Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells (Q35747758)

10 August 2017

Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells (English)

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10 August 2017

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Clare L Kirkpatrick

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Howard Riezman

object named as

Howard Riezman

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author name string

Sharon Epstein

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10 August 2017

Guillaume A Castillon

3

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10 August 2017

Manuel Muñiz

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10 August 2017

Isabelle Riezman

5

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10 August 2017

Fabrice P A David

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10 August 2017

Claes B Wollheim

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10 August 2017

30 December 2011

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Journal of Lipid Research

10 August 2017

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10 August 2017

53

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3

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10 August 2017

412-420

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describes a project that uses

10 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3276464/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

ER stress and its functional link to mitochondria: role in cell survival and death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

The yeast p24 complex regulates GPI-anchored protein transport and quality control by monitoring anchor remodeling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Yeast lipid analysis and quantification by mass spectrometry

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Ceramide in stress response

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Ceramide synthases: roles in cell physiology and signaling

27 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

27 July 2018

https://api.crossref.org/works/10.1194%2FJLR.M022186

Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

p24 family type 1 transmembrane proteins are required for insulin biosynthesis and secretion in pancreatic beta-cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Orm family proteins mediate sphingolipid homeostasis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Divergent effects of PERK and IRE1 signaling on cell viability

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

GRP78, but Not Protein-disulfide Isomerase, Partially Reverses Hyperglycemia-induced Inhibition of Insulin Synthesis and Secretion in Pancreatic {beta}-Cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

The role for endoplasmic reticulum stress in diabetes mellitus

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Mammalian GPI-anchored proteins require p24 proteins for their efficient transport from the ER to the plasma membrane

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Signal integration in the endoplasmic reticulum unfolded protein response

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Sphingoid base is required for translation initiation during heat stress in Saccharomyces cerevisiae

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

The ins and outs of sphingolipid synthesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Lip1p: a novel subunit of acyl-CoA ceramide synthase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Increased ubiquitin-dependent degradation can replace the essential requirement for heat shock protein induction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Ceramide in apoptosis: an overview and current perspectives

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

The uracil transporter Fur4p associates with lipid rafts

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Functional profiling of the Saccharomyces cerevisiae genome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Angiostatin effects on endothelial cells mediated by ceramide and RhoA.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Deletion of yeast p24 genes activates the unfolded protein response

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Specific requirements for the ER to Golgi transport of GPI-anchored proteins in yeast

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Hydroxylation of Saccharomyces cerevisiae ceramides requires Sur2p and Scs7p

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Fah1p, a Saccharomyces cerevisiae cytochrome b5 fusion protein, and its Arabidopsis thaliana homolog that lacks the cytochrome b5 domain both function in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Ceramide synthesis enhances transport of GPI-anchored proteins to the Golgi apparatus in yeast.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Endocytosis is required for the growth of vacuolar H(+)-ATPase-defective yeast: identification of six new END genes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Cloning and characterization of LCB1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276464

Thematic review series: sphingolipids. New insights into sphingolipid metabolism and function in budding yeast

27 July 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

Distinct roles for de novo versus hydrolytic pathways of sphingolipid biosynthesis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

Raft partitioning of the yeast uracil permease during trafficking along the endocytic pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

Sphingolipids are required for the stable membrane association of glycosylphosphatidylinositol-anchored proteins in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

Protection of C. elegans from anoxia by HYL-2 ceramide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

Isolation and complete sequence of CBR, a gene encoding a putative cytochrome b reductase in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

Acute nutrient regulation of the unfolded protein response and integrated stress response in cultured rat pancreatic islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

Involvement of chronic stresses in rat islet and INS-1 cell glucotoxicity induced by intermittent high glucose.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

The group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

Membrane biogenesis and the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M022186

The mammalian ABC transporter ABCA1 induces lipid-dependent drug sensitivity in yeast

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22210926

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Roles for Sphingolipid Biosynthesis in Mediation of Specific Programs of the Heat Stress Response Determined through Gene Expression Profiling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22210926

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1194/JLR.M022186

1 reference

10 August 2017

1 reference

10 August 2017

1 reference