Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans (Q35669097)

9 August 2017

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans (English)

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9 August 2017

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Marina Caskey

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Mark J Cameron

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object named as

Mark J Cameron

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9 August 2017

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Ralph M Steinman

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9 August 2017

Christine Trumpfheller

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object named as

Christine Trumpfheller

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9 August 2017

François Lefebvre

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9 August 2017

Abdelali Filali-Mouhim

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9 August 2017

Jean-Philippe Goulet

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9 August 2017

Elias K Haddad

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9 August 2017

Gaëlle Breton

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9 August 2017

Sarah Pollak

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9 August 2017

Irina Shimeliovich

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9 August 2017

Angela Duque-Alarcon

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9 August 2017

Li Pan

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9 August 2017

Annette Nelkenbaum

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9 August 2017

Andres M Salazar

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9 August 2017

Sarah J Schlesinger

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Rafick P Sékaly

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9 August 2017

language of work or name

English

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publication date

7 November 2011

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Journal of Experimental Medicine

9 August 2017

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9 August 2017

208

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2357-2366

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describes a project that uses

9 August 2017

limma

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22 June 2022

https://europepmc.org/article/PMC/3256967

based on heuristic

inferred from PubMed Central ID database lookup

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A diverse range of gene products are effectors of the type I interferon antiviral response

27 July 2018

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Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulo

27 July 2018

1 reference

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Vaccine adjuvants: putting innate immunity to work

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256967

Vaccines and the future of human immunology

27 July 2018

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Regulation of inflammasome activity.

27 July 2018

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Dissecting interferon-induced transcriptional programs in human peripheral blood cells

27 July 2018

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The role of inflammasomes in the immunostimulatory effects of particulate vaccine adjuvants.

27 July 2018

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Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses

27 July 2018

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Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant

27 July 2018

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Inflammasome recognition of influenza virus is essential for adaptive immune responses

27 July 2018

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Inflammasomes: guardians of cytosolic sanctity

27 July 2018

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New horizons in adjuvants for vaccine development

27 July 2018

1 reference

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Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

27 July 2018

1 reference

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Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

27 July 2018

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Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.

27 July 2018

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Vaccines: correlates of vaccine-induced immunity

27 July 2018

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Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action

27 July 2018

1 reference

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Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses

27 July 2018

1 reference

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

27 July 2018

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Adjusting batch effects in microarray expression data using empirical Bayes methods

27 July 2018

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Translating innate immunity into immunological memory: implications for vaccine development

27 July 2018

1 reference

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Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256967

Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256967

Bioconductor: open software development for computational biology and bioinformatics

27 July 2018

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Inferences, questions and possibilities in Toll-like receptor signalling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256967

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256967

Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256967

A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma

27 July 2018

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

25 September 2018

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Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256967

Direct Stimulation of T Cells by Type I IFN Enhances the CD8+ T Cell Response during Cross-Priming

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22065672

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A pathway analysis of poly(I:C)-induced global gene expression change in human peripheral blood mononuclear cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22065672

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20111171

1 reference

9 August 2017

1 reference

9 August 2017

1 reference