Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10-secreting Th1 cells. (Q42024502)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19635862%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10-secreting Th1 cells (English)

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3 February 2020

1

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3 February 2020

Johan Verhagen

4

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3 February 2020

author name string

Kirsty S Nicolson

2

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3 February 2020

Heather B Streeter

3

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3 February 2020

Catherine A Sabatos-Peyton

5

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3 February 2020

David J Morgan

6

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3 February 2020

David C Wraith

7

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3 February 2020

language of work or name

English

0 references

publication date

27 July 2009

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Journal of Experimental Medicine

3 February 2020

published in

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3 February 2020

volume

206

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issue

8

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page(s)

1755-1767

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Identification and characterization of IL-10/IFN-gamma-producing effector-like T cells with regulatory function in human blood

3 February 2020

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5 June 2018

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5 June 2018

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5 June 2018

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IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

5 June 2018

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Expression of ICOS in vivo defines CD4+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10.

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

5 June 2018

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Low avidity recognition of self-antigen by T cells permits escape from central tolerance.

5 June 2018

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5 June 2018

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Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

5 June 2018

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Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering

5 June 2018

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5 June 2018

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B7H1-Ig fusion protein activates the CD4+ IFN-gamma receptor+ type 1 T regulatory subset through IFN-gamma-secreting Th1 cells.

16 June 2018

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IL-2 overcomes the unresponsiveness but fails to reverse the regulatory function of antigen-induced T regulatory cells.

17 August 2018

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Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells

17 August 2018

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Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.

17 August 2018

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Peripheral deletion of antigen-reactive T cells in oral tolerance.

17 August 2018

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IL-10–producing and naturally occurring CD4+ Tregs: limiting collateral damage

17 August 2018

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Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction.

21 January 2018

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Role for IL-10 in suppression mediated by peptide-induced regulatory T cells in vivo

21 January 2018

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Activation of MAP kinase p38 is critical for the cell-cycle-controlled suppressor function of regulatory T cells

3 November 2018

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Glucocorticoids down‐regulate dendritic cell function in vitro and in vivo

21 January 2018

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Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells

21 January 2018

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12 December 2020

Negative feedback mechanism suppresses interleukin-12 production by antigen-presenting cells interacting with T helper 2 cells

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12 December 2020

Mucosal tolerance and suppression of collagen-induced arthritis (CIA) induced by nasal inhalation of synthetic peptide 184-198 of bovine type II collagen (CII) expressing a dominant T cell epitope

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12 December 2020

IL-12 induces human T cells secreting IL-10 with IFN-gamma

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12 December 2020

Immunoregulatory role of IL-10 during superantigen-induced hyporesponsiveness in vivo

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12 December 2020

Effect of interleukin-10 on dendritic cell maturation and function

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12 December 2020

Differences between responses of naive and activated T cells to anergy induction

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12 December 2020

Peptide-induced T cell regulation of experimental autoimmune encephalomyelitis: a role for IL-10

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12 December 2020

IL-2 activation of STAT5 enhances production of IL-10 from human cytotoxic regulatory T cells, HOZOT

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12 December 2020

Naive T cells are resistant to anergy induction by anti-CD3 antibodies

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12 December 2020

Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: influence of MHC binding affinity

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T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis

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12 December 2020

Identifiers

DOI

10.1084/JEM.20082118

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19635862%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19635862%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

19635862

1 reference