Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma (Q35652021)

9 August 2017

title

Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma (English)

1 reference

9 August 2017

main subject

neoplastic stem cells

1 reference

Craig D Peacock

1

1 reference

9 August 2017

Qiuju Wang

2

1 reference

9 August 2017

Gregory S Gesell

3

1 reference

9 August 2017

Ian M Corcoran-Schwartz

4

1 reference

9 August 2017

Evan Jones

5

1 reference

9 August 2017

Jynho Kim

6

1 reference

9 August 2017

Wendy L Devereux

7

1 reference

9 August 2017

Jonathan T Rhodes

8

1 reference

9 August 2017

Carol A Huff

9

1 reference

9 August 2017

Philip A Beachy

10

1 reference

9 August 2017

D Neil Watkins

11

1 reference

9 August 2017

William Matsui

12

1 reference

9 August 2017

language of work or name

English

0 references

publication date

27 February 2007

1 reference

Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

published in

1 reference

9 August 2017

volume

104

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9 August 2017

issue

10

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9 August 2017

page(s)

4048-4053

1 reference

Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

9 August 2017

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1 reference

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Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

12 July 2018

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12 July 2018

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Activation of the hedgehog pathway in a subset of lung cancers

12 July 2018

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Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms

12 July 2018

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Communicating with Hedgehogs

12 July 2018

1 reference

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Hedgehog signalling in prostate regeneration, neoplasia and metastasis

12 July 2018

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12 July 2018

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Hedgehog signalling in foregut malignancy

12 July 2018

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12 July 2018

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Novel lipid modifications of secreted protein signals

12 July 2018

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Characterization of clonogenic multiple myeloma cells

12 July 2018

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

12 July 2018

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Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

12 July 2018

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Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

12 July 2018

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Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

12 July 2018

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Patched acts catalytically to suppress the activity of Smoothened

12 July 2018

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Gli and hedgehog in cancer: tumours, embryos and stem cells.

12 July 2018

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Multiple myeloma: evolving genetic events and host interactions

12 July 2018

1 reference

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Hedgehog signaling in animal development: paradigms and principles

12 July 2018

1 reference

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A mouse model for medulloblastoma and basal cell nevus syndrome

12 July 2018

2 references

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12 July 2018

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Stem cells, cancer, and cancer stem cells

21 January 2018

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Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node

12 July 2018

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The Hedgehog and Wnt signalling pathways in cancer

12 July 2018

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The developmental biology of brain tumors.

12 July 2018

1 reference

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Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805487

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805487

Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

12 July 2018

1 reference

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Altered neural cell fates and medulloblastoma in mouse patched mutants

12 July 2018

1 reference

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Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo

12 July 2018

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Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

12 July 2018

1 reference

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Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID-beta2m-/- repopulating cells

25 September 2018

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Medulloblastoma growth inhibition by hedgehog pathway blockade

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805487

Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells

25 September 2018

1 reference

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Self-renewal versus differentiation, a job for the mighty morphogens

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17360475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fluorescence imaging of multiple myeloma cells in a clinically relevant SCID/NOD in vivo model: biologic and clinical implications

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17360475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0611682104

1 reference

9 August 2017

0 references

1 reference

9 August 2017

1 reference