Hexim1 sequesters positive transcription elongation factor b from the class II transactivator on MHC class II promoters. (Q35768625)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17088550%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Hexim1 sequesters positive transcription elongation factor b from the class II transactivator on MHC class II promoters (English)

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21 December 2019

2

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21 December 2019

author name string

Jiri Kohoutek

series ordinal

1

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21 December 2019

B Matija Peterlin

series ordinal

3

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21 December 2019

language of work or name

English

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publication date

6 November 2006

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17088550%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

21 December 2019

published in

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21 December 2019

volume

103

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21 December 2019

issue

46

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21 December 2019

page(s)

17349-17354

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Expression of MHC II genes

21 December 2019

cites work

1 reference

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Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb

12 July 2018

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Runx1 binds positive transcription elongation factor b and represses transcriptional elongation by RNA polymerase II: possible mechanism of CD4 silencing

12 July 2018

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Increased HEXIM1 expression during erythroleukemia and neuroblastoma cell differentiation

12 July 2018

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HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b

12 July 2018

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The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1

12 July 2018

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Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat

12 July 2018

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Cdk9 regulates neural differentiation and its expression correlates with the differentiation grade of neuroblastoma and PNET tumors.

12 July 2018

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HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK

12 July 2018

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Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription

12 July 2018

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Elongation by RNA polymerase II: the short and long of it

12 July 2018

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Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure

12 July 2018

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Ablation of the CLP-1 gene leads to down-regulation of the HAND1 gene and abnormality of the left ventricle of the heart and fetal death

12 July 2018

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Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

12 July 2018

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Enhancement of CIITA transcriptional function by ubiquitin

12 July 2018

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CIITA regulates transcription onset viaSer5-phosphorylation of RNA Pol II

12 July 2018

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MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner

12 July 2018

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Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells

12 July 2018

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Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy.

12 July 2018

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Genetic control of MHC class II expression

12 July 2018

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Interferon-gamma-induced chromatin remodeling at the CIITA locus is BRG1 dependent

12 July 2018

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Interaction between P-TEFb and the C-terminal domain of RNA polymerase II activates transcriptional elongation from sites upstream or downstream of target genes

12 July 2018

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7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes

12 July 2018

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The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription

12 July 2018

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Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene.

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1859933

Dendritic cell-specific MHC class II transactivator contains a caspase recruitment domain that confers potent transactivation activity

12 July 2018

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The bare lymphocyte syndrome and the regulation of MHC expression

12 July 2018

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BLIMP-I mediates extinction of major histocompatibility class II transactivator expression in plasma cells

12 July 2018

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Class II transactivator: mastering the art of major histocompatibility complex expression

12 July 2018

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Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection

12 July 2018

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Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta

12 July 2018

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Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA.

12 July 2018

1 reference

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Binding and cooperative interactions between two B cell-specific transcriptional coactivators.

12 July 2018

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Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

12 July 2018

1 reference

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Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb

12 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0603079103

Cyclin T1 expression is regulated by multiple signaling pathways and mechanisms during activation of human peripheral blood lymphocytes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0603079103

Generation of deletion and point mutations with one primer in a single cloning step

21 January 2018

1 reference

12 December 2020

Constitutive expression of MHC class II genes in melanoma cell lines results from the transcription of class II transactivator abnormally initiated from its B cell-specific promoter

1 reference

12 December 2020

Varying functions of specific major histocompatibility class II transactivator promoter III and IV elements in melanoma cell lines

1 reference

12 December 2020

Differentiation of Burkitt lymphoma cells by hexamethylenbisacetamide

1 reference

12 December 2020

Cyclin T1 but not cyclin T2a is induced by a post-transcriptional mechanism in PAMP-activated monocyte-derived macrophages

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0603079103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17088550%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

0 references

1 reference

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21 December 2019

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