Down-regulation of programmed cell death 4 (PDCD4) is associated with aromatase inhibitor resistance and a poor prognosis in estrogen receptor-positive breast cancer. (Q35752065)

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scientific article published on 31 May 2015

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English	Down-regulation of programmed cell death 4 (PDCD4) is associated with aromatase inhibitor resistance and a poor prognosis in estrogen receptor-positive breast cancer.	scientific article published on 31 May 2015

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16 February 2020

Down-regulation of programmed cell death 4 (PDCD4) is associated with aromatase inhibitor resistance and a poor prognosis in estrogen receptor-positive breast cancer (English)

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16 February 2020

estrogen-receptor positive breast cancer

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16 February 2020

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16 February 2020

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Zhike Chen

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16 February 2020

Yate-Ching Yuan

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16 February 2020

Hei Jason Chan

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16 February 2020

Shiuan Chen

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16 February 2020

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31 May 2015

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16 February 2020

Breast Cancer Research and Treatment

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16 February 2020

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16 February 2020

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16 February 2020

29-39

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16 February 2020

Mechanisms of endocrine resistance in breast cancer: an overview of the proposed roles of noncoding RNA

1 reference

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Aromatase deficiency in a Chinese adult man caused by novel compound heterozygous CYP19A1 mutations: effects of estrogen replacement therapy on the bone, lipid, liver and glucose metabolism.

1 reference

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Aberrations in translational regulation are associated with poor prognosis in hormone receptor-positive breast cancer

1 reference

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The importance of HER2 signaling in the tumor-initiating cell population in aromatase inhibitor-resistant breast cancer

1 reference

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AKT-aro and HER2-aro, models for de novo resistance to aromatase inhibitors; molecular characterization and inhibitor response studies

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Estrogenic regulation of S6K1 expression creates a positive regulatory loop in control of breast cancer cell proliferation

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A kinome-wide screen identifies the insulin/IGF-I receptor pathway as a mechanism of escape from hormone dependence in breast cancer

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MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1α expression

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MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligand

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The role of microRNA-128a in regulating TGFbeta signaling in letrozole-resistant breast cancer cells

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Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors

1 reference

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Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion.

1 reference

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The tumour suppressor Pdcd4: recent advances in the elucidation of function and regulation

1 reference

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2 October 2017

Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells

1 reference

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2 October 2017

Genome-wide analysis of aromatase inhibitor-resistant, tamoxifen-resistant, and long-term estrogen-deprived cells reveals a role for estrogen receptor

1 reference

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2 October 2017

MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene

1 reference

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2 October 2017

Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion

1 reference

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2 October 2017

Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells

1 reference

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Alterations in the expression of PDCD4 in ductal carcinoma of the breast.

1 reference

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MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

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S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

1 reference

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Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis

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Involvement of programmed cell death 4 in transforming growth factor-beta1-induced apoptosis in human hepatocellular carcinoma

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Long-term estradiol deprivation in breast cancer cells up-regulates growth factor signaling and enhances estrogen sensitivity

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1 reference

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1 reference

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Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death

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Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase

1 reference

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1 reference

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1 reference

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1007/S10549-015-3446-8

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Europe PubMed Central

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16 February 2020

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16 February 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26026468%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

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