963666%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

406

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25963666%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

1-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25963666%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

151-161

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25963666%20AND%20SRC:MED&resulttype=core&format=json

Casein kinases: pleiotropic mediators of cellular regulation

11 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Protein kinase CK2 and its role in cellular proliferation, development and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Protein kinase CK2 in human diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Protein kinase CK2 in health and disease: CK2: a key player in cancer biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Protein kinase CK2 in health and disease: Cellular functions of protein kinase CK2: a dynamic affair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Enzymatic activity with an incomplete catalytic spine: insights from a comparative structural analysis of human CK2α and its paralogous isoform CK2α'

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Structure of the human protein kinase CK2 catalytic subunit CK2α' and interaction thermodynamics with the regulatory subunit CK2β

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Isolation and characterization of recombinant human casein kinase II subunits alpha and beta from bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Quaternary structure of casein kinase 2. Characterization of multiple oligomeric states and relation with its catalytic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

A global view of CK2 function and regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Primary and secondary interactions between CK2alpha and CK2beta lead to ring-like structures in the crystals of the CK2 holoenzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Biochemical characterization of CK2alpha and alpha' paralogues and their derived holoenzymes: evidence for the existence of a heterotrimeric CK2alpha'-holoenzyme forming trimeric complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Structural determinants of protein kinase CK2 regulation by autoinhibitory polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

The protein kinase CK2(Andante) holoenzyme structure supports proposed models of autoregulation and trans-autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Evidence for aggregation of protein kinase CK2 in the cell: a novel strategy for studying CK2 holoenzyme interaction by BRET(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Subcellular localization of protein kinase CK2. A key to its function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Biochemical characterization of the recombinant human Drosophila homologues Timekeeper and Andante involved in the Drosophila circadian oscillator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Protein kinase CK2 as a druggable target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Evolved to be active: sulfate ions define substrate recognition sites of CK2alpha and emphasise its exceptional role within the CMGC family of eukaryotic protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Expression and purification of PI3 kinase alpha and development of an ATP depletion and an alphascreen PI3 kinase activity assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Evaluating CK2 activity with the antibody specific for the CK2-phosphorylated form of a kinase-targeting cochaperone Cdc37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

The protein kinase complement of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

The selectivity of inhibitors of protein kinase CK2: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

TF--a novel cell-permeable and selective inhibitor of human protein kinase CK2 induces apoptosis in the prostate cancer cell line LNCaP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Protein kinase CK2 inhibition is associated with the destabilization of HIF-1α in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Resorufin: a lead for a new protein kinase CK2 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Structure-based discovery of novel flavonol inhibitors of human protein kinase CK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

A subnanomolar fluorescent probe for protein kinase CK2 interaction studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Discovery and characterization of synthetic 4'-hydroxyflavones-New CK2 inhibitors from flavone family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Characterization of CK2 holoenzyme variants with regard to crystallization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

IRAK1: oncotarget in MDS and AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

PIM kinase (and Akt) biology and signaling in tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Targeting Pim kinases for cancer treatment: opportunities and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-015-2433-Z

Characterization of casein kinase II in human colonic carcinomas after heterotransplantation into nude mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25963666

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Casein kinase II is elevated in solid human tumours and rapidly proliferating non-neoplastic tissue

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25963666

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence for the induction of casein kinase II in bovine lymphocytes transformed by the intracellular protozoan parasite Theileria parva

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25963666

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11010-015-2433-Z

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25963666%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference