Of flies and men; p53, a tumour suppressor (Q35785876)

10 August 2017

1 reference

title

Of flies and men; p53, a tumour suppressor (English)

1 reference

10 August 2017

Josephine E Sutcliffe

series ordinal

1

1 reference

PubMed ID

15165898

10 August 2017

Alexander Brehm

series ordinal

2

1 reference

PubMed ID

15165898

10 August 2017

language of work or name

English

0 references

publication date

1 June 2004

1 reference

10 August 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

FEBS Letters

1 reference

10 August 2017

567

1 reference

10 August 2017

1

1 reference

10 August 2017

86-91

1 reference

The genome sequence of Drosophila melanogaster

10 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Of flies and men--studying human disease in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

A survey of human disease gene counterparts in the Drosophila genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

p53 mutations in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Chk1 and Chk2 kinases in checkpoint control and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Functions of the MDM2 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

A novel cofactor for p300 that regulates the p53 response

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

ASPP proteins specifically stimulate the apoptotic function of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Post-translational modifications and activation of p53 by genotoxic stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Regulation of the specific DNA binding function of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

SUMO-1 modification activates the transcriptional response of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

DNA damage activates p53 through a phosphorylation-acetylation cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Recruitment of p300/CBP in p53-dependent signal pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Synergistic activation of transcription by CBP and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Binding and modulation of p53 by p300/CBP coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Deacetylation of p53 modulates its effect on cell growth and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Drosophila p53 binds a damage response element at the reaper locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Identification and characterization of a p53 homologue in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

In vivo p53 function is indispensable for DNA damage-induced apoptotic signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Drosophila p53 preserves genomic stability by regulating cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Dmp53 protects the Drosophila retina during a developmentally regulated DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Overexpression of mouse Mdm2 induces developmental phenotypes in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Drosophila Chk2 is required for DNA damage-mediated cell cycle arrest and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

c-Jun and p53 Activity Is Modulated by SUMO-1 Modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2004.03.122

10.1016/J.FEBSLET.2004.03.122

21 January 2018

Identifiers

DOI

1 reference

10 August 2017

1 reference

PubMed ID

15165898