Heart mitochondria signaling pathways: appraisal of an emerging field (Q35819361)

10 August 2017

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title

Heart mitochondria signaling pathways: appraisal of an emerging field (English)

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10 August 2017

José Marín-García

1

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10 August 2017

Michael J Goldenthal

series ordinal

2

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10 August 2017

publication date

23 June 2004

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Journal of Molecular Medicine

10 August 2017

published in

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10 August 2017

volume

82

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10 August 2017

issue

9

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10 August 2017

page(s)

565-578

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Hypoxemia is associated with mitochondrial DNA damage and gene induction. Implications for cardiac disease

10 August 2017

cites work

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12 December 2020

Serotonin is a novel survival factor of cardiomyocytes: mitochondria as a target of 5-HT2B receptor signaling

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12 December 2020

The role of the peroxisome proliferator-activated receptor alpha (PPAR alpha) in the control of cardiac lipid metabolism

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12 December 2020

Developing a strategy to define the effects of insulin-like growth factor-1 on gene expression profile in cardiomyocytes

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12 December 2020

Hypoxia inhibits the peroxisome proliferator-activated receptor alpha/retinoid X receptor gene regulatory pathway in cardiac myocytes: a mechanism for O2-dependent modulation of mitochondrial fatty acid oxidation

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12 December 2020

Alterations in apoptosis regulatory factors during hypertrophy and heart failure

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12 December 2020

Stimulation of mitochondrial gene expression and proliferation of mitochondria following impairment of cellular energy transfer by inhibition of the phosphocreatine circuit in rat hearts

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12 December 2020

Deficit of in vivo mitochondrial ATP production in patients with Friedreich ataxia

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12 December 2020

Mitochondrial pathology in cardiac failure

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12 December 2020

Developmental changes in energy substrate use by the heart

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12 December 2020

Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death

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12 December 2020

Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection

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12 December 2020

Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide

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12 December 2020

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

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12 December 2020

Amino acid deprivation induces translation of branched-chain alpha-ketoacid dehydrogenase kinase

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12 December 2020

Molecular and cellular mechanisms of myocardial failure

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12 December 2020

Hypoxic induction of hypoxia-inducible factor-1alpha and oxygen-regulated gene expression in mitochondrial DNA-depleted HeLa cells.

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12 December 2020

Nitric oxide synthase in porcine heart mitochondria: evidence for low physiological activity

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12 December 2020

Protein kinase Cepsilon interacts with and inhibits the permeability transition pore in cardiac mitochondria

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12 December 2020

A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator

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12 December 2020

Control of mitochondrial membrane potential and ROS formation by reversible phosphorylation of cytochrome c oxidase

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12 December 2020

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

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12 December 2020

Characterization of proteins phosphorylated by the cAMP-dependent protein kinase of bovine heart mitochondria

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12 December 2020

Cytokine-Stimulated Nitric Oxide Production Inhibits Mitochondrial Activity in Cardiac Myocytes

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12 December 2020

Myocardial free fatty acid and glucose use after carvedilol treatment in patients with congestive heart failure

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12 December 2020

Adaptive changes in response to acute hypoxia, ischemia and reperfusion in human cardiac cell.

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12 December 2020

Biochemical and molecular basis for mitochondrial cardiomyopathy in neonates and children

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12 December 2020

cAMP-dependent protein phosphorylation in mitochondria of bovine heart

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12 December 2020

Dual gene therapy with SERCA1 and Kir2.1 abbreviates excitation without suppressing contractility

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12 December 2020

Cardiac mitochondrial complex activity is enhanced by heat shock proteins.

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12 December 2020

Alterations in mitochondrial function in a mouse model of hypertrophic cardiomyopathy

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12 December 2020

Coordinate regulation of metabolic enzyme encoding genes during cardiac development and following carvedilol therapy in spontaneously hypertensive rats

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12 December 2020

Evidence of undiscovered cell regulatory mechanisms: phosphoproteins and protein kinases in mitochondria.

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12 December 2020

The rapid mode of calcium uptake into heart mitochondria (RaM): comparison to RaM in liver mitochondria

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12 December 2020

Chronic hypoxia modulates the interleukin-1beta-stimulated inducible nitric oxide synthase pathway in cardiac myocytes

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12 December 2020

Evidence for the presence of a reversible Ca2+-dependent pore activated by oxidative stress in heart mitochondria

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12 December 2020

Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive K+ channels. Possible mechanism of cardioprotection.

