Alternative mRNA splicing of corepressors generates variants that play opposing roles in adipocyte differentiation. (Q35639785)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065574%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Alternative mRNA splicing of corepressors generates variants that play opposing roles in adipocyte differentiation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065574%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065574%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Brian A Jonas

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065574%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Brenda J Mengeling

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065574%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Martin L Privalsky

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065574%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

0 references

publication date

7 November 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065574%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

16 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065574%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

286

1 reference

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16 January 2020

page(s)

44988-44999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065574%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

52

1 reference

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describes a project that uses

16 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3247966/fullTextXML

inferred from PubMed Central ID database lookup

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Estrogen receptors recruit SMRT and N-CoR corepressors through newly recognized contacts between the corepressor N terminus and the receptor DNA binding domain

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Thyroid hormone receptor mutations found in renal clear cell carcinomas alter corepressor release and reveal helix 12 as key determinant of corepressor specificity

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New insights into the functions and regulation of the transcriptional corepressors SMRT and N-CoR

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Nuclear receptors: one big family

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SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis

12 July 2018

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Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Response of SMRT (silencing mediator of retinoic acid and thyroid hormone receptor) and N-CoR (nuclear receptor corepressor) corepressors to mitogen-activated protein kinase kinase kinase cascades is determined by alternative mRNA splicing

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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The N-CoR complex enables chromatin remodeler SNF2H to enhance repression by thyroid hormone receptor

12 July 2018

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12 July 2018

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Corepressors: custom tailoring and alterations while you wait

12 July 2018

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12 July 2018

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12 July 2018

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The nuclear receptor corepressors NCoR and SMRT decrease peroxisome proliferator-activated receptor gamma transcriptional activity and repress 3T3-L1 adipogenesis.

12 July 2018

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Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes

12 July 2018

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Alternative mRNA splicing of SMRT creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors

12 July 2018

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Alternative splicing generates multiple SMRT transcripts encoding conserved repressor domains linked to variable transcription factor interaction domains.

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors

12 July 2018

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The role of corepressors in transcriptional regulation by nuclear hormone receptors

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor

12 July 2018

1 reference

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Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

12 July 2018

1 reference

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N-CoR-HDAC corepressor complexes: roles in transcriptional regulation by nuclear hormone receptors

12 July 2018

1 reference

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Regulating the regulators: lysine modifications make their mark

12 July 2018

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12 July 2018

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Minireview: nuclear receptor coactivators--an update

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Nuclear receptors and lipid physiology: opening the X-files

12 July 2018

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The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3

12 July 2018

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The specificity of interactions between nuclear hormone receptors and corepressors is mediated by distinct amino acid sequences within the interacting domains

12 July 2018

1 reference

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Peroxisome proliferator-activated receptor gamma and metabolic disease.

12 July 2018

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Histone methylation versus histone acetylation: new insights into epigenetic regulation

12 July 2018

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Transcriptional coregulators of the nuclear receptor superfamily: coactivators and corepressors.

12 July 2018

1 reference

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An unliganded thyroid hormone receptor causes severe neurological dysfunction

12 July 2018

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Determinants of CoRNR-dependent repression complex assembly on nuclear hormone receptors

12 July 2018

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Corepressors and nuclear hormone receptor function.

12 July 2018

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Understanding nuclear receptor function: from DNA to chromatin to the interphase nucleus

12 July 2018

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Combinatorial roles of the nuclear receptor corepressor in transcription and development

12 July 2018

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Identification of a nuclear domain with deacetylase activity.

12 July 2018

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Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3

12 July 2018

1 reference

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The histone deacetylase-3 complex contains nuclear receptor corepressors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

The mechanism of action of thyroid hormones

12 July 2018

1 reference

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Functions of thyroid hormone receptors in mice

12 July 2018

1 reference

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A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPARgamma-mediated adipogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Thyroid hormone-independent interaction between the thyroid hormone receptor beta2 amino terminus and coactivators

12 July 2018

1 reference

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Molecular determinants of nuclear receptor-corepressor interaction

12 July 2018

1 reference

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Unique forms of human and mouse nuclear receptor corepressor SMRT

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Transcriptional silencing is defined by isoform- and heterodimer-specific interactions between nuclear hormone receptors and corepressors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Nuclear hormone receptors and adipogenesis

12 July 2018

1 reference

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Transcriptional repression by the SMRT-mSin3 corepressor: multiple interactions, multiple mechanisms, and a potential role for TFIIB.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

The corepressor N-CoR and its variants RIP13a and RIP13Delta1 directly interact with the basal transcription factors TFIIB, TAFII32 and TAFII70.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Identification and characterization of a novel corepressor interaction region in RVR and Rev-erbA alpha

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Two receptor interacting domains in the nuclear hormone receptor corepressor RIP13/N-CoR

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Two receptor interaction domains in the corepressor, N-CoR/RIP13, are required for an efficient interaction with Rev-erbA alpha and RVR: physical association is dependent on the E region of the orphan receptors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Identification of TRACs (T3 receptor-associating cofactors), a family of cofactors that associate with, and modulate the activity of, nuclear hormone receptors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Cooperative formation of high-order oligomers by retinoid X receptors: an unexpected mode of DNA recognition

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Alternative splicing determines the interaction of SMRT isoforms with nuclear receptor-DNA complexes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Xenopus embryos lacking specific isoforms of the corepressor SMRT develop abnormal heads.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

Determination of nuclear receptor corepressor interactions with the thyroid hormone receptor

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

The nuclear receptor corepressor (N-CoR) contains three isoleucine motifs (I/LXXII) that serve as receptor interaction domains (IDs).

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247966

25 September 2018

ImageJ for microscopy

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.291625

Thyroid hormone and the adipocyte

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22065574

12 December 2020

inferred from PubMed ID database lookup

Two separate NCoR (nuclear receptor corepressor) interaction domains mediate corepressor action on thyroid hormone response elements

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22065574

12 December 2020

inferred from PubMed ID database lookup

SMRT has tissue-specific isoform profiles that include a form containing one CoRNR box

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22065574

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M111.291625

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065574%20AND%20SRC:MED&resulttype=core&format=json

release_vte7oz6dmncdflmugdxwigphwi

16 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vte7oz6dmncdflmugdxwigphwi

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22065574%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference