Molecular genetic studies of complex phenotypes (Q35676062)

9 August 2017

title

Molecular genetic studies of complex phenotypes (English)

1 reference

9 August 2017

Ali J Marian

1

1 reference

9 August 2017

publication date

31 August 2011

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9 August 2017

published in

Translational Research

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9 August 2017

volume

159

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9 August 2017

issue

2

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9 August 2017

page(s)

64-79

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Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1.

9 August 2017

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27 July 2018

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Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations

27 July 2018

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Strategic approaches to unraveling genetic causes of cardiovascular diseases

27 July 2018

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Comparison of three targeted enrichment strategies on the SOLiD sequencing platform

27 July 2018

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A rare variant in MYH6 is associated with high risk of sick sinus syndrome

27 July 2018

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K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension

27 July 2018

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9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

27 July 2018

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Initial impact of the sequencing of the human genome

27 July 2018

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Mapping copy number variation by population-scale genome sequencing

27 July 2018

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Network medicine: a network-based approach to human disease

27 July 2018

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Targeted next-generation sequencing of a 12.5 Mb homozygous region reveals ANO10 mutations in patients with autosomal-recessive cerebellar ataxia

27 July 2018

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Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

27 July 2018

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Diversity of human copy number variation and multicopy genes

27 July 2018

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A map of human genome variation from population-scale sequencing

27 July 2018

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Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome

27 July 2018

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Biological, clinical and population relevance of 95 loci for blood lipids

27 July 2018

1 reference

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Genomewide association studies and assessment of the risk of disease

27 July 2018

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Whole-genome sequencing of a single proband together with linkage analysis identifies a Mendelian disease gene

27 July 2018

1 reference

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Hypertrophic cardiomyopathy: from genetics to treatment

27 July 2018

1 reference

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Missing heritability and strategies for finding the underlying causes of complex disease

27 July 2018

1 reference

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A method and server for predicting damaging missense mutations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Genetics of lipid disorders

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Analysis of genetic inheritance in a family quartet by whole-genome sequencing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Comprehensive survey of SNPs in the Affymetrix exon array using the 1000 Genomes dataset

27 July 2018

1 reference

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Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Rare variants create synthetic genome-wide associations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Nature's genetic gradients and the clinical phenotype

27 July 2018

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Exome sequencing identifies the cause of a mendelian disorder

27 July 2018

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A highly annotated whole-genome sequence of a Korean individual

27 July 2018

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Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip

27 July 2018

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Common vs. rare allele hypotheses for complex diseases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Avoiding the high Bonferroni penalty in genome-wide association studies

27 July 2018

1 reference

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Next-generation DNA sequencing techniques

27 July 2018

1 reference

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The genetic structure and history of Africans and African Americans

27 July 2018

1 reference

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Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Common variants at 30 loci contribute to polygenic dyslipidemia

27 July 2018

1 reference

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The diploid genome sequence of an Asian individual

27 July 2018

1 reference

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Genes mirror geography within Europe

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Common and rare variants in multifactorial susceptibility to common diseases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Mapping and sequencing of structural variation from eight human genomes

27 July 2018

1 reference

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The complete genome of an individual by massively parallel DNA sequencing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

The diploid genome sequence of an individual human

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Genome-wide mapping of modifier chromosomal loci for human hypertrophic cardiomyopathy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

27 July 2018

1 reference

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A common allele on chromosome 9 associated with coronary heart disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

A common variant on chromosome 9p21 affects the risk of myocardial infarction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Complement factor H polymorphism in age-related macular degeneration

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

The allelic architecture of human disease genes: common disease-common variant... or not?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Patterns of linkage disequilibrium in the human genome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Linkage disequilibrium in humans: models and data

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Are rare variants responsible for susceptibility to complex diseases?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Linkage disequilibrium in the human genome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Initial sequencing and analysis of the human genome

27 July 2018

1 reference

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The Sequence of the Human Genome

27 July 2018

1 reference

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The future of genetic studies of complex human diseases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Genetic dissection of complex traits

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Molecular genetic and functional characterization implicate muscle-restricted coiled-coil gene (MURC) as a causal gene for familial dilated cardiomyopathy

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Familial hypercholesterolemias: prevalence, genetics, diagnosis and screening recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Experimental evidence supports a sex-specific selective sieve in mitochondrial genome evolution.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Targeted next-generation sequencing for the molecular genetic diagnostics of cardiomyopathies.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Genetics. Revealing the dark matter of the genome.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Genomics. 1000 Genomes Project gives new map of genetic diversity

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Uncovering the roles of rare variants in common disease through whole-genome sequencing

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Blood pressure and human genetic variation in the general population

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Genetic diagnosis by whole exome capture and massively parallel DNA sequencing

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Genome-wide association study identifies eight loci associated with blood pressure

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Coronary Artery Disease-Associated Locus on Chromosome 9p21 and Early Markers of Atherosclerosis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Polymorphic Y chromosomes harbor cryptic variation with manifold functional consequences.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Genome sequencing in microfabricated high-density picolitre reactors

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Increase in power of transmission-disequilibrium tests for quantitative traits

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Mapping genes by drift-generated linkage disequilibrium

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

A picture worth 1000 Genomes

23 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

A first-generation linkage disequilibrium map of human chromosome 22

7 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259530

Mapping Genes through the Use of Linkage Disequilibrium Generated by Genetic Drift: ‘Drift Mapping’ in Small Populations with No Demographic Expansion

7 December 2018

2 references

Crossref

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.08.001

7 January 2021

https://pubmed.ncbi.nlm.nih.gov/22243791

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.TRSL.2011.08.001

1 reference

9 August 2017

1 reference

9 August 2017

1 reference