Inhibitory effects of antiarrhythmic drugs on phenacetin O-deethylation catalysed by human CYP1A2. (Q35803009)

10 August 2017

Inhibitory effects of antiarrhythmic drugs on phenacetin O-deethylation catalysed by human CYP1A2. (English)

1 reference

10 August 2017

K Kobayashi

1

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10 August 2017

M Nakajima

2

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10 August 2017

K Chiba

3

1 reference

10 August 2017

T Yamamoto

4

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10 August 2017

M Tani

5

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10 August 2017

T Ishizaki

6

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10 August 2017

Y Kuroiwa

7

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10 August 2017

language of work or name

English

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publication date

1 April 1998

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British Journal of Clinical Pharmacology

10 August 2017

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10 August 2017

45

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10 August 2017

4

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10 August 2017

361-368

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P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

The effects of selective serotonin reuptake inhibitors and their metabolites on S-mephenytoin 4'-hydroxylase activity in human liver microsomes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Metabolism of theophylline by cDNA-expressed human cytochromes P-450.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

A pharmacokinetic analysis program (multi) for microcomputer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Accumulation of caffeine in healthy volunteers treated with furafylline

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Oral mexiletine-theophylline interaction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Mexiletine metabolism in vitro by human liver.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Influence of debrisoquine phenotype and of quinidine on mexiletine disposition in man.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Mexiletine effects on theophylline disposition.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Toxic Interaction Between Fluvoxamine and Sustained Release Theophylline in an 11-Year-Old Boy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Theophylline toxicity after propafenone treatment: evidence for drug interaction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Theophylline-mexiletine interaction: a case report

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Characterization of human liver cytochromes P-450 involved in theophylline metabolism

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Relative potency of mexiletine, lidocaine, and tocainide as inhibitors of rat liver CYP1A1 activity.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873964

Cigarette smoking and theophyiiine clearance and metabolism

25 September 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.1998.T01-1-00692.X

Inhibition of theophylline metabolism by mexiletine in young male and female nonsmokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.1998.T01-1-00692.X

Influence of mexiletine on the pharmacokinetics of theophylline in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.1998.T01-1-00692.X

Effect of cigarette smoking on mexiletine kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.1998.T01-1-00692.X

Mexiletine and caffeine elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.1998.T01-1-00692.X

Fluvoxamine Inhibition and Carbamazepine Induction of the Metabolism of Clozapine

21 January 2018

1 reference

12 December 2020

A fluvoxamine-caffeine interaction study

1 reference

12 December 2020

Selective induction of propranolol metabolism by smoking: additional effects on renal clearance of metabolites

1 reference

12 December 2020

Mexiletine-theophylline interaction

1 reference

12 December 2020

1 reference

12 December 2020

Inhibitory studies of mexiletine and dextromethorphan oxidation in human liver microsomes

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12 December 2020

Possible theophylline-amiodarone interaction

1 reference

12 December 2020

Interaction between fluvoxamine and imipramine/desipramine in four patients

1 reference

12 December 2020

Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites

1 reference

12 December 2020

Propafenone-theophylline interaction

1 reference

12 December 2020

Fluvoxamine is a potent inhibitor of cytochrome P4501A2

1 reference

12 December 2020

Major pathway of imipramine metabolism is catalyzed by cytochromes P-450 1A2 and P-450 3A4 in human liver

1 reference

12 December 2020

Interaction of the enantiomers of fluoxetine and norfluoxetine with human liver cytochromes P450

1 reference

12 December 2020

Role of polymorphic debrisoquin 4-hydroxylase activity in the stereoselective disposition of mexiletine in humans

1 reference

12 December 2020

Development and preliminary application of a simple assay of S-mephenytoin 4-hydroxylase activity in human liver microsomes

1 reference

12 December 2020

10.1046/J.1365-2125.1998.T01-1-00692.X

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

1 reference