Study of genotypic and phenotypic HIV-1 dynamics of integrase mutations during raltegravir treatment: a refined analysis by ultra-deep 454 pyrosequencing (Q35694729)

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scientific article published on 11 January 2012

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English	Study of genotypic and phenotypic HIV-1 dynamics of integrase mutations during raltegravir treatment: a refined analysis by ultra-deep 454 pyrosequencing	scientific article published on 11 January 2012

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scholarly article

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Europe PubMed Central

PubMed publication ID

9 August 2017

Study of genotypic and phenotypic HIV-1 dynamics of integrase mutations during raltegravir treatment: a refined analysis by ultra-deep 454 pyrosequencing (English)

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Europe PubMed Central

PubMed publication ID

9 August 2017

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based on heuristic

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Francesca Ceccherini-Silberstein

19

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Francesca Ceccherini-Silberstein

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9 August 2017

Carlo Federico Perno

18

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Carlo Federico Perno

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9 August 2017

Andrea Antinori

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Andrea Antinori

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9 August 2017

Roberta D'Arrigo

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Roberta D'Arrigo

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9 August 2017

Daniele Armenia

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Daniele Armenia

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9 August 2017

Pasquale Narciso

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Pasquale Narciso

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9 August 2017

Valeria Micheli

9

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Valeria Micheli

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9 August 2017

Giuliano Rizzardini

13

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Giuliano Rizzardini

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9 August 2017

Bianca Bruzzone

10

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Bianca Bruzzone

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9 August 2017

3

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Lavinia Fabeni

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9 August 2017

Fernanda Scopelliti

8

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Fernanda Scopelliti

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9 August 2017

Liesbeth Van Wesenbeeck

7

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Liesbeth Van Wesenbeeck

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9 August 2017

Lieven J Stuyver

17

object named as

Lieven Stuyver

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9 August 2017

Ina Vandenbroucke

2

object named as

Ina Vandenbroucke

1 reference

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9 August 2017

5

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Valeria Cento

1 reference

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9 August 2017

Jeroen Aerssens

12

object named as

Jeroen Aerssens

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9 August 2017

author name string

Herwig Van Marck

4

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9 August 2017

Sergio Lo Caputo

11

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9 August 2017

Valerio Tozzi

14

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9 August 2017

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publication date

11 January 2012

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9 August 2017

Journal of Infectious Diseases

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9 August 2017

205

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9 August 2017

4

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9 August 2017

557-567

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9 August 2017

HIV type-1 drug resistance in treatment-naive patients monitored using minority species assays: a systematic review and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Update of the drug resistance mutations in HIV-1: December 2010.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Analysis of low-frequency mutations associated with drug resistance to raltegravir before antiretroviral treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

HIV-1 integrase sequence variability in antiretroviral naïve patients and in triple-class experienced patients subsequently treated with raltegravir.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

HIV-1 V3 envelope deep sequencing for clinical plasma specimens failing in phenotypic tropism assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Prevalence and clinical significance of HIV drug resistance mutations by ultra-deep sequencing in antiretroviral-naïve subjects in the CASTLE study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Low-frequency HIV-1 drug resistance mutations can be clinically significant but must be interpreted with caution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Pre-existing minority drug-resistant HIV-1 variants, adherence, and risk of antiretroviral treatment failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Early emergence of raltegravir resistance mutations in patients receiving HAART salvage regimens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Loss of raltegravir susceptibility by human immunodeficiency virus type 1 is conferred via multiple nonoverlapping genetic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Minority variants associated with transmitted and acquired HIV-1 nonnucleoside reverse transcriptase inhibitor resistance: implications for the use of second-generation nonnucleoside reverse transcriptase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Natural polymorphisms of human immunodeficiency virus type 1 integrase and inherent susceptibilities to a panel of integrase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Minor Variant Detection at Different Template Concentrations in HIV-1 Phenotypic and Genotypic Tropism Testing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Estimating maximum likelihood phylogenies with PhyML.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Characterization and structural analysis of HIV-1 integrase conservation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Dynamic patterns of human immunodeficiency virus type 1 integrase gene evolution in patients failing raltegravir-based salvage therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Emerging pharmacology: inhibitors of human immunodeficiency virus integration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Raltegravir with optimized background therapy for resistant HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Analysis of natural sequence variation and covariation in human immunodeficiency virus type 1 integrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

The discovery of raltegravir, an integrase inhibitor for the treatment of HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

A pyrosequencing-tailored nucleotide barcode design unveils opportunities for large-scale sample multiplexing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Rapid and durable antiretroviral effect of the HIV-1 Integrase inhibitor raltegravir as part of combination therapy in treatment-naive patients with HIV-1 infection: results of a 48-week controlled study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Characterization of mutation spectra with ultra-deep pyrosequencing: application to HIV-1 drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

DNA bar coding and pyrosequencing to identify rare HIV drug resistance mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Rationale and uses of a public HIV drug-resistance database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

27 July 2018

Viruses as quasispecies: biological implications

1 reference

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27 July 2018

Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

1 reference

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27 July 2018

Bias in template-to-product ratios in multitemplate PCR

1 reference

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27 July 2018

Low level of the K103N HIV-1 above a threshold is associated with virological failure in treatment-naive individuals undergoing efavirenz-containing therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

25 September 2018

Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

25 September 2018

Evolution patterns of raltegravir-resistant mutations after integrase inhibitor interruption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

25 September 2018

Secondary integrase resistance mutations found in HIV-1 minority quasispecies in integrase therapy-naive patients have little or no effect on susceptibility to integrase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

25 September 2018

High frequency of integrase Q148R minority variants in HIV-infected patients naive of integrase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266134

25 September 2018

Strand transfer inhibitors of HIV-1 integrase: bringing IN a new era of antiretroviral therapy

1 reference

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25 September 2018

Low-frequency K103N strengthens the impact of transmitted drug resistance on virologic responses to first-line efavirenz or nevirapine-based highly active antiretroviral therapy

1 reference

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25 September 2018

A combined genotypic and phenotypic human immunodeficiency virus type 1 recombinant virus assay for the reverse transcriptase and integrase genes

1 reference

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25 September 2018

Evolution of raltegravir resistance during therapy.

1 reference

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25 September 2018

Low-abundance drug-resistant viral variants in chronically HIV-infected, antiretroviral treatment-naive patients significantly impact treatment outcomes

1 reference

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25 September 2018

Minority quasispecies of drug-resistant HIV-1 that lead to early therapy failure in treatment-naive and -adherent patients

1 reference

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25 September 2018

Clade-specific HIV-1 integrase polymorphisms do not reduce raltegravir and elvitegravir phenotypic susceptibility

1 reference

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25 September 2018

Inferring evolutionary trees with PAUP*.

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25 September 2018

Preexisting resistance to nonnucleoside reverse-transcriptase inhibitors predicts virologic failure of an efavirenz-based regimen in treatment-naive HIV-1-infected subjects

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25 September 2018

A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum Likelihood

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25 September 2018

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10.1093/INFDIS/JIR821

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Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

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Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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