Ubiquitin and breast cancer (Q35691563)

9 August 2017

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title

Ubiquitin and breast cancer (English)

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9 August 2017

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Tomohiko Ohta

1

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PubMed ID

15021895

9 August 2017

Mamoru Fukuda

series ordinal

2

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PubMed ID

15021895

9 August 2017

language of work or name

English

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publication date

1 March 2004

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9 August 2017

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9 August 2017

23

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9 August 2017

11

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9 August 2017

2079-2088

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207371

9 August 2017

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cites work

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Skp2 is oncogenic and overexpressed in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Molecular mechanisms underlying ErbB2/HER2 action in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

BRCA1 is associated with the centrosome during mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Cyclin E and survival in patients with breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

How the cyclin became a cyclin: regulated proteolysis in the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

CUL-4A is critical for early embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Enforced expression of CUL-4A interferes with granulocytic differentiation and exit from the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Brca1 controls homology-directed DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

The xeroderma pigmentosum group E gene product DDB2 is a specific target of cullin 4A in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Modulation of estrogen receptor alpha function and stability by tamoxifen and a critical amino acid (Asp-538) in helix 12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Ubiquitin enters the new millennium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Ligand-specific regulation of proteasome-mediated proteolysis of estrogen receptor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Estrogen induction of the cyclin D1 promoter: involvement of a cAMP response-like element

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

BRCA1 is a component of the RNA polymerase II holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Gene expression profiling predicts clinical outcome of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

BRCA1-independent ubiquitination of FANCD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Degradation of Transcription Repressor ZBRK1 through the Ubiquitin-Proteasome Pathway Relieves Repression of Gadd45a upon DNA Damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

ErbB2 degradation mediated by the co-chaperone protein CHIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

Ubiquitination of the rat uterine estrogen receptor: dependence on estradiol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

inferred from DOI database lookup

7 January 2021

based on heuristic

The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207371

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1207371

1 reference

9 August 2017

1 reference

PubMed ID

15021895