Engineering islets: lessons from stem cells and embryonic development (Q35725808)

9 August 2017

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title

Engineering islets: lessons from stem cells and embryonic development (English)

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9 August 2017

Michelle J Doyle

1

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9 August 2017

Lori Sussel

series ordinal

2

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9 August 2017

publication date

1 March 2004

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Endocrinology and Metabolism Clinics of North America

9 August 2017

published in

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9 August 2017

volume

33

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9 August 2017

issue

1

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9 August 2017

page(s)

149-62, x

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Stem/progenitor cells derived from adult tissues: potential for the treatment of diabetes mellitus

9 August 2017

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Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells

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Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells

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Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons.

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beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

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Genes expressed in the developing endocrine pancreas and their importance for stem cell and diabetes research

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Involvement of hepatocyte nuclear factor 3 in endoderm differentiation of embryonic stem cells

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Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice

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Islet growth and development in the adult

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7 January 2021

Linear correlation between beta-cell mass and body weight throughout the lifespan in Lewis rats: role of beta-cell hyperplasia and hypertrophy

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7 January 2021

Pancreatic beta-cell growth and survival--a role in obesity-linked type 2 diabetes?

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7 January 2021

Induction of beta-cell neogenesis by islet injury

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7 January 2021

Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas

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7 January 2021

Pancreatic stem cells

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7 January 2021

Early pattern of differentiation in the human pancreas

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7 January 2021

In vitro cultivation of human islets from expanded ductal tissue

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7 January 2021

Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells

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7 January 2021

Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes

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7 January 2021

Differentiation and proliferation of endocrine cells in the regenerating rat pancreas after 90% pancreatectomy

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7 January 2021

In Vivo Cell Transformation: Neogenesis of Beta Cells from Pancreatic Ductal Cells

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7 January 2021

Nestin-expressing cells in the pancreatic islets of Langerhans

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7 January 2021

Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas

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7 January 2021

Nestin expression in pancreatic stellate cells and angiogenic endothelial cells

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Nestin expression in pancreatic exocrine cell lineages.

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7 January 2021

Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture

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7 January 2021

In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion

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7 January 2021

Pancreatic cell lineage analyses in mice

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7 January 2021

Little evidence of transdifferentiation of bone marrow-derived cells into pancreatic beta cells

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7 January 2021

Bone marrow-derived stem cells initiate pancreatic regeneration.

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7 January 2021

Little evidence for developmental plasticity of adult hematopoietic stem cells

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7 January 2021

Pluripotency of mesenchymal stem cells derived from adult marrow

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Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

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Experimental conversion of liver to pancreas

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In vitro trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells

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7 January 2021

Molecular development of the pancreatic β cell: implications for cell replacement therapy

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7 January 2021

Gene expression cascades in pancreatic development

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7 January 2021

Developmental aspects of the endocrine pancreas

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7 January 2021

Purification and distribution of ghrelin: the natural endogenous ligand for the growth hormone secretagogue receptor

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7 January 2021

Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion

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7 January 2021

Expression of Ghrelin and of the GH Secretagogue Receptor by Pancreatic Islet Cells and Related Endocrine Tumors

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7 January 2021

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7 January 2021

Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development

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7 January 2021

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7 January 2021

Notochord repression of endodermal Sonic hedgehog permits pancreas development

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7 January 2021

TGF-beta plays a key role in morphogenesis of the pancreatic islets of Langerhans by controlling the activity of the matrix metalloproteinase MMP-2

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7 January 2021

Hedgehog signaling in pancreas development

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7 January 2021

Notch signalling controls pancreatic cell differentiation

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7 January 2021

Control of endodermal endocrine development by Hes-1

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7 January 2021

Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas.

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7 January 2021

Intercellular signals regulating pancreas development and function

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7 January 2021

In-vitro differentiation of pancreatic beta-cells

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7 January 2021

Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis

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7 January 2021

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

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7 January 2021

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

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7 January 2021

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

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7 January 2021

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

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7 January 2021

Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice

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7 January 2021

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5

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7 January 2021

The mojo of methylation

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7 January 2021

Insulin-promoter-factor 1 is required for pancreas development in mice

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7 January 2021

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

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7 January 2021

The beta cell transcription factors and development of the pancreas

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7 January 2021

Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells

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7 January 2021

Analysis of insulin-producing cells during in vitro differentiation from feeder-free embryonic stem cells

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7 January 2021

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

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7 January 2021

10.1016/S0889-8529(03)00100-2

Identifiers

DOI

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9 August 2017

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