Chemical activation of the mechanotransduction channel Piezo1 (Q35639553)

9 August 2017

title

Chemical activation of the mechanotransduction channel Piezo1 (English)

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9 August 2017

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General Immunology and Microbiology

determination method or standard

4 February 2022

domain-ontology-based fuzzy-powered named-entity recognition matcher

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Molecular Biology

4 February 2022

determination method or standard

domain-ontology-based fuzzy-powered named-entity recognition matcher

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General Medicine

4 February 2022

determination method or standard

domain-ontology-based fuzzy-powered named-entity recognition matcher

15

Ardem Patapoutian

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9 August 2017

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Michael Bandell

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9 August 2017

3

Adrienne E Dubin

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9 August 2017

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Jayanti Mathur

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9 August 2017

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Bertrand Coste

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9 August 2017

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Ruhma Syeda

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9 August 2017

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Mauricio Montal

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9 August 2017

Jie Xu

2

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9 August 2017

Truc Huynh

6

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9 August 2017

Jason Matzen

7

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9 August 2017

Jianmin Lao

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9 August 2017

David C Tully

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9 August 2017

Ingo H Engels

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9 August 2017

H Michael Petrassi

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9 August 2017

Andrew M Schumacher

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9 August 2017

language of work or name

English

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publication date

22 May 2015

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9 August 2017

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9 August 2017

volume

4

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Piezo2 is the major transducer of mechanical forces for touch sensation in mice

9 August 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Piezo1 integration of vascular architecture with physiological force.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Piezo1, a mechanically activated ion channel, is required for vascular development in mice.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Mutations in PIEZO2 cause Gordon syndrome, Marden-Walker syndrome, and distal arthrogryposis type 5.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Piezo2 is required for Merkel-cell mechanotransduction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

TRPV1 structures in distinct conformations reveal activation mechanisms

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Inflammatory signals enhance piezo2-mediated mechanosensitive currents

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Sensing pressure with ion channels

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Piezo proteins are pore-forming subunits of mechanically activated channels

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

The role of Drosophila Piezo in mechanical nociception

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

The mechanosensitive ion channel Piezo1 is inhibited by the peptide GsMTx4

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Molecular mechanisms of mechanotransduction in mammalian sensory neurons

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Droplet interface bilayers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Screening blockers against a potassium channel with a droplet interface bilayer array

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Lysophosphatidic acid stimulates neurotransmitter-like conductance changes that precede GABA and L-glutamate in early, presumptive cortical neuroblasts.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

A mammalian two pore domain mechano-gated S-like K+ channel

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interactions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

12 July 2018

TRP channels and pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

Molecular basis for species-specific sensitivity to "hot" chili peppers

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456433

25 September 2018

Identifiers

DOI

10.7554/ELIFE.07369

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9 August 2017

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9 August 2017

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