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12 December 2020

Ischemic preconditioning: from adenosine receptor to KATP channel

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12 December 2020

The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes

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12 December 2020

Nuclear genes in mitochondrial disorders.

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12 December 2020

Glucocorticoid and thyroid hormone receptors in mitochondria of animal cells

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12 December 2020

Phosphorylation of mitochondrial elongation factor Tu in ischemic myocardium: basis for chloramphenicol-mediated cardioprotection

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12 December 2020

Induction of UCP2 mRNA by thyroid hormones in rat heart

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12 December 2020

A variant form of the nuclear triiodothyronine receptor c-ErbAalpha1 plays a direct role in regulation of mitochondrial RNA synthesis

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12 December 2020

Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake

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12 December 2020

Regulation of mitochondrial metabolism through changes in matrix volume

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12 December 2020

Biochemical and morphological study of cardiac hypertrophy. Effects of thyroxine on enzyme activities in the rat myocardium

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12 December 2020

Mutant NDUFS3 subunit of mitochondrial complex I causes Leigh syndrome

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12 December 2020

Mitochondrial proliferation in cardiac hypertrophy

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12 December 2020

Antiapoptotic effect of nicorandil mediated by mitochondrial atp-sensitive potassium channels in cultured cardiac myocytes

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12 December 2020

Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits

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12 December 2020

Nuclear activators and coactivators in mammalian mitochondrial biogenesis

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12 December 2020

Transcriptional effects of chronic Akt activation in the heart.

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12 December 2020

Mitochondria play a critical role in cardioprotection

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12 December 2020

Oxidative phosphorylation diseases and mitochondrial DNA mutations: diagnosis and treatment

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12 December 2020

TNF-alpha and IL-1 alpha inhibit both pyruvate dehydrogenase activity and mitochondrial function in cardiomyocytes: evidence for primary impairment of mitochondrial function

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12 December 2020

Adult cardiac stem cells are multipotent and support myocardial regeneration

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12 December 2020

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

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12 December 2020

Propagation of the apoptotic signal by mitochondrial waves

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12 December 2020

NFATc3 and NFATc4 Are Required for Cardiac Development and Mitochondrial Function

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12 December 2020

Myocardial K(ATP) channels in preconditioning

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12 December 2020

Control of mitochondrial ATP synthase in rat cardiomyocytes: effects of thyroid hormone

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12 December 2020

Importance of PKC and tyrosine kinase in single or multiple cycles of preconditioning in rat hearts

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12 December 2020

Nitric oxide inhibits mitochondrial NADH:ubiquinone reductase activity through peroxynitrite formation

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12 December 2020

Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles.

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12 December 2020

Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo

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12 December 2020

Use of ruthenium red as an inhibitor of mitochondrial Ca(2+) uptake in single rat cardiomyocytes

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12 December 2020

Analysis of steady-state protein phosphorylation in mitochondria using a novel fluorescent phosphosensor dye.

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12 December 2020

Signal transduction of ischemic preconditioning

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12 December 2020

Activation of the JNK pathway is important for cardiomyocyte death in response to simulated ischemia

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12 December 2020

Hypothermia preserves function and signaling for mitochondrial biogenesis during subsequent ischemia

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12 December 2020

Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis

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12 December 2020

Calcium signal transmission between ryanodine receptors and mitochondria in cardiac muscle

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12 December 2020

Understanding the impact of mitochondrial defects in cardiovascular disease: a review

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12 December 2020

Reversible ischemic inhibition of F(1)F(0)-ATPase in rat and human myocardium

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12 December 2020

Calcineurin transgenic mice have mitochondrial dysfunction and elevated superoxide production

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12 December 2020

Role of calcium ions in regulation of mammalian intramitochondrial metabolism

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12 December 2020

Regulation of mitochondrial metabolism by ER Ca2+ release: an intimate connection

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12 December 2020

Cellular oxygen sensing by mitochondria: old questions, new insight

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12 December 2020

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

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12 December 2020

Activation of mitochondrial ATP-sensitive K(+) channel for cardiac protection against ischemic injury is dependent on protein kinase C activity.

