Degradable polyethylenimine derivate coupled to a bifunctional peptide R13 as a new gene-delivery vector (Q35821070)

10 August 2017

Degradable polyethylenimine derivate coupled to a bifunctional peptide R13 as a new gene-delivