Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats (Q35647607)

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scientific article published on 17 October 2006

Language	Label	Description	Also known as
English	Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats	scientific article published on 17 October 2006

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

0 references

nicotine withdrawal

1 reference

based on heuristic

inferred from title

author name string

Matthias E Liechti

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Athina Markou

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

language of work or name

0 references

publication date

17 October 2006

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

European Journal of Pharmacology

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Europe PubMed Central

PubMed publication ID

9 August 2017

554

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

2-3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

164-174

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Metabotropic glutamate receptor antagonists: novel therapeutics for nicotine dependence and depression?

1 reference

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An mGluR2/3 antagonist, MGS0039, exerts antidepressant and anxiolytic effects in behavioral models in rats

1 reference

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27 July 2018

A metabotropic glutamate 2/3 receptor antagonist, MGS0039, increases extracellular dopamine levels in the nucleus accumbens shell.

1 reference

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27 July 2018

Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats.

1 reference

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27 July 2018

The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats

1 reference

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Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking

1 reference

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The ups and downs of addiction: role of metabotropic glutamate receptors

1 reference

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MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity.

1 reference

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27 July 2018

Group II metabotropic glutamate receptor antagonists LY341495 and LY366457 increase locomotor activity in mice

1 reference

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27 July 2018

The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice

1 reference

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The origin and neuronal function of in vivo nonsynaptic glutamate.

1 reference

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Neuronal systems underlying behaviors related to nicotine addiction: neural circuits and molecular genetics.

1 reference

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Nicotine dependence: studies with a laboratory model

1 reference

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27 July 2018

Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens

1 reference

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Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system

1 reference

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Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice

1 reference

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27 July 2018

Neural mechanisms underlying nicotine addiction: acute positive reinforcement and withdrawal

1 reference

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27 July 2018

The scientific case that nicotine is addictive.

1 reference

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27 July 2018

The metabotropic glutamate receptors: structure and functions

1 reference

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Persistent behavior at high rates maintained by intravenous self-administration of nicotine.

1 reference

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Signs and symptoms of tobacco withdrawal.

1 reference

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Nicotine maintains robust self-administration in rats on a limited-access schedule

1 reference

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Construct validity of a self-stimulation threshold paradigm: Effects of reward and performance manipulations

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Euphorigenic drugs: effects on the reward pathways of the brain

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Glutamatergic neurotransmission and protein kinase C play a role in neuron-glia communication during the development of methamphetamine-induced psychological dependence

1 reference

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Effects of MPEP on expression of food-, MDMA- or amphetamine-conditioned place preference in rats.

1 reference

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Comparison of c-Fos induction in the brain by the mGlu2/3 receptor antagonist LY341495 and agonist LY354740: evidence for widespread endogenous tone at brain mGlu2/3 receptors in vivo

1 reference

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Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors

1 reference

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The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) rats.

1 reference

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Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats

1 reference

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Effects of MPEP on locomotion, sensitization and conditioned reward induced by cocaine or morphine

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Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent

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Nicotine serves as an effective reinforcer of intravenous drug-taking behavior in human cigarette smokers

1 reference

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Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats

1 reference

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Mecamylamine acutely increases human intravenous nicotine self-administration

1 reference

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Group II metabotropic and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)/kainate glutamate receptors regulate the deficit in brain reward function associated with nicotine withdrawal in rats

1 reference

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Morphine conditioned reward is inhibited by MPEP, the mGluR5 antagonist

1 reference

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The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity

1 reference

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The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse.

1 reference

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Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1803080

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Nicotine potentiation of brain stimulation reward reversed by DH beta E and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1803080

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Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats

1 reference

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25 September 2018

Long-term potentiation of excitatory inputs to brain reward areas by nicotine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1803080

25 September 2018

Nicotine-induced excitation of midbrain dopamine neurons in vitro involves ionotropic glutamate receptor activation.

1 reference

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25 September 2018

Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects.

1 reference

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25 September 2018

Behavioral and biochemical manifestations of mecamylamine-precipitated nicotine withdrawal in the rat: role of nicotinic receptors in the ventral tegmental area

1 reference

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Blockade of nicotine self-administration with nicotinic antagonists in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1803080

25 September 2018

Dramatic decreases in brain reward function during nicotine withdrawal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1803080

25 September 2018

Nicotine as a reinforcer in human subjects and laboratory animals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1803080

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Neurotransmitter regulation of dopamine neurons in the ventral tegmental area

1 reference

https://pubmed.ncbi.nlm.nih.gov/17113075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine self-administration in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17113075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Putative role of presynaptic alpha7* nicotinic receptors in nicotine stimulated increases of extracellular levels of glutamate and aspartate in the ventral tegmental area

1 reference

https://pubmed.ncbi.nlm.nih.gov/17113075

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EJPHAR.2006.10.011

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

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