IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection (Q35737807)

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scientific article published on 28 December 2011

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English	IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection	scientific article published on 28 December 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 August 2017

IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection (English)

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Europe PubMed Central

PubMed publication ID

10 August 2017

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10 August 2017

object named as

Jean Langhorne

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object named as

Werner Muller

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author name string

Ana Paula Freitas do Rosário

1

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Europe PubMed Central

PubMed publication ID

10 August 2017

Tracey Lamb

2

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Europe PubMed Central

PubMed publication ID

10 August 2017

Philip Spence

3

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Europe PubMed Central

PubMed publication ID

10 August 2017

Robin Stephens

4

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Europe PubMed Central

PubMed publication ID

10 August 2017

Agathe Lang

5

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Europe PubMed Central

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10 August 2017

Axel Roers

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Europe PubMed Central

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10 August 2017

language of work or name

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publication date

28 December 2011

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Europe PubMed Central

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10 August 2017

Journal of Immunology

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Europe PubMed Central

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10 August 2017

188

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Europe PubMed Central

PubMed publication ID

10 August 2017

3

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Europe PubMed Central

PubMed publication ID

10 August 2017

1178-1190

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Europe PubMed Central

PubMed publication ID

10 August 2017

TGF-β signaling via Smad4 drives IL-10 production in effector Th1 cells and reduces T-cell trafficking in EAE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

IL-27 and IL-21 are associated with T cell IL-10 responses in human visceral leishmaniasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

IL-21 is an immune activator that also mediates suppression via IL-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo

1 reference

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12 July 2018

Effector memory Th1 CD4 T cells are maintained in a mouse model of chronic malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection

1 reference

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12 July 2018

Plasmodium vivax: induction of CD4+CD25+FoxP3+ regulatory T cells during infection are directly associated with level of circulating parasites.

1 reference

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12 July 2018

The regulation of IL-10 production by immune cells

1 reference

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Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion

1 reference

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Bordetella evades the host immune system by inducing IL-10 through a type III effector, BopN

1 reference

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Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection

1 reference

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12 July 2018

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

1 reference

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12 July 2018

IL-27 regulates IL-10 and IL-17 from CD4+ cells in nonhealing Leishmania major infection

1 reference

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12 July 2018

Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10-secreting Th1 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Nonredundant roles for B cell-derived IL-10 in immune counter-regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Mechanisms of foxp3+ T regulatory cell-mediated suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Identification and characterization of IL-10/IFN-gamma-producing effector-like T cells with regulatory function in human blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Advances in understanding the anti-inflammatory properties of IL-27.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children

1 reference

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12 July 2018

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Interleukin-10 production by effector T cells: Th1 cells show self control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Interleukin-10 determines viral clearance or persistence in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1beta), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12(p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy con

1 reference

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12 July 2018

Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

1 reference

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A new mathematical model for relative quantification in real-time RT-PCR

1 reference

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12 July 2018

Interleukin-10 and the interleukin-10 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

Development of Th1-type immune responses requires the type I cytokine receptor TCCR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

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ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272378

12 July 2018

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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B lymphocyte-specific, Cre-mediated mutagenesis in mice

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Plasmodium chabaudi chabaudi: differential susceptibility of gene-targeted mice deficient in IL-10 to an erythrocytic-stage infection

1 reference

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Interleukin-10 downregulates Mycobacterium tuberculosis-induced Th1 responses and CTLA-4 expression

1 reference

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Interleukin-10-deficient mice develop chronic enterocolitis

1 reference

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RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

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Human cord blood CD4+CD25hi regulatory T cells suppress prenatally acquired T cell responses to Plasmodium falciparum antigens

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Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions.

1 reference

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25 September 2018

Gradual decline in malaria-specific memory T cell responses leads to failure to maintain long-term protective immunity to Plasmodium chabaudi AS despite persistence of B cell memory and circulating antibody.

1 reference

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Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells

1 reference

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Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system.

1 reference

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T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation

1 reference

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A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

1 reference

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Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

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25 September 2018

Low plasma concentrations of interleukin-10 in severe malarial anaemia compared with cerebral and uncomplicated malaria.

1 reference

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25 September 2018

Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes

1 reference

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25 September 2018

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1 reference

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25 September 2018

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1 reference

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Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

1 reference

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1 reference

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CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22205023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22205023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10

1 reference

https://pubmed.ncbi.nlm.nih.gov/22205023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22205023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1102755

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

ResearchGate publication ID

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