Biochemical characterization of CK2alpha and alpha' paralogues and their derived holoenzymes: evidence for the existence of a heterotrimeric CK2alpha'-holoenzyme forming trimeric complexes. (Q39968855)

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English	Biochemical characterization of CK2alpha and alpha' paralogues and their derived holoenzymes: evidence for the existence of a heterotrimeric CK2alpha'-holoenzyme forming trimeric complexes.	scientific article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18574672%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Biochemical characterization of CK2alpha and alpha' paralogues and their derived holoenzymes: evidence for the existence of a heterotrimeric CK2alpha'-holoenzyme forming trimeric complexes (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18574672%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Birgitte B Olsen

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18574672%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Karsten Niefind

3

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9 January 2020

author name string

Tine Rasmussen

2

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9 January 2020

Olaf-Georg Issinger

4

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Europe PubMed Central

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9 January 2020

publication date

24 June 2008

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9 January 2020

Molecular and Cellular Biochemistry

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Europe PubMed Central

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9 January 2020

316

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9 January 2020

1-2

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Europe PubMed Central

PubMed publication ID

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9 January 2020

37-47

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18574672%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Tetrabromobenzotriazole (TBBt) and tetrabromobenzimidazole (TBBz) as selective inhibitors of protein kinase CK2: evaluation of their effects on cells and different molecular forms of human CK2.

1 reference

https://api.crossref.org/works/10.1007%2FS11010-008-9824-3

21 January 2018

Features and potentials of ATP-site directed CK2 inhibitors

1 reference

https://api.crossref.org/works/10.1007%2FS11010-008-9824-3

21 January 2018

Evaluation of 4,5,6,7-tetrahalogeno-1H-isoindole-1,3(2H)-diones as inhibitors of human protein kinase CK2.

1 reference

https://api.crossref.org/works/10.1007%2FS11010-008-9824-3

21 January 2018

Reconstitution of normal and hyperactivated forms of casein kinase-2 by variably mutated beta-subunits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the .alpha. and .beta. subunits of casein kinase 2 by far-UV CD spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyrazole carboxamides and carboxylic acids as protein kinase inhibitors in aberrant eukaryotic signal transduction: induction of growth arrest in MCF-7 cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase CK2 and its role in cellular proliferation, development and pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GTP plus water mimic ATP in the active site of protein kinase CK2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of the catalytic subunit of protein kinase CK2 from Zea mays at 2.1 A resolution.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Globozoospermia in mice lacking the casein kinase II alpha' catalytic subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase CK2: a challenge to canons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-based design and synthesis of novel macrocyclic pyrazolo[1,5-a] [1,3,5]triazine compounds as potent inhibitors of protein kinase CK2 and their anticancer activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ser2 is the autophosphorylation site in the beta subunit from bicistronically expressed human casein kinase-2 and from native rat liver casein kinase-2 beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of polylysine on casein-kinase-2 activity is influenced by both the structure of the protein/peptide substrates and the subunit composition of the enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of recombinant human casein kinase II subunits alpha and beta from bacteria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase CK2 signal in neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of human cDNA clones encoding the alpha and the alpha' subunits of casein kinase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and exploitation of CK2 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promiscuous subunit interactions: a possible mechanism for the regulation of protein kinase CK2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase CK2: evidence for a protein kinase CK2beta subunit fraction, devoid of the catalytic CK2alpha subunit, in mouse brain and testicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual effect of lysine‐rich polypeptides on the activity of protein kinase CK2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of protein kinase CK2 nuclear signaling in neoplasia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of the CK2alpha'-based holoenzyme, an isozyme of CK2alpha: a comparative analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CK2: a protein kinase in need of control.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CK2, a protein kinase of the next millennium

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary and secondary interactions between CK2alpha and CK2beta lead to ring-like structures in the crystals of the CK2 holoenzyme.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of calmodulin fragments by protein kinase CK2. Mechanistic aspects and structural consequences.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of CK2 holoenzyme variants with regard to crystallization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quaternary structure of casein kinase 2. Characterization of multiple oligomeric states and relation with its catalytic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The catalytic subunit of human protein kinase CK2 structurally deviates from its maize homologue in complex with the nucleotide competitive inhibitor emodin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Casein kinases: pleiotropic mediators of cellular regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophosphorylation at the regulatory beta subunit reflects the supramolecular organization of protein kinase CK2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A filamentous form of Drosophila casein kinase II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Casein kinase II is elevated in solid human tumours and rapidly proliferating non-neoplastic tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

One-thousand-and-one substrates of protein kinase CK2?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the beta subunit of casein kinase II in human A431 cells. Identification of the autophosphorylation site and a site phosphorylated by p34cdc2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Features of selective kinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A global view of CK2 function and regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase CK2: a newcomer in the 'druggable kinome'.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18574672

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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