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12 December 2020

Ca(2+) activation of heart mitochondrial oxidative phosphorylation: role of the F(0)/F(1)-ATPase

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12 December 2020

Electrical stimulation of neonatal cardiomyocytes results in the sequential activation of nuclear genes governing mitochondrial proliferation and differentiation

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12 December 2020

Maladaptive growth in the failing heart: the cardiomyopathy of overload

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12 December 2020

Dual signaling via protein kinase C and phosphatidylinositol 3'-kinase/Akt contributes to bradykinin B2 receptor-induced cardioprotection in guinea pig hearts

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12 December 2020

Matrix volume measurements challenge the existence of diazoxide/glibencamide-sensitive KATP channels in rat mitochondria

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12 December 2020

Effect of idebenone on cardiomyopathy in Friedreich's ataxia: a preliminary study

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12 December 2020

Lipid peroxidation and alterations to oxidative metabolism in mitochondria isolated from rat heart subjected to ischemia and reperfusion

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12 December 2020

Peroxisome proliferator-activated receptor (PPAR) alpha and PPARbeta/delta, but not PPARgamma, modulate the expression of genes involved in cardiac lipid metabolism

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12 December 2020

ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases

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12 December 2020

Effect of thyroid hormone on mtHsp70 expression, mitochondrial import and processing in cardiac muscle

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12 December 2020

Intravenous nicorandil can preserve microvascular integrity and myocardial viability in patients with reperfused anterior wall myocardial infarction

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12 December 2020

Regulation and co-ordination of nuclear gene expression during mitochondrial biogenesis

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12 December 2020

Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy

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12 December 2020

Uptake of calcium by mitochondria: transport and possible function

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12 December 2020

Fatal infantile cardioencephalomyopathy with COX deficiency and mutations in SCO2, a COX assembly gene

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12 December 2020

Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis

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12 December 2020

Signaling pathways for cardiac hypertrophy and failure

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12 December 2020

Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria

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12 December 2020

Antiarrhythmic Drug Target Choices and Screening

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12 December 2020

Reperfusion injury induces apoptosis in rabbit cardiomyocytes

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12 December 2020

Integrating cytosolic calcium signals into mitochondrial metabolic responses

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12 December 2020

Fatty acid-induced apoptosis in neonatal cardiomyocytes: redox signaling

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12 December 2020

Mitochondrial PKCepsilon and MAPK form signaling modules in the murine heart: enhanced mitochondrial PKCepsilon-MAPK interactions and differential MAPK activation in PKCepsilon-induced cardioprotection

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12 December 2020

Long-term regulation of pyruvate dehydrogenase kinase by high-fat feeding. Experiments in vivo and in cultured cardiomyocytes

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12 December 2020

An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics

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12 December 2020

Disorders of mitochondrial long-chain fatty acid oxidation

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12 December 2020

Missense mutations in the beta-myosin heavy-chain gene cause central core disease in hypertrophic cardiomyopathy

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12 December 2020

Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses

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12 December 2020

The energy substrate switch during development of heart failure: gene regulatory mechanisms (Review)

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12 December 2020

Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression.

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12 December 2020

Mitochondrial ROS initiate phosphorylation of p38 MAP kinase during hypoxia in cardiomyocytes

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12 December 2020

Regulation of mitochondrial biogenesis in skeletal muscle by CaMK

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12 December 2020

Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes.

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12 December 2020

Myocyte death, growth, and regeneration in cardiac hypertrophy and failure

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12 December 2020

Functional consequences of thyroid hormone-induced changes in the mitochondrial protein import pathway

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12 December 2020

Arrhythmias and conduction defects as presenting symptoms of fatty acid oxidation disorders in children

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12 December 2020

Nitric oxide regulates oxygen uptake and hydrogen peroxide release by the isolated beating rat heart

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12 December 2020

PUFA and aging modulate cardiac mitochondrial membrane lipid composition and Ca2+ activation of PDH

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12 December 2020

Old players in a new role: mitochondria-associated membranes, VDAC, and ryanodine receptors as contributors to calcium signal propagation from endoplasmic reticulum to the mitochondria

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12 December 2020

PPAR signaling in the control of cardiac energy metabolism

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12 December 2020

Increased uncoupling proteins and decreased efficiency in palmitate-perfused hyperthyroid rat heart

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12 December 2020

Mitochondrial toxicity of antiviral drugs

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12 December 2020

Akt/protein kinase B promotes organ growth in transgenic mice

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12 December 2020

Uncoupling protein 3 transcription is regulated by peroxisome proliferator-activated receptor (alpha) in the adult rodent heart

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12 December 2020

Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC.

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12 December 2020

The NDUFS4 nuclear gene of complex I of mitochondria and the cAMP cascade

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12 December 2020

Mitochondria-assisted cell suicide: a license to kill

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12 December 2020

Gene regulatory mechanisms governing energy metabolism during cardiac hypertrophic growth

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12 December 2020

10.1007/S00109-004-0567-7

Identifiers

DOI

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10 August 2017

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