Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion (Q35809358)

10 August 2017

Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion (English)

1 reference

10 August 2017

1 reference

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26126854%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Lucas T Jae

3

1 reference

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14 June 2020

Margaret Kielian

8

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14 June 2020

John M Dye

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1 reference

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14 June 2020

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Kartik Chandran

1 reference

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14 June 2020

author name string

Lara M Kleinfelter

1

1 reference

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14 June 2020

Andrew S Herbert

4

1 reference

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14 June 2020

Eva Mittler

5

1 reference

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14 June 2020

Katie M Stiles

6

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14 June 2020

Ariel S Wirchnianski

7

1 reference

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14 June 2020

Thijn R Brummelkamp

9

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14 June 2020

publication date

30 June 2015

1 reference

10 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26126854%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

volume

6

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14 June 2020

issue

4

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14 June 2020

page(s)

e00801

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Mechanisms of Virus Membrane Fusion Proteins

14 June 2020

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1 reference

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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The major cellular sterol regulatory pathway is required for Andes virus infection

27 July 2018

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27 July 2018

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27 July 2018

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Old world arenaviruses enter the host cell via the multivesicular body and depend on the endosomal sorting complex required for transport

27 July 2018

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Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

27 July 2018

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Global gene disruption in human cells to assign genes to phenotypes by deep sequencing

27 July 2018

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Development of a lentiviral vector system to study the role of the Andes virus glycoproteins.

27 July 2018

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A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alter its protease dependence during cell entry

27 July 2018

1 reference

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A hantavirus causing hemorrhagic fever with renal syndrome requires gC1qR/p32 for efficient cell binding and infection

27 July 2018

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Mechanics of membrane fusion

27 July 2018

1 reference

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Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory element-binding protein processing and reduces lipogenic enzyme gene expression and lipid synthesis in cultured cells and experimental animals

27 July 2018

1 reference

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Hantavirus causing hemorrhagic fever with renal syndrome enters from the apical surface and requires decay-accelerating factor (DAF/CD55).

27 July 2018

1 reference

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Membrane lipids: where they are and how they behave

27 July 2018

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Crimean-Congo hemorrhagic fever virus glycoprotein processing by the endoprotease SKI-1/S1P is critical for virus infectivity

27 July 2018

1 reference

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Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking

27 July 2018

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CellProfiler: image analysis software for identifying and quantifying cell phenotypes

27 July 2018

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Cholesterol-dependent lipid assemblies regulate the activity of the ecto-nucleotidase CD39.

27 July 2018

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Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection

27 July 2018

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Interactions and trafficking of Andes and Sin Nombre Hantavirus glycoproteins G1 and G2.

27 July 2018

1 reference

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Cholesterol removal by methyl-beta-cyclodextrin inhibits poliovirus entry.

27 July 2018

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Recycling Compartments and the Internal Vesicles of Multivesicular Bodies Harbor Most of the Cholesterol Found in the Endocytic Pathway

27 July 2018

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Endoproteolytic processing of the lymphocytic choriomeningitis virus glycoprotein by the subtilase SKI-1/S1P.

27 July 2018

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Separation and characterization of late endosomal membrane domains

27 July 2018

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The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1/S1P.

27 July 2018

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A lethal disease model for hantavirus pulmonary syndrome

27 July 2018

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27 July 2018

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Biochemical consequences of a mutation that controls the cholesterol dependence of Semliki Forest virus fusion

27 July 2018

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A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

27 July 2018

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The cholesterol requirement for sindbis virus entry and exit and characterization of a spike protein region involved in cholesterol dependence

27 July 2018

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Spectrum of hantavirus infection: hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome

27 July 2018

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Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells

27 July 2018

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The role of low pH and disulfide shuffling in the entry and fusion of Semliki Forest virus and Sindbis virus

27 July 2018

1 reference

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beta3 Integrins mediate the cellular entry of hantaviruses that cause respiratory failure

27 July 2018

1 reference

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Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studies

27 July 2018

1 reference

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27 July 2018

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

27 July 2018

1 reference

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Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment

27 July 2018

1 reference

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Regulated cleavage of sterol regulatory element binding proteins requires sequences on both sides of the endoplasmic reticulum membrane

27 July 2018

1 reference

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Expression strategy of the M genome segment of Hantaan virus

27 July 2018

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27 July 2018

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27 July 2018

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Hantaan virus M RNA: coding strategy, nucleotide sequence, and gene order

27 July 2018

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Elastic deformation and failure of lipid bilayer membranes containing cholesterol

27 July 2018

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Coexpression of the membrane glycoproteins G1 and G2 of Hantaan virus is required for targeting to the Golgi complex

27 July 2018

1 reference

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Cholesterol is required for infection by Semliki Forest virus

27 July 2018

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Maturation of hantaan virus glycoproteins G1 and G2

27 July 2018

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Isolation of the Etiologic Agent of Korean Hemorrhagic Fever

27 July 2018

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Uncovering the mysteries of hantavirus infections

27 July 2018

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A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum

25 September 2018

1 reference

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Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entry

25 September 2018

1 reference

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Alphavirus Entry and Membrane Fusion

25 September 2018

1 reference

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Entry of bunyaviruses into mammalian cells

25 September 2018

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Haploid genetic screens in human cells identify host factors used by pathogens

25 September 2018

1 reference

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New and Old World hantaviruses differentially utilize host cytoskeletal components during their life cycles.

25 September 2018

1 reference

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Roles of endogenously synthesized sterols in the endocytic pathway.

25 September 2018

1 reference

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Hantavirus Gc glycoprotein: evidence for a class II fusion protein.

25 September 2018

1 reference

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Differential Requirements of Rab5 and Rab7 for Endocytosis of Influenza and Other Enveloped Viruses

25 September 2018

1 reference

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The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains.

25 September 2018

1 reference

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Hantaan virus enters cells by clathrin-dependent receptor-mediated endocytosis

25 September 2018

1 reference

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The Hantaan virus glycoprotein precursor is cleaved at the conserved pentapeptide WAASA.

25 September 2018

1 reference

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Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein.

25 September 2018

1 reference

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Cellular entry of hantaviruses which cause hemorrhagic fever with renal syndrome is mediated by beta3 integrins.

25 September 2018

1 reference

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Alteration of the myometrial plasma membrane cholesterol content with beta-cyclodextrin modulates the binding affinity of the oxytocin receptor

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26126854

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hantavirus pulmonary syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26126854

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Aminopyrrolidineamide inhibitors of site-1 protease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26126854

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MBIO.00801-15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26126854%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26126854%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26126854%20AND%20SRC:MED&resulttype=core&format=json