Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress. (Q35691127)

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27 December 2019

title

Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress (English)

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27 December 2019

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6

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27 December 2019

Giovanni G. Camici

1

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27 December 2019

Markus Bachschmid

4

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27 December 2019

Massimo Volpe

9

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27 December 2019

Francesco Cosentino

12

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27 December 2019

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Thomas F Lüscher

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27 December 2019

author name string

Marzia Schiavoni

2

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27 December 2019

Pietro Francia

3

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27 December 2019

Ines Martin-Padura

5

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27 December 2019

Felix C Tanner

7

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27 December 2019

Piergiuseppe Pelicci

8

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27 December 2019

Piero Anversa

10

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27 December 2019

language of work or name

English

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publication date

14 March 2007

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number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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volume

104

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27 December 2019

page(s)

5217-5222

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27 December 2019

issue

12

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describes a project that uses

27 December 2019

ImageQuant

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

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27 July 2018

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The p66shc adaptor protein controls oxidative stress response and life span in mammals

27 July 2018

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Endothelial dysfunction in a model of hyperglycemia and hyperinsulinemia.

27 July 2018

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Bilirubin is an antioxidant of possible physiological importance

27 July 2018

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Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin-dependent) diabetes mellitus

27 July 2018

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Heme oxygenase-2 deficiency contributes to diabetes-mediated increase in superoxide anion and renal dysfunction

27 July 2018

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Gene delivery of Tim44 reduces mitochondrial superoxide production and ameliorates neointimal proliferation of injured carotid artery in diabetic rats

25 September 2018

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Suppressive effects of cacao liquor polyphenols (CLP) on LDL oxidation and the development of atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic rabbits

25 September 2018

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Absence of heme oxygenase-1 exacerbates myocardial ischemia/reperfusion injury in diabetic mice

25 September 2018

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Endothelial function: cardiac events

25 September 2018

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Diabetes induces p66shc gene expression in human peripheral blood mononuclear cells: relationship to oxidative stress.

25 September 2018

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Deletion of p66shc gene protects against age-related endothelial dysfunction

25 September 2018

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p66ShcA modulates tissue response to hindlimb ischemia.

25 September 2018

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The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.

25 September 2018

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Heme oxygenase-1 prevents superoxide anion-associated endothelial cell sloughing in diabetic rats

25 September 2018

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Heme oxygenase-1 attenuates glucose-mediated cell growth arrest and apoptosis in human microvessel endothelial cells

25 September 2018

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High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species

25 September 2018

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Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet.

25 September 2018

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A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.

25 September 2018

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Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

25 September 2018

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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

25 September 2018

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25 September 2018

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Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency

25 September 2018

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Not all Shc's roads lead to Ras

25 September 2018

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Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus

25 September 2018

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Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus.

25 September 2018

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Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0609656104

Postoperative sensitivity in Class I composite resin restorations in vivo

21 January 2018

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12 December 2020

Deletion of p66Shc longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress

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12 December 2020

Thiol Compounds Interact with Nitric Oxide in Regulating Heme Oxygenase-1 Induction in Endothelial Cells

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12 December 2020

High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0609656104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17360381%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

0 references

1 reference

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27 December 2019

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