Aberrant Expression and Activation of the Thrombin Receptor Protease-Activated Receptor-1 Induces Cell Proliferation and Motility in Human Colon Cancer Cells (Q35749110)

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scientific article published on May 1, 2003

Language	Label	Description	Also known as
English	Aberrant Expression and Activation of the Thrombin Receptor Protease-Activated Receptor-1 Induces Cell Proliferation and Motility in Human Colon Cancer Cells	scientific article published on May 1, 2003

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells (English)

1 reference

Europe PubMed Central

10 August 2017

Aberrant Expression and Activation of the Thrombin Receptor Protease-Activated Receptor-1 Induces Cell Proliferation and Motility in Human Colon Cancer Cells (English)

1 reference

10.1016/S0002-9440(10)64283-6

https://api.crossref.org/works/10.1016/S0002-9440(10)64283-6

26 December 2023

1 reference

based on heuristic

inferred from title

neoplastic gene expression regulation

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707033

26 December 2023

author name string

Dalila Darmoul

1

1 reference

Europe PubMed Central

10 August 2017

Valérie Gratio

2

1 reference

Europe PubMed Central

10 August 2017

Hélène Devaud

3

1 reference

Europe PubMed Central

10 August 2017

Thérèse Lehy

4

1 reference

Europe PubMed Central

10 August 2017

Marc Laburthe

5

1 reference

Europe PubMed Central

10 August 2017

language of work or name

0 references

publication date

1 May 2003

1 reference

Europe PubMed Central

10 August 2017

full work available at URL

http://ajp.amjpathol.org/article/S0002944010642836/pdf

Portable Document Format

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707033

26 December 2023

https://europepmc.org/articles/PMC1851194

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707033

26 December 2023

https://europepmc.org/articles/PMC1851194?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707033

26 December 2023

https://api.elsevier.com/content/article/PII:S0002944010642836?httpAccept=text/xml

1 reference

10.1016/S0002-9440(10)64283-6

https://api.crossref.org/works/10.1016/S0002-9440(10)64283-6

26 December 2023

https://api.elsevier.com/content/article/PII:S0002944010642836?httpAccept=text/plain

1 reference

10.1016/S0002-9440(10)64283-6

https://api.crossref.org/works/10.1016/S0002-9440(10)64283-6

26 December 2023

The American Journal of Pathology

1 reference

Europe PubMed Central

10 August 2017

162

1 reference

Europe PubMed Central

10 August 2017

5

1 reference

Europe PubMed Central

10 August 2017

1503-1513

1 reference

Europe PubMed Central

10 August 2017

The serine proteinase thrombin promotes migration of human renal carcinoma cells by a PKA-dependent mechanism

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27 July 2018

International Union of Pharmacology. XXVIII. Proteinase-activated receptors

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Expression of the thrombin receptor PAR-1 correlates with tumour cell differentiation of pancreatic adenocarcinoma in vitro

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Insulin, insulin-like growth factors and colon cancer: a review of the evidence

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Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2

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Molecular basis for the relationship between thrombosis and cancer

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Expression of protease-activated receptor 1 in oral squamous cell carcinoma

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27 July 2018

The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways

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Proteinase-activated receptors.

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The genetic basis of colorectal cancer: insights into critical pathways of tumorigenesis

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The role of polypeptide growth factors in human carcinomas: new targets for a novel pharmacological approach.

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27 July 2018

PAR3 is a cofactor for PAR4 activation by thrombin

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27 July 2018

Protein kinases C-gamma and -delta are involved in insulin-like growth factor I-induced migration of colonic epithelial cells

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A dual thrombin receptor system for platelet activation

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27 July 2018

Thrombin receptor overexpression in malignant and physiological invasion processes

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Proteinase-activated receptors: novel mechanisms of signaling by serine proteases.

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27 July 2018

Cloning and characterization of human protease-activated receptor 4

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27 July 2018

Thrombin receptor activation results in calcium signaling and protein kinase C-dependent stimulation of DNA synthesis in HEp-2g laryngeal carcinoma cells

1 reference

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27 July 2018

Angiogenesis in colorectal cancer

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27 July 2018

Protease-activated receptor 3 is a second thrombin receptor in humans

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27 July 2018

Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

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27 July 2018

Lessons from hereditary colorectal cancer

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27 July 2018

Genomic cloning and characterization of the human thrombin receptor gene. Structural similarity to the proteinase activated receptor-2 gene

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27 July 2018

Thrombin enhances the adhesion and migration of human colon adenocarcinoma cells via increased beta 3-integrin expression on the tumour cell surface and their inhibition by the snake venom peptide, rhodostomin

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27 July 2018

Biology and biochemistry of proteinases in tumor invasion.

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Hepatocyte growth factor/scatter factor modulates intestinal epithelial cell proliferation and migration

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27 July 2018

Molecular cloning of a potential proteinase activated receptor

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27 July 2018

Solid tumor cells express functional "tethered ligand" thrombin receptor.

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Inhibition of the platelet-aggregating activity of two human adenocarcinomas of the colon and an anaplastic murine tumor with a specific thrombin inhibitor, dansylarginine N-(3-ethyl-1,5-pentanediyl)amide

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Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

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Coagulative system activation and fibrinolytic system inhibition activities arise from tumoral draining vein in colon carcinoma

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Characterization of platelet aggregation induced by human colon adenocarcinoma cells and its inhibition by snake venom peptides, trigramin and rhodostomin

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Neurotensin and a non-peptide neurotensin receptor antagonist control human colon cancer cell growth in cell culture and in cells xenografted into nude mice

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Thrombin increases the metastatic potential of tumor cells

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The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity

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12 December 2020

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Characterization of a common VIP-PACAP receptor in human small intestinal epithelium

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12 December 2020

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Internalization and recycling of activated thrombin receptors

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12 December 2020

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inferred from PubMed ID database lookup

Cellular localization of enzymatically active thrombin in intact human tissues by hirudin binding

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12 December 2020

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Pre- and postoperative state of coagulation and fibrinolysis in plasma of patients with benign and malignant colorectal disease--a preliminary study

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12 December 2020

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Evaluation of proteinase-activated receptor-1 (PAR1) agonists and antagonists using a cultured cell receptor desensitization assay: activation of PAR2 by PAR1-targeted ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/12707033

12 December 2020

based on heuristic

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Identifiers

10.1016/S0002-9440(10)64283-6

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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