Delivery systems for pulmonary gene therapy (Q35627914)

9 August 2017

1 reference

title

Delivery systems for pulmonary gene therapy (English)

1 reference

9 August 2017

0 references

Ajay Gautam

1

1 reference

PubMed ID

14720074

9 August 2017

Clifford J Waldrep

series ordinal

2

1 reference

PubMed ID

14720074

9 August 2017

Charles L Densmore

series ordinal

3

1 reference

9 August 2017

1 January 2002

1 reference

Treatments in Respiratory Medicine

9 August 2017

1 reference

9 August 2017

1

1 reference

9 August 2017

1

1 reference

9 August 2017

35-46

1 reference

https://scigraph.springernature.com/pub.10.1007/bf03257161

9 August 2017

0 references

cites work

Retroviruses as vectors

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Retroviral vectors efficiently transduce basal and secretory airway epithelial cells in vitro resulting in persistent gene expression in organotypic culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

HIV, but not murine leukemia virus, vectors mediate high efficiency gene transfer into freshly isolated G0/G1 human hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Construction of encapsidated (gutted) adenovirus minichromosomes and their application to rescue of photoreceptor degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Strategies to adapt adenoviral vectors for targeted delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Engineering viral vectors to subvert the airway defense response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

A system for the propagation of adenoviral vectors with genetically modified receptor specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

EGTA enhancement of adenovirus-mediated gene transfer to mouse tracheal epithelium in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Perfluorochemical liquid enhances adeno-associated virus-mediated transgene expression in lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Trans-splicing vectors expand the utility of adeno-associated virus for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Cationic liposome-mediated transfection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Long-term survival of immunocompetent rats with intraperitoneal colon carcinoma tumors using herpes simplex thymidine kinase/ganciclovir and IL-2 treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Cholesterol enhances cationic liposome-mediated DNA transfection of human respiratory epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Improved DNA: liposome complexes for increased systemic delivery and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Gene transfer by guanidinium-cholesterol cationic lipids into airway epithelial cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

In vivo gene delivery to the lung using polyethylenimine and fractured polyamidoamine dendrimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Deoxyribonucleic acid-polylysine complexes. Structure and nucleotide specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Examination of the biophysical interaction between plasmid DNA and the polycations, polylysine and polyornithine, as a basis for their differential gene transfection in-vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Polyethylenimine-based intravenous delivery of transgenes to mouse lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Aerosol delivery of robust polyethyleneimine-DNA complexes for gene therapy and genetic immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Inhibition of experimental lung metastasis by aerosol delivery of PEI-p53 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Growth suppression of established human osteosarcoma lung metastases in mice by aerosol gene therapy with PEI-p53 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Pulmonary cytokine responses associated with PEI-DNA aerosol gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Interaction of liposomal and polycationic transfection complexes with pulmonary surfactant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Mechanism of lipoplex gene delivery in mouse lung: binding and internalization of fluorescent lipid and DNA components

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

In vivo transfer and expression of the lacZ gene in the mouse lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Intratracheal administration of interleukin 12 plasmid-cationic lipid complexes inhibits murine lung metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Development of cationic liposome formulations for intratracheal gene therapy of early lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Comparison between intratracheal and intravenous administration of liposome-DNA complexes for cystic fibrosis lung gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Aerosol gene delivery in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Delivery of DNA-cationic liposome complexes by small-particle aerosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

A concentrated and stable aerosol formulation of cationic lipid:DNA complexes giving high-level gene expression in mouse lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Simulated lung transfection by nebulization of liposome cDNA complexes using a cascade impactor seeded with 2-CFSME0-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Aerosolization of cationic lipid:pDNA complexes--in vitro optimization of nebulizer parameters for human clinical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Aerosol delivery of lipid:DNA complexes to lungs of rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Aerosol-mediated delivery of recombinant adenovirus to the airways of nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Genetic immunization with lung-targeting macroaggregated polyethyleneimine-albumin conjugates elicits combined systemic and mucosal immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

CT-guided intratumoral gene therapy in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Adenoviral-mediated p53 gene transfer to non-small cell lung cancer through endobronchial injection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Functions of the cystic fibrosis transmembrane conductance regulator protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Restoration of cyclic adenosine monophosphate-stimulated chloride channel activity in human cystic fibrosis tracheobronchial submucosal gland cells by adenovirus-mediated and cationic lipid-mediated gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

CFTR gene transduction in neonatal rabbits using an adeno-associated virus (AAV) vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Cystic fibrosis sputum: a barrier to the transport of nanospheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Enhanced distribution of adenovirus-mediated gene transfer to lung parenchyma by perfluorochemical liquid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Increasing epithelial junction permeability enhances gene transfer to airway epithelia In vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Biodistribution and transgene expression with nonviral cationic vector/DNA complexes in the lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Effective treatment of early endobronchial cancer with regional administration of liposome-p53 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Successful treatment of primary and disseminated human lung cancers by systemic delivery of tumor suppressor genes using an improved liposome vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in Rb+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Intravenous cytokine gene delivery by lipid-DNA complexes controls the growth of established lung metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

