Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice. (Q35655010)

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scientific article published on 6 June 2015

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English	Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice.	scientific article published on 6 June 2015

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16 February 2020

Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice (English)

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16 February 2020

1

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16 February 2020

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16 February 2020

Victor A. Gault

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Victor A Gault

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16 February 2020

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Srividya Vasu

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16 February 2020

publication date

6 June 2015

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16 February 2020

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16 February 2020

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16 February 2020

https://scigraph.springernature.com/pub.10.1007/s00125-015-3653-1

0 references

Effects of beta-cell rest on beta-cell function: a review of clinical and preclinical data

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

Inhibition of insulin secretion as a new drug target in the treatment of metabolic disorders

1 reference

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Sulfonylurea induced beta-cell apoptosis in cultured human islets

1 reference

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21 January 2018

Evidence for beneficial effects of compromised gastric inhibitory polypeptide action in obesity-related diabetes and possible therapeutic implications.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

Predominant role of GIP in the development of a metabolic syndrome-like phenotype in female Wistar rats submitted to forced catch-up growth.

1 reference

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21 January 2018

The role of gut hormones in glucose homeostasis

1 reference

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21 January 2018

Improved beta-cell survival and reduced insulitis in a type 1 diabetic rat model after treatment with a beta-cell-selective K(ATP) channel opener.

1 reference

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21 January 2018

Chemical ablation of gastric inhibitory polypeptide receptor action by daily (Pro3)GIP administration improves glucose tolerance and ameliorates insulin resistance and abnormalities of islet structure in obesity-related diabetes

1 reference

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21 January 2018

(Pro(3))GIP[mPEG]: novel, long-acting, mPEGylated antagonist of gastric inhibitory polypeptide for obesity-diabetes (diabesity) therapy.

1 reference

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21 January 2018

Biological and functional characteristics of a novel low-molecular weight antagonist of glucose-dependent insulinotropic polypeptide receptor, SKL-14959, in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

Antagonism of gastric inhibitory polypeptide (GIP) by palmitoylation of GIP analogues with N- and C-terminal modifications improves obesity and metabolic control in high fat fed mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

Biology of incretins: GLP-1 and GIP

1 reference

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21 January 2018

GIP(6-30amide) contains the high affinity binding region of GIP and is a potent inhibitor of GIP1-42 action in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

Evaluation of the antidiabetic activity of DPP IV resistant N-terminally modified versus mid-chain acylated analogues of glucose-dependent insulinotropic polypeptide.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose intolerance and associated disturbances in mice fed high-fat and cafeteria diets.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

The C-terminal extension of exendin-4 provides additional metabolic stability when added to GLP-1, while there is minimal effect of truncating exendin-4 in anaesthetized pigs.

1 reference

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21 January 2018

A novel long-acting glucose-dependent insulinotropic peptide analogue: enhanced efficacy in normal and diabetic rodents

1 reference

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21 January 2018

The circadian clock and behavior.

1 reference

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21 January 2018

Modulation of adipoinsular axis in prediabetic zucker diabetic fatty rats by diazoxide

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

Induction of beta-cell rest by a Kir6.2/SUR1-selective K(ATP)-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

Exposure to chronic high glucose induces beta-cell apoptosis through decreased interaction of glucokinase with mitochondria: downregulation of glucokinase in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

Chronic suppression of insulin by diazoxide alters the activities of key enzymes regulating hepatic gluconeogenesis in Zucker rats

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

Fatty acids, obesity, and insulin resistance: time for a reevaluation

1 reference

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21 January 2018

A DPP-IV-resistant triple-acting agonist of GIP, GLP-1 and glucagon receptors with potent glucose-lowering and insulinotropic actions in high-fat-fed mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

The novel GLP-1-gastrin dual agonist ZP3022 improves glucose homeostasis and increases β-cell mass without affecting islet number in db/db mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents.

1 reference

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21 January 2018

A novel glucagon-like peptide-1 (GLP-1)/glucagon hybrid peptide with triple-acting agonist activity at glucose-dependent insulinotropic polypeptide, GLP-1, and glucagon receptors and therapeutic potential in high fat-fed mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3653-1

21 January 2018

Chronic Reduction of GIP Secretion Alleviates Obesity and Insulin Resistance Under High-Fat Diet Conditions

1 reference

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21 January 2018

Integrating advances in insulin into clinical practice: Advances In insulin formulations.

1 reference

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12 December 2020

based on heuristic

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Abnormal plasma glucose and insulin responses in heterozygous lean (ob/+) mice

1 reference

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12 December 2020

based on heuristic

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Studies with the mutation, diabetes, in the mouse

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https://pubmed.ncbi.nlm.nih.gov/26048235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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