An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway (Q35682245)

9 August 2017

An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway (English)

1 reference

9 August 2017

Yu Zhang

1

1 reference

PubMed ID

21131978

9 August 2017

Maria Jasin

series ordinal

2

1 reference

9 August 2017

5 December 2010

1 reference

Nature Structural & Molecular Biology

9 August 2017

1 reference

9 August 2017

18

1 reference

9 August 2017

1

1 reference

9 August 2017

80-84

1 reference

https://scigraph.springernature.com/pub.10.1038/nsmb.1940

9 August 2017

0 references

cites work

CtIP promotes microhomology-mediated alternative end joining during class-switch recombination

1 reference

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Origin of chromosomal translocations in lymphoid cancer

27 July 2018

1 reference

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Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Complex landscapes of somatic rearrangement in human breast cancer genomes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Recent insights into the formation of RAG-induced chromosomal translocations.

27 July 2018

1 reference

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Role of mammalian Mre11 in classical and alternative nonhomologous end joining

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

27 July 2018

1 reference

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Mechanisms promoting translocations in editing and switching peripheral B cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

The mechanism of human nonhomologous DNA end joining

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

IgH class switching and translocations use a robust non-classical end-joining pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Chromatin structural elements and chromosomal translocations in leukemia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Alternative pathways for the repair of RAG-induced DNA breaks

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

A model of oncogenic rearrangements: differences between chromosomal translocation mechanisms and simple double-strand break repair

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Isolation of scid pre-B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Human CtIP promotes DNA end resection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261752

Chromosomal translocation mechanisms at intronic alu elements in mammalian cells

25 September 2018

1 reference

Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination

31 March 2020

1 reference

A system for stable expression of short interfering RNAs in mammalian cells

31 March 2020

1 reference

Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.1940

1 reference

PubMed ID

21131978

Dimensions Publication ID

9 August 2017

0 references

1 reference

9 August 2017

1 reference

PubMed ID

21131978