Experimental autoimmune insulitis. Induction by T lymphocytes specific for a peptide of proinsulin. (Q35798318)

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20 October 2019

title

Experimental autoimmune insulitis. Induction by T lymphocytes specific for a peptide of proinsulin (English)

1 reference

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20 October 2019

author name string

A C Griffin

1

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20 October 2019

W Zhao

2

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20 October 2019

K W Wegmann

3

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20 October 2019

W F Hickley

4

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20 October 2019

language of work or name

English

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publication date

1 September 1995

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The American Journal of Pathology

20 October 2019

published in

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20 October 2019

volume

147

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20 October 2019

issue

3

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20 October 2019

page(s)

845-857

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Glutamic acid decarboxylase 67-reactive T cells: a marker of insulin-dependent diabetes

20 October 2019

cites work

1 reference

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Islet cell autoantigens in insulin-dependent diabetes

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Islet cell autoantigen 69 kD (ICA69). Molecular cloning and characterization of a novel diabetes-associated autoantigen

11 July 2018

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Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles

11 July 2018

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Potential autoantigens in IDDM. Expression of carboxypeptidase-H and insulin but not glutamate decarboxylase on the beta-cell surface

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

11 July 2018

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Presentation of beta-cell antigens to CD4+ and CD8+ T cells of non-obese diabetic mice

11 July 2018

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A genome-wide search for human type 1 diabetes susceptibility genes

11 July 2018

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Identification of myocarditogenic peptides derived from cardiac myosin capable of inducing experimental allergic myocarditis in the Lewis rat. The utility of a class II binding motif in selecting self-reactive peptides

11 July 2018

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Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta-cells in nonobese diabetic mice.

11 July 2018

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The T-cell repertoire contains cells reactive with hormones of the hypothalamic-pituitary-adrenal axis: recognition of synthetic peptide fragments of corticotropin-releasing hormone (CRH) and pro-opiomelanocortin (POMC) in the Lewis rat.

11 July 2018

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Dynamic time course studies of the spontaneously diabetic BB Wistar rat. III. Light-microscopic and ultrastructural observations of pancreatic islets of Langerhans

11 July 2018

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Spontaneous diabetes mellitus syndrome in the rat. I. Association with the major histocompatibility complex

11 July 2018

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Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor

11 July 2018

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Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes

11 July 2018

1 reference

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Increased proinsulin levels as an early indicator of B-cell dysfunction in non-diabetic twins of type 1 (insulin-dependent) diabetic patients.

11 July 2018

1 reference

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IDDM in BB rats. Enhanced MHC class I heavy-chain gene expression in pancreatic islets.

11 July 2018

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Immunotherapy of the nonobese diabetic mouse: treatment with an antibody to T-helper lymphocytes

11 July 2018

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Structural requirements for the interaction between peptide antigens and I-Ed molecules

11 July 2018

1 reference

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Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis

11 July 2018

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The pathogenesis of autoimmune diabetes mellitus

11 July 2018

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Immunologic and genetic studies of diabetes in the BB rat.

11 July 2018

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The insulin secretory granule

11 July 2018

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Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy.

11 July 2018

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Recognition of the HLA class II-peptide complex by T-cell receptor: reversal of major histocompatibility complex restriction of a T-cell clone by a point mutation in the peptide determinant

11 July 2018

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T cell determinants of myelin basic protein include a unique encephalitogenic I-E-restricted epitope for Lewis rats.

11 July 2018

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T-lymphocyte clone specific for pancreatic islet antigen

11 July 2018

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A sequence pattern common to T cell epitopes

11 July 2018

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Prediction of immunodominant helper T cell antigenic sites from the primary sequence

11 July 2018

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T-cell antigenic sites tend to be amphipathic structures

11 July 2018

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Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.

