Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo (Q35775811)

10 August 2017

Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo (English)

1 reference

10 August 2017

19

Sayda M Elbashir

1 reference

10 August 2017

Donald J Foster

1

1 reference

10 August 2017

Scott Barros

2

1 reference

10 August 2017

Rick Duncan

3

1 reference

10 August 2017

Sarfraz Shaikh

4

1 reference

10 August 2017

William Cantley

5

1 reference

10 August 2017

Amy Dell

6

1 reference

10 August 2017

Elena Bulgakova

7

1 reference

10 August 2017

Jonathan O'Shea

8

1 reference

10 August 2017

Nate Taneja

9

1 reference

10 August 2017

Satya Kuchimanchi

10

1 reference

10 August 2017

Christopher B Sherrill

11

1 reference

10 August 2017

Akin Akinc

12

1 reference

10 August 2017

Gregory Hinkle

13

1 reference

10 August 2017

Amy C Seila White

14

1 reference

10 August 2017

Bo Pang

15

1 reference

10 August 2017

Klaus Charisse

16

1 reference

10 August 2017

Rachel Meyers

17

1 reference

10 August 2017

Muthiah Manoharan

18

1 reference

10 August 2017

language of work or name

English

0 references

publication date

31 January 2012

1 reference

10 August 2017

1 reference

10 August 2017

18

1 reference

10 August 2017

3

1 reference

10 August 2017

557-568

1 reference

A status report on RNAi therapeutics

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Modulation of thermal stability can enhance the potency of siRNA

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Identification of small molecules that suppress microRNA function and reverse tumorigenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

The dicey role of Dicer: implications for RNAi therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Modified dsRNAs that are not processed by Dicer maintain potency and are incorporated into the RISC

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Distinct microRNA alterations characterize high- and low-grade bladder cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Drug delivery-mediated control of RNA immunostimulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Asymmetric shorter-duplex siRNA structures trigger efficient gene silencing with reduced nonspecific effects

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Dicer is regulated by cellular stresses and interferons

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Dicer, Drosha, and outcomes in patients with ovarian cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Potent RNAi by short RNA triggers.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Chemical modification patterns compatible with high potency dicer-substrate small interfering RNAs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Solid-phase synthesis of siRNA oligonucleotides.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

RNAi therapeutics: a potential new class of pharmaceutical drugs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Induction of the interferon response by siRNA is cell type- and duplex length-dependent

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Functional polarity is introduced by Dicer processing of short substrate RNAs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Does gastroenterology consultation change management of patients receiving hematopoietic stem cell transplantation?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Role for a bidentate ribonuclease in the initiation step of RNA interference

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

RNA interference is mediated by 21- and 22-nucleotide RNAs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Down-regulation of Dicer in hepatocellular carcinoma.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Rational design of cationic lipids for siRNA delivery

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Prognostic significance of Dicer expression in ovarian cancer-link to global microRNA changes and oestrogen receptor expression

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

RNAi-mediated gene silencing in non-human primates.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285942

The relationship between inflammatory bowel disease and socioeconomic variables

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22294662

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1261/RNA.031120.111

1 reference

10 August 2017

1 reference

10 August 2017

1 reference