A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors (Q35652789)

9 August 2017

A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors (English)

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Correction for Scott et al., A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors

9 August 2017

phase I clinical trial

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corrigendum / erratum

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author

Anthony T. Papenfuss

11

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9 August 2017

Terrance G Johns

23

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Gerd Ritter

18

object named as

Gerd Ritter

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9 August 2017

24

Lloyd J Old

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9 August 2017

1

Andrew M Scott

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9 August 2017

21

Antony W Burgess

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9 August 2017

2

Fook-Thean Lee

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9 August 2017

13

Wendie Hopkins

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9 August 2017

8

Carmel Murone

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9 August 2017

9

Timothy H Saunder

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9 August 2017

Niall Tebbutt

3

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9 August 2017

Rebecca Herbertson

4

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9 August 2017

Sanjeev S Gill

5

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9 August 2017

Zhanqi Liu

6

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9 August 2017

Effie Skrinos

7

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9 August 2017

Bridget Chappell

10

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9 August 2017

Aurora M T Poon

12

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9 August 2017

Fiona E Smyth

14

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9 August 2017

Duncan MacGregor

15

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9 August 2017

Lawrence M Cher

16

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9 August 2017

Achim A Jungbluth

17

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9 August 2017

Martin W Brechbiel

19

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9 August 2017

Roger Murphy

20

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9 August 2017

Eric W Hoffman

22

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9 August 2017

language of work or name

English

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publication date

28 February 2007

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Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

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9 August 2017

104

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9 August 2017

10

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9 August 2017

4071-4076

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Mechanisms of cutaneous toxicities to EGFR inhibitors.

9 August 2017

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27 July 2018

1 reference

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Phase I study of the humanised anti-EGFR monoclonal antibody matuzumab (EMD 72000) combined with gemcitabine in advanced pancreatic cancer

27 July 2018

1 reference

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27 July 2018

1 reference

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The antitumor monoclonal antibody 806 recognizes a high-mannose form of the EGF receptor that reaches the cell surface when cells over-express the receptor

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1 reference

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Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR

27 July 2018

1 reference

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Critical update and emerging trends in epidermal growth factor receptor targeting in cancer

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1 reference

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Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor

27 July 2018

1 reference

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Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478.

27 July 2018

1 reference

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Generation of anti-idiotype antibodies for application in clinical immunotherapy laboratory analyses

27 July 2018

1 reference

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Inhibitors of epidermal-growth-factor receptors: a review of clinical research with a focus on non-small-cell lung cancer

27 July 2018

1 reference

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A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer

27 July 2018

1 reference

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A monoclonal antibody recognizing human cancers with amplification/overexpression of the human epidermal growth factor receptor

27 July 2018

1 reference

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Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805701

Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor.

27 July 2018

1 reference

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Construction, production, and characterization of humanized anti-Lewis Y monoclonal antibody 3S193 for targeted immunotherapy of solid tumors

27 July 2018

1 reference

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Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin.

27 July 2018

1 reference

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Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials

27 July 2018

1 reference

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IDEC-C2B8 (Rituximab) anti-CD20 monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin's lymphoma

27 July 2018

1 reference

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A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805701

Specific targeting of a mutant, activated FGF receptor found in glioblastoma using a monoclonal antibody

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805701

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805701

Immunogenetics of human cell surface differentiation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805701

Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805701

Quantitative analysis of antibody localization in human metastatic colon cancer: a phase I study of monoclonal antibody A33.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805701

Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805701

Treatment of high-grade glioma patients with the humanized anti-epidermal growth factor receptor (EGFR) antibody h-R3: report from a phase I/II trial.

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611693104

Novel monoclonal antibody specific for the de2-7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611693104

Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611693104

Safety, pharmacokinetics, and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer

21 January 2018

1 reference

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The EGFR as a target for anticancer therapy--focus on cetuximab

21 January 2018

1 reference

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Specific targeting, biodistribution, and lack of immunogenicity of chimeric anti-GD3 monoclonal antibody KM871 in patients with metastatic melanoma: results of a phase I trial.

25 September 2018

1 reference

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Targeting of renal cell carcinoma with iodine-131-labeled chimeric monoclonal antibody G250

25 September 2018

1 reference

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Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model

15 November 2018

1 reference

12 December 2020

OLINDA/EXM: the second-generation personal computer software for internal dose assessment in nuclear medicine

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12 December 2020

Monoclonal antibody therapy of cancer

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Pharmacokinetics of cetuximab after administration of escalating single dosing and weekly fixed dosing in patients with solid tumors

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12 December 2020

Serological analysis of human anti-human antibody responses in colon cancer patients treated with repeated doses of humanized monoclonal antibody A33

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12 December 2020

Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma

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Antibody targeting in metastatic colon cancer: a phase I study of monoclonal antibody F19 against a cell-surface protein of reactive tumor stromal fibroblasts

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Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer

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Identifiers

DOI

10.1073/PNAS.0611693104

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9 August 2017

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9 August 2017

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