11 July 2018

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Characterization of a cDNA coding for rat glutamic acid decarboxylase

11 July 2018

1 reference

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Identification and cloning of a granule autoantigen (carboxypeptidase-H) associated with type I diabetes

11 July 2018

1 reference

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Cloning, characterization, and autoimmune recognition of rat islet glutamic acid decarboxylase in insulin-dependent diabetes mellitus

11 July 2018

1 reference

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Interactions between immunogenic peptides and MHC proteins

11 July 2018

1 reference

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Differential rates of conversion of rat proinsulins I and II. Evidence for slow cleavage at the B-chain/C-peptide junction of proinsulin II

11 July 2018

1 reference

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Overview: the major histocompatibility complex and insulin dependent diabetes mellitus

11 July 2018

1 reference

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Structural domains and molecular lifestyles of insulin and its precursors in the pancreatic beta cell

11 July 2018

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Insulitis in type 1 (insulin-dependent) diabetes mellitus in man--macrophages, lymphocytes, and interferon-gamma containing cells

11 July 2018

1 reference

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Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

11 July 2018

1 reference

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The Pathogenesis, Prediction, and Prevention of Insulin-Dependent Diabetes Mellitus

11 July 2018

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Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

11 July 2018

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The murine autoimmune diabetes model: NOD and related strains

11 July 2018

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Isolation and characterization of a cloned rat insulin gene

11 July 2018

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The R1-rat: a new RT1 haplotype

11 July 2018

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Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

11 July 2018

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Analysis of the roles of CD4+ and CD8+ T cells in autoimmune diabetes of NOD mice using transfer to NOD athymic nude mice.

25 September 2018

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Secretory granule autoantigen in insulin-dependent diabetes mellitus is related to 62 kDa heat-shock protein (hsp60)

25 September 2018

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Structural model of HLA-DR1 restricted T cell antigen recognition

25 September 2018

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12 December 2020

Macrophage infiltration precedes and is a prerequisite for lymphocytic insulitis in pancreatic islets of pre-diabetic BB rats

1 reference

12 December 2020

Revelation of specificity of 64K autoantibodies in IDDM serums by high-resolution 2-D gel electrophoresis. Unambiguous identification of 64K target antigen

1 reference

12 December 2020

Different lymphocyte subset distribution within "insulitis" islets of normoglycaemic and prediabetic BB/OK rats of similar age

1 reference

12 December 2020

64,000 Mr autoantibodies as predictors of insulin-dependent diabetes

1 reference

12 December 2020

A single dose of the MHC-linked susceptibility determinant associated with the RT1u haplotype is permissive for insulin-dependent diabetes mellitus in the BB rat

1 reference

12 December 2020

Genetic susceptibility to the development of spontaneous insulin-dependent diabetes mellitus in the rat

1 reference

12 December 2020

Prevention of autoimmune diabetes in the BB rat by intrathymic islet transplantation at birth

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12 December 2020

Involvement of dendritic cells in early insulitis of BB rats

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12 December 2020

CD8+ T-cells are required for adoptive transfer of the BB rat diabetic syndrome

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12 December 2020

Kinetics of proinsulin conversion in human islets

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12 December 2020

Following a diabetogenic T cell from genesis through pathogenesis

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12 December 2020

Identification of an N-terminally acetylated encephalitogenic epitope in myelin proteolipid apoprotein for the Lewis rat

1 reference

12 December 2020

Pancreas in recent onset insulin-dependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor V beta usage, and cytokine profile

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12 December 2020

Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome llq

1 reference

12 December 2020

The structure and evolution of the two nonallelic rat preproinsulin genes

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12 December 2020

HLA-D and -DR antigens in genetic analysis of insulin dependent diabetes mellitus

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12 December 2020

Spontaneous diabetes mellitus syndrome in the rat. II. T lymphopenia and its association with clinical disease and pancreatic lymphocytic infiltration

1 reference

12 December 2020

The genetic susceptibility to type 1 (insulin-dependent) diabetes: analysis of the HLA-DR association

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12 December 2020

The Onset and Progression of Pancreatic Insulitis in the Overt, Spontaneously Diabetic, Young Adult BB Rat Studied by Pancreatic Biopsy

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12 December 2020

T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis

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12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7545875%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

PubMed publication ID

7545875

1 reference