Absence of perforin expression confers axonal protection despite demyelination. (Q35762252)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17112732%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

title

Absence of perforin expression confers axonal protection despite demyelination (English)

1 reference

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22 December 2019

1

1 reference

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22 December 2019

Jaimie D Adelson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17112732%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Moses Rodriguez

3

1 reference

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22 December 2019

author name string

Charles L Howe

1

1 reference

PubMed ID

17112732

10 August 2017

Jaimie D Adelson

2

1 reference

PubMed ID

17112732

10 August 2017

Moses Rodriguez

3

1 reference

10 August 2017

16 November 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17112732%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

published in

Neurobiology of Disease

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22 December 2019

volume

25

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22 December 2019

issue

2

1 reference

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22 December 2019

page(s)

354-359

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17112732%20AND%20SRC:MED&resulttype=core&format=json

Addressing the mysteries of perforin function.

22 December 2019

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation

2 October 2017

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Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction

2 October 2017

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Axonal loss results in spinal cord atrophy, electrophysiological abnormalities and neurological deficits following demyelination in a chronic inflammatory model of multiple sclerosis

2 October 2017

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Axonal loss in multiple sclerosis lesions: magnetic resonance imaging insights into substrates of disability

2 October 2017

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Quantitation of spinal cord demyelination, remyelination, atrophy, and axonal loss in a model of progressive neurologic injury

2 October 2017

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Quantitative assessment of neurologic deficits in a chronic progressive murine model of CNS demyelination.

2 October 2017

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CD4(+) and CD8(+) T cells make discrete contributions to demyelination and neurologic disease in a viral model of multiple sclerosis

2 October 2017

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Oligodendrocyte and axon pathology in clinically silent multiple sclerosis lesions

2 October 2017

1 reference

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Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis

2 October 2017

1 reference

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The immune system preferentially clears Theiler's virus from the gray matter of the central nervous system

2 October 2017

1 reference

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Role of macrophages during Theiler's virus infection

2 October 2017

1 reference

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Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

2 October 2017

1 reference

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Induction of MHC class I genes in neurons

2 October 2017

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Ultrastructural immunohistochemical localization of virus in acute and chronic demyelinating Theiler's virus infection

2 October 2017

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Neurofilament gene expression: a major determinant of axonal caliber

2 October 2017

1 reference

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Immunoglobulins stimulate central nervous system remyelination: electron microscopic and morphometric analysis of proliferating cells

2 October 2017

1 reference

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Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

2 October 2017

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Theiler's virus replication in brain macrophages cultured in vitro

2 October 2017

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Coexpression of class I major histocompatibility antigen and viral RNA in central nervous system of mice infected with Theiler's virus: a model for multiple sclerosis

2 October 2017

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Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination

2 October 2017

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Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes

2 October 2017

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Persistent infection of oligodendrocytes in Theiler's virus‐induced encephalomyelitis

12 July 2018

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Magnetic resonance imaging. Clinical correlation in 64 patients with multiple sclerosis.

12 July 2018

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Preservation of motor function by inhibition of CD8+ virus peptide-specific T cells in Theiler's virus infection

12 July 2018

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CD8-deficient SJL mice display enhanced susceptibility to Theiler's virus infection and increased demyelinating pathology

25 September 2018

1 reference

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Extensive injury of descending neurons demonstrated by retrograde labeling in a virus-induced murine model of chronic inflammatory demyelination

25 September 2018

1 reference

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CNS cell populations are protected from virus-induced pathology by distinct arms of the immune system

25 September 2018

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Imaging of axonal damage in multiple sclerosis: spatial distribution of magnetic resonance imaging lesions.

25 September 2018

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Differential expression of H-2K and H-2D in the central nervous system of mice infected with Theiler's virus.

25 September 2018

1 reference

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Effect of Demyelination on Conduction in the Central Nervous System

25 September 2018

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12 December 2020

Determinants of conduction velocity in myelinated nerve fibers

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12 December 2020

An electrophysiological study of the postnatal development of the corticospinal system in the macaque monkey

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12 December 2020

Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation

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12 December 2020

Preservation of neurologic function during inflammatory demyelination correlates with axon sparing in a mouse model of multiple sclerosis

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12 December 2020

10.1016/J.NBD.2006.10.001

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17112732%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17112732%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference