Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells (Q35677075)

9 August 2017

title

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells (English)

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9 August 2017

main subject

chronic myeloid leukemia

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Maeva Dufies

1

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9 August 2017

Arnaud Jacquel

2

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9 August 2017

Nathalie Belhacene

3

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9 August 2017

Guillaume Robert

4

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9 August 2017

Thomas Cluzeau

5

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9 August 2017

Fréderic Luciano

6

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9 August 2017

Jill Patrice Cassuto

7

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9 August 2017

Sophie Raynaud

8

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9 August 2017

Patrick Auberger

9

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9 August 2017

language of work or name

English

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publication date

1 November 2011

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9 August 2017

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9 August 2017

volume

2

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9 August 2017

issue

11

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9 August 2017

page(s)

874-885

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Targeting Axl and Mer kinases in cancer

9 August 2017

cites work

1 reference

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The novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of nonreceptor kinases: implications for therapy

27 July 2018

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27 July 2018

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PMA up-regulates the transcription of Axl by AP-1 transcription factor binding to TRE sequences via the MAPK cascade in leukaemia cells

27 July 2018

1 reference

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors

27 July 2018

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Signalling and functional diversity within the Axl subfamily of receptor tyrosine kinases

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance.

27 July 2018

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27 July 2018

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Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase

27 July 2018

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Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

27 July 2018

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axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

27 July 2018

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27 July 2018

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Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation

25 September 2018

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Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors.

25 September 2018

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Regulation of megakaryocytic differentiation of K562 cells by FosB, a member of the Fos family of AP-1 transcription factors

25 September 2018

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Receptor tyrosine kinase AXL is induced by chemotherapy drugs and overexpression of AXL confers drug resistance in acute myeloid leukemia

25 September 2018

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Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

25 September 2018

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JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis

25 September 2018

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Differential requirements for ERK1/2 and P38 MAPK activation by thrombin in T cells. Role of P59Fyn and PKCepsilon.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259992

Selective induction of apoptosis in Philadelphia chromosome-positive chronic myelogenous leukemia cells by an inhibitor of BCR–ABL tyrosine kinase, CGP 57148

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22141136

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl-positive human leukemia cells to apoptosis due to antileukemic drugs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22141136

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.360

0 references

PMC publication ID

3259992

1 reference

9 August 2017

1 reference