Atrial-selective sodium channel block strategy to suppress atrial fibrillation: ranolazine versus propafenone. (Q35650683)

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14 January 2020

title

Atrial-selective sodium channel block strategy to suppress atrial fibrillation: ranolazine versus propafenone (English)

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14 January 2020

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3

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14 January 2020

Charles Antzelevitch

series ordinal

4

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14 January 2020

author name string

Alexander Burashnikov

series ordinal

1

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14 January 2020

Luiz Belardinelli

series ordinal

2

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14 January 2020

language of work or name

English

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publication date

17 October 2011

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Journal of Pharmacology and Experimental Therapeutics

14 January 2020

published in

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14 January 2020

volume

340

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14 January 2020

issue

1

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14 January 2020

page(s)

161-168

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Mechanisms of atrial-selective block of Na⁺ channels by ranolazine: I. Experimental analysis of the use-dependent block

14 January 2020

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Targeting atrioventricular differences in ion channel properties for terminating acute atrial fibrillation in pigs

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How Do Atrial-Selective Drugs Differ From Antiarrhythmic Drugs Currently Used in the Treatment of Atrial Fibrillation?

12 July 2018

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AZD1305 exerts atrial predominant electrophysiological actions and is effective in suppressing atrial fibrillation and preventing its reinduction in the dog

12 July 2018

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New developments in atrial antiarrhythmic drug therapy

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The use of oral ranolazine to convert new or paroxysmal atrial fibrillation: a review of experience with implications for possible "pill in the pocket" approach to atrial fibrillation.

12 July 2018

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Atrial-selective sodium channel block for the treatment of atrial fibrillation.

12 July 2018

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Potent antiarrhythmic effects of chronic amiodarone in canine pulmonary vein sleeve preparations

12 July 2018

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Atrial-selective effects of chronic amiodarone in the management of atrial fibrillation.

12 July 2018

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Can inhibition of IKur promote atrial fibrillation?

12 July 2018

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The effect of ranolazine on maintaining sinus rhythm in patients with resistant atrial fibrillation

12 July 2018

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Atrial-selective sodium channel blockers: do they exist?

12 July 2018

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State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine

12 July 2018

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Long-term safety of a novel antianginal agent in patients with severe chronic stable angina: the Ranolazine Open Label Experience (ROLE).

12 July 2018

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Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties

12 July 2018

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Electrophysiological properties of the propafenone-analogue GE 68 (1-[3-(phenylethyl)-2-benzofuryl]-2-(propylamino)-ethanol) in isolated preparations and ventricular myocytes of guinea-pig hearts.

12 July 2018

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Propafenone: an effective agent for the management of supraventricular arrhythmias

12 July 2018

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Basic concepts in cellular cardiac electrophysiology: Part II: Block of ion channels by antiarrhythmic drugs

12 July 2018

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Electrophysiological effects of propafenone in untreated and propafenone-pretreated guinea-pig atrial and ventricular muscle fibres

12 July 2018

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Effects of WAY-123,398, a New Class III Antiarrhythmic Agent, on Cardiac Refractoriness and Ventricular Fibrillation Threshold in Anesthetized Dogs: A Comparison with UK-68798, E-4031, and dl-Sotalol

12 July 2018

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Class I/B antiarrhythmic property of ranolazine, a novel antianginal agent, in dog and human cardiac preparations.

12 July 2018

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Intrapericardial ranolazine prolongs atrial refractory period and markedly reduces atrial fibrillation inducibility in the intact porcine heart

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Efficacy of ranolazine in patients with chronic angina observations from the randomized, double-blind, placebo-controlled MERLIN-TIMI (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST-Segment Elevation Acute Coronary Syndromes) 36 Tr

25 September 2018

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Ranolazine exerts potent effects on atrial electrical properties and abbreviates atrial fibrillation duration in the intact porcine heart

25 September 2018

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Atrium-selective sodium channel block as a strategy for suppression of atrial fibrillation: differences in sodium channel inactivation between atria and ventricles and the role of ranolazine

25 September 2018

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Role of IKur in controlling action potential shape and contractility in the human atrium: influence of chronic atrial fibrillation

25 September 2018

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25 September 2018

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Antiarrhythmic effects of ranolazine in a guinea pig in vitro model of long-QT syndrome

25 September 2018

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Reinduction of atrial fibrillation immediately after termination of the arrhythmia is mediated by late phase 3 early afterdepolarization-induced triggered activity

25 September 2018

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Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non ST-segment elevation acute coronary syndrome: results from the Metabolic Efficiency With Ranolazine for Less

25 September 2018

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12 December 2020

Propafenone inhibition of human atrial myocyte repolarizing currents

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12 December 2020

Comparison of effectiveness and safety of ranolazine versus amiodarone for preventing atrial fibrillation after coronary artery bypass grafting

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12 December 2020

Rate-dependent effects of the class III antiarrhythmic drug almokalant on refractoriness in the pig

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12 December 2020

How Do Atrial-Selective Drugs Differ From Antiarrhythmic Drugs Currently Used in the Treatment of Atrial Fibrillation?

1 reference

12 December 2020

Identifiers

DOI

10.1124/JPET.111.186395

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005044%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

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14 January 2020

PubMed publication ID

22005044

1 reference