A gene therapy for cancer using intramuscular injection of plasmid DNA encoding interferon alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Gene transfer of herpes simplex virus type I thymidine kinase gene as a drug sensitivity gene into human lung cancer cell lines using retroviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

A phase I study of adenovirus-mediated wild-type p53 gene transfer in patients with advanced non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Adenovirus-mediated wild-type p53 gene expression radiosensitizes non-small cell lung cancer cells but not normal lung fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Transfection of nasal mucosa with a normal alpha1-antitrypsin gene in alpha1-antitrypsin-deficient subjects: comparison with protein therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Aerosol and intravenous transfection of human alpha 1-antitrypsin gene to lungs of rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Transgene expression in mouse airway epithelium by aerosol gene therapy with PEI-DNA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

21 January 2018

The genetics of asthma

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

21 January 2018

Asthma and inflammation

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

The glucocorticoid receptor gene as a candidate for gene therapy in asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

DNA antisense therapy for asthma in an animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03257161

Intranasal therapy with an adenoviral vector containing the murine interleukin-12 gene eradicates osteosarcoma lung metastases

21 January 2018

1 reference

12 December 2020

Mucosal IL-12 gene delivery inhibits allergic airways disease and restores local antiviral immunity

1 reference

12 December 2020

Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection

1 reference

12 December 2020

Targeted gene delivery to pulmonary endothelium by anti-PECAM antibody

1 reference

12 December 2020

An improved system for packaging recombinant adeno-associated virus vectors capable of in vivo transduction.

1 reference

12 December 2020

In vitro and in vivo biology of recombinant adenovirus vectors with E1, E1/E2A, or E1/E4 deleted.

1 reference

12 December 2020

Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted

1 reference

12 December 2020

Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors

1 reference

12 December 2020

Enhanced gene expression in mouse lung after PEI-DNA aerosol delivery

1 reference

12 December 2020

Construction of adenovirus vectors through Cre-lox recombination

1 reference

12 December 2020

Cytokine and eosinophil responses in the lung, peripheral blood, and bone marrow compartments in a murine model of allergen-induced airways inflammation

1 reference

12 December 2020

P53 tumor suppressor gene therapy for cancer

1 reference

12 December 2020

Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations

1 reference

12 December 2020

CpG oligodeoxynucleotides can reverse Th2-associated allergic airway responses and alter the B7.1/B7.2 expression in a murine model of asthma

1 reference

12 December 2020

Gene transfer by guanidinium-cholesterol: dioleoylphosphatidyl-ethanolamine liposome-DNA complexes in aerosol

1 reference

12 December 2020

Ultrasonic nebulization of cationic lipid-based gene delivery systems for airway administration

1 reference

12 December 2020

Integrating adenovirus-adeno-associated virus hybrid vectors devoid of all viral genes.

1 reference

12 December 2020

Intratracheal gene delivery to the mouse airway: characterization of plasmid DNA expression and pharmacokinetics

1 reference

12 December 2020

Safety of single-dose administration of an adeno-associated virus (AAV)-CFTR vector in the primate lung.

1 reference

12 December 2020

Mucosal IFN-gamma gene transfer inhibits pulmonary allergic responses in mice

1 reference

12 December 2020

Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung

1 reference

12 December 2020

Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.

1 reference

12 December 2020

Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmid: cationic lipid complexes

1 reference

12 December 2020

A double-blind, placebo controlled, dose ranging study to evaluate the safety and biological efficacy of the lipid-DNA complex GR213487B in the nasal epithelium of adult patients with cystic fibrosis

1 reference

12 December 2020

A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis

1 reference

12 December 2020

Targeted vectors for gene therapy.

1 reference

12 December 2020

Inhibition of tumor growth correlates with the expression level of a human angiostatin transgene in transfected B16F10 melanoma cells.

1 reference

12 December 2020

The use of cationic liposomes DC-CHOL/DOPE and DDAB/DOPE for direct transfer of Escherichia coli cytosine deaminase gene into growing melanoma tumors.

1 reference

12 December 2020

A replication-incompetent adenovirus vector with the preterminal protein gene deleted efficiently transduces mouse ears

1 reference

12 December 2020

Recombinant adenovirus expressing wild-type p53 is antiangiogenic: a proposed mechanism for bystander effect

1 reference

12 December 2020

Pharmacokinetics and in vivo gene transfer of plasmid DNA complexed with mannosylated poly(L-lysine) in mice

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF03257161

1 reference

9 August 2017

0 references

1 reference

PubMed ID

14720074