Peptide inhibitors of virus-cell fusion: enfuvirtide as a case study in clinical discovery and development (Q35818505)

10 August 2017

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title

Peptide inhibitors of virus-cell fusion: enfuvirtide as a case study in clinical discovery and development (English)

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10 August 2017

David A Cooper

1

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10 August 2017

Joep M A Lange

series ordinal

2

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10 August 2017

language of work or name

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1 July 2004

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Lancet Infectious Diseases

10 August 2017

published in

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10 August 2017

volume

4

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10 August 2017

issue

7

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10 August 2017

page(s)

426-436

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Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection

10 August 2017

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Safety and antiretroviral activity of chronic subcutaneous administration of T-20 in human immunodeficiency virus 1-infected children

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7 January 2021

The safety, plasma pharmacokinetics, and antiviral activity of subcutaneous enfuvirtide (T-20), a peptide inhibitor of gp41-mediated virus fusion, in HIV-infected adults.

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7 January 2021

A phase II clinical study of the long-term safety and antiviral activity of enfuvirtide-based antiretroviral therapy

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7 January 2021

Safety, tolerability, and plasma pharmacokinetics of high-strength formulations of enfuvirtide (T-20) in treatment-experienced HIV-1-infected patients

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7 January 2021

Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America

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7 January 2021

Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia

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7 January 2021

Pharmacokinetics of plasma enfuvirtide after subcutaneous administration to patients with human immunodeficiency virus: Inverse Gaussian density absorption and 2-compartment disposition

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7 January 2021

Influence of subcutaneous injection site on the steady-state pharmacokinetics of enfuvirtide (T-20) in HIV-1-infected patients

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7 January 2021

Population pharmacokinetics of enfuvirtide in pediatric patients with human immunodeficiency virus: searching for exposure-response relationships

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7 January 2021

Lack of enzyme-inducing effect of rifampicin on the pharmacokinetics of enfuvirtide

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7 January 2021

Injection site reactions with the HIV-1 fusion inhibitor enfuvirtide

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7 January 2021

The interstitial granulomatous drug reaction: a distinctive clinical and pathological entity

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7 January 2021

Interstitial granulomatous drug reaction with a histological pattern of interstitial granulomatous dermatitis

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7 January 2021

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7 January 2021

Clinical management of treatment-experienced, HIV-infected patients with the fusion inhibitor enfuvirtide: consensus recommendations

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7 January 2021

Effect of highly active antiretroviral therapy on the incidence of bacterial pneumonia in HIV-infected subjects

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7 January 2021

HIV-associated bacterial pneumonia in the era of highly active antiretroviral therapy

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7 January 2021

Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides.

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7 January 2021

Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

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7 January 2021

Uncommon mutations at residue positions critical for enfuvirtide (T-20) resistance in enfuvirtide-naive patients infected with subtype B and non-B HIV-1 strains

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7 January 2021

Minimal variation in T-20 binding domain of different HIV-1 subtypes from antiretroviral-naive and -experienced patients

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7 January 2021

Primary genotypic resistance of HIV-1 to the fusion inhibitor T-20 in long-term infected patients

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7 January 2021

HIV-1 resistance to the gp41-dependent fusion inhibitor C-34.

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7 January 2021

Short-term safety and antiretroviral activity of T-1249, a second-generation fusion inhibitor of HIV.

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7 January 2021

Impaired 2',3'-dideoxy-3'-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 with a possible role for ATP-binding cassette C11

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7 January 2021

MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs

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7 January 2021

P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?

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7 January 2021

P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals

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7 January 2021

Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2).

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7 January 2021

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5

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7 January 2021

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

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https://api.crossref.org/works/10.1016%2FS1473-3099%2804%2901058-8

7 January 2021

Peptides corresponding to the heptad repeat motifs in the transmembrane protein (gp41) of human immunodeficiency virus type 1 elicit antibodies to receptor-activated conformations of the envelope glycoprotein

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https://api.crossref.org/works/10.1016%2FS1473-3099%2804%2901058-8

7 January 2021

The biology of interferon-alpha and the clinical significance of anti-interferon antibodies

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7 January 2021

Enfuvirtide (T-20) cross-reactive glycoprotein 41 antibody does not impair the efficacy or safety of enfuvirtide

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7 January 2021

Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex

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7 January 2021

Long-term treatment with subcutaneous T-20, a fusion inhibitor, in HIV-infected patients: patient satisfaction and impact on activities of daily living

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7 January 2021

Subcutaneous injection survey: psychometric evaluation of a treatment satisfaction instrument associated with a novel HIV medication

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7 January 2021

Patient Acceptance of Self-Injected Enfuvirtide at 8 and 24 Weeks

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7 January 2021

Mode of action of an antiviral peptide from HIV-1. Inhibition at a post-lipid mixing stage

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7 January 2021

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Identifiers

DOI

1 reference

10 August 2017

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