Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells. (Q35650970)

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17 January 2020

title

Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells (English)

1 reference

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17 January 2020

9

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Caius Radu

11

1 reference

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17 January 2020

8

David Baltimore

1 reference

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17 January 2020

10

Antoni Ribas

1 reference

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17 January 2020

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Jerome A Zack

1 reference

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17 January 2020

1

Dimitrios N Vatakis

1 reference

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17 January 2020

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Sohn G Kim

1 reference

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17 January 2020

author name string

Richard C Koya

2

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17 January 2020

Christopher C Nixon

3

1 reference

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17 January 2020

Liu Wei

4

1 reference

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17 January 2020

Patricia Avancena

6

1 reference

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17 January 2020

Gregory Bristol

7

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17 January 2020

Zoran Galic

12

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17 January 2020

language of work or name

English

0 references

publication date

28 November 2011

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

17 January 2020

published in

1 reference

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17 January 2020

volume

108

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17 January 2020

issue

51

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17 January 2020

page(s)

E1408-16

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T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia

17 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Transplantation of mouse HSCs genetically modified to express a CD4-restricted TCR results in long-term immunity that destroys tumors and initiates spontaneous autoimmunity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Functional human antigen-specific T cells produced in vitro using retroviral T cell receptor transfer into hematopoietic progenitors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Extrathymic generation of tumor-specific T cells from genetically engineered human hematopoietic stem cells via Notch signaling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Cancer regression in patients after transfer of genetically engineered lymphocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Long-term in vivo provision of antigen-specific T cell immunity by programming hematopoietic stem cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission tomography.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Adoptive-cell-transfer therapy for the treatment of patients with cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Tumors as elusive targets of T-cell-based active immunotherapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Adoptive immunotherapy: engineering T cell responses as biologic weapons for tumor mass destruction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Targeting tumours with genetically enhanced T lymphocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

T-cell-receptor gene therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of t cell-mediated vitiligo.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Use of the 2A sequence from foot-and-mouth disease virus in the generation of retroviral vectors for gene therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Long-term human hematopoiesis in the SCID-hu mouse

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Principles of tumor immunosurveillance and implications for immunotherapy

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115050108

Reprogramming T lymphocytes for melanoma adoptive immunotherapy by T-cell receptor gene transfer with lentiviral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115050108

CD8+ T-cell memory in tumor immunology and immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115050108

Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115050108

Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115050108

A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115050108

Quantitative PET reporter gene imaging of CD8+ T cells specific for a melanoma-expressed self-antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115050108

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Immune-cell lineage commitment: translation from mice to humans

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251070

Preparation and Maintenance of SCID-hu Mice for HIV Research

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22123951

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Improving T cell therapy for cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22123951

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The anti-tumor activity of IL-12: mechanisms of innate immunity that are model and dose dependent

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22123951

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1115050108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22123951%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1 reference

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17 January 2020

PubMed publication ID

22123951

1 reference