Murine bilateral retinoblastoma exhibiting rapid-onset, metastatic progression and N-myc gene amplification (Q35629633)

9 August 2017

title

Murine bilateral retinoblastoma exhibiting rapid-onset, metastatic progression and N-myc gene amplification (English)

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9 August 2017

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bilateral retinoblastoma

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6

Tyler Jacks

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9 August 2017

David MacPherson

1

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9 August 2017

Karina Conkrite

2

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9 August 2017

Mandy Tam

3

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9 August 2017

Shizuo Mukai

4

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9 August 2017

David Mu

5

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9 August 2017

language of work or name

English

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publication date

18 January 2007

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9 August 2017

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9 August 2017

volume

26

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9 August 2017

issue

3

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9 August 2017

page(s)

784-794

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Inactivation of the p53 pathway in retinoblastoma.

9 August 2017

cites work

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Mouse genomic representational oligonucleotide microarray analysis: detection of copy number variations in normal and tumor specimens

27 July 2018

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Compensation by tumor suppressor genes during retinal development in mice and humans

27 July 2018

1 reference

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Use of preclinical models to improve treatment of retinoblastoma

27 July 2018

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27 July 2018

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KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers

27 July 2018

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Detection of chromosomal imbalances in retinoblastoma by matrix-based comparative genomic hybridization

27 July 2018

1 reference

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Representational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variation

27 July 2018

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Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

27 July 2018

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Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system

27 July 2018

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27 July 2018

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Pax6 is required for the multipotent state of retinal progenitor cells

27 July 2018

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Retinal stem cells in the adult mammalian eye

27 July 2018

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Developmental basis of retinal-specific induction of cancer by RB mutation.

27 July 2018

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p107 is a suppressor of retinoblastoma development in pRb-deficient mice

27 July 2018

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Subsets of retinal progenitors display temporally regulated and distinct biases in the fates of their progeny.

27 July 2018

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27 July 2018

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Shared role of the pRB-related p130 and p107 proteins in limb development

27 July 2018

1 reference

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Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice

27 July 2018

1 reference

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Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

Expression and amplification of the N-myc gene in primary retinoblastoma

27 July 2018

1 reference

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Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

27 July 2018

1 reference

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Mutation and cancer: statistical study of retinoblastoma

27 July 2018

1 reference

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Tumour induction by the retinoblastoma mutation is independent of N-myc expression.

27 July 2018

1 reference

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Requirement for a functional Rb-1 gene in murine development

27 July 2018

1 reference

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Effects of an Rb mutation in the mouse

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

27 July 2018

1 reference

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The Occurrence of New Retinoblastomas after Treatment

27 July 2018

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27 July 2018

1 reference

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Distinct patterns of expression of the RB gene family in mouse and human retina

25 September 2018

1 reference

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Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130

25 September 2018

1 reference

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Cell type-specific effects of Rb deletion in the murine retina.

25 September 2018

1 reference

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Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

The first knockout mouse model of retinoblastoma

25 September 2018

1 reference

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Rb regulates proliferation and rod photoreceptor development in the mouse retina

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

Approaches to treatment for extraocular retinoblastoma: Children's Hospital Los Angeles experience

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

Development of New Retinoblastomas After 6 Cycles of Chemoreduction for Retinoblastoma in 162 Eyes of 106 Consecutive Patients

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

Extra-embryonic function of Rb is essential for embryonic development and viability

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

Comparative genomic hybridization of 49 primary retinoblastoma tumors identifies chromosomal regions associated with histopathology, progression, and patient outcome.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

High level amplification of N-MYC is not associated with adverse histology or outcome in primary retinoblastoma tumours

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

Stem cells in the vertebrate retina

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

p107 and p130: versatile proteins with interesting pockets

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

Retinoblastoma in transgenic mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794380

Minimal regions of chromosomal imbalance in retinoblastoma detected by comparative genomic hybridization

25 September 2018

1 reference

12 December 2020

Optic nerve invasion of retinoblastoma. Metastatic potential and clinical risk factors

1 reference

12 December 2020

Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53

1 reference

12 December 2020

Immunohistochemical features of the human retina and retinoblastoma

1 reference

12 December 2020

Targeted disruption of p107: functional overlap between p107 and Rb

1 reference

12 December 2020

The topography of bilateral retinoblastoma lesions

1 reference

12 December 2020

Detection of chromosome imbalances in retinoblastoma by parallel karyotype and CGH analyses

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7601515

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9 August 2017

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9 August 2017

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