Inhibiting the Mammalian target of rapamycin blocks the development of experimental cerebral malaria (Q35676305)

9 August 2017

Inhibiting the Mammalian target of rapamycin blocks the development of experimental cerebral malaria (English)

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9 August 2017

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Munir Akkaya

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Tuan M Tran

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Tuan M Tran

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Jeff Skinner

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Jeff Skinner

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Louis H. Miller

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Louis H Miller

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9 August 2017

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Susan K Pierce

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9 August 2017

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Geoffrey T Hart

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9 August 2017

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Michael Waisberg

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Takele Yazew

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9 August 2017

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Emile B Gordon

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Mirna Pena

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9 August 2017

Severin Zinöcker

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9 August 2017

Chen-Feng Qi

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9 August 2017

language of work or name

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2 June 2015

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9 August 2017

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e00725

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describes a project that uses

9 August 2017

limma

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22 June 2022

https://europepmc.org/article/PMC/4453009

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inferred from PubMed Central ID database lookup

cites work

Pathogenic CD8+ T cells in experimental cerebral malaria

1 reference

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Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression

12 July 2018

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A comprehensive evaluation of rodent malaria parasite genomes and gene expression

12 July 2018

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The systemic pathology of cerebral malaria in African children

12 July 2018

1 reference

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Damage to the blood-brain barrier during experimental cerebral malaria results from synergistic effects of CD8+ T cells with different specificities

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

Real-time imaging reveals the dynamics of leukocyte behaviour during experimental cerebral malaria pathogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

Integrating canonical and metabolic signalling programmes in the regulation of T cell responses

12 July 2018

1 reference

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Cerebral malaria in children: using the retina to study the brain

12 July 2018

1 reference

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Stuck in a rut? Reconsidering the role of parasite sequestration in severe malaria syndromes

12 July 2018

1 reference

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Distinct patterns of cerebral extravasation by Evans blue and sodium fluorescein in rats

12 July 2018

1 reference

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Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins

12 July 2018

1 reference

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Brain microvessel cross-presentation is a hallmark of experimental cerebral malaria

12 July 2018

1 reference

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Comparison of parasite sequestration in uncomplicated and severe childhood Plasmodium falciparum malaria

12 July 2018

1 reference

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Neuroimmunological blood brain barrier opening in experimental cerebral malaria

12 July 2018

1 reference

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Cerebral malaria: we have come a long way

12 July 2018

1 reference

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Diagnosing severe falciparum malaria in parasitaemic African children: a prospective evaluation of plasma PfHRP2 measurement

12 July 2018

1 reference

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Cerebral malaria: mysteries at the blood-brain barrier

12 July 2018

1 reference

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A rapid and robust tri-color flow cytometry assay for monitoring malaria parasite development

12 July 2018

1 reference

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Cerebral malaria pathogenesis: revisiting parasite and host contributions.

12 July 2018

1 reference

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The role of animal models for research on severe malaria

12 July 2018

1 reference

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Testing in mice the hypothesis that melanin is protective in malaria infections

12 July 2018

1 reference

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Role of interleukin-10 in malaria: focusing on coinfection with lethal and nonlethal murine malaria parasites

12 July 2018

1 reference

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Regulation of immune responses by mTOR.

12 July 2018

1 reference

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The neuropathology of fatal cerebral malaria in malawian children

12 July 2018

1 reference

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Targeting FK506 binding proteins to fight malarial and bacterial infections: current advances and future perspectives.

12 July 2018

1 reference

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Molecular correlates of experimental cerebral malaria detectable in whole blood

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

mTORC2 regulates neutrophil chemotaxis in a cAMP- and RhoA-dependent fashion

12 July 2018

1 reference

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Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

12 July 2018

1 reference

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Accumulation of Plasmodium berghei-infected red blood cells in the brain is crucial for the development of cerebral malaria in mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

12 July 2018

1 reference

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Immunity to malaria: more questions than answers

12 July 2018

1 reference

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Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria.

12 July 2018

1 reference

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Immunological processes in malaria pathogenesis.

12 July 2018

1 reference

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Genomic organisation and expression of BCL6 in murine B-cell lymphomas

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

Systemic endothelial activation occurs in both mild and severe malaria. Correlating dermal microvascular endothelial cell phenotype and soluble cell adhesion molecules with disease severity

12 July 2018

1 reference

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Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria.

12 July 2018

1 reference

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Indicators of life-threatening malaria in African children

12 July 2018

1 reference

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Induction of pro-inflammatory mediators in Plasmodium berghei infected BALB/c mice breaks blood-brain-barrier and leads to cerebral malaria in an IL-12 dependent manner.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

Granzyme B expression by CD8+ T cells is required for the development of experimental cerebral malaria.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

Coincident parasite and CD8 T cell sequestration is required for development of experimental cerebral malaria.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

Complement factors C1q, C3 and C5 in brain and serum of mice with cerebral malaria

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

Blood-brain barrier permeability using tracers and immunohistochemistry.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

Platelet accumulation in brain microvessels in fatal pediatric cerebral malaria.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

On the pathogenic role of brain-sequestered alphabeta CD8+ T cells in experimental cerebral malaria.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

Induction of heme oxygenase-1 after hyperosmotic opening of the blood-brain barrier

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4453009

25 September 2018

Identifiers

DOI

10.1128/MBIO.00725-15

1 reference

9 August 2017

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9 August 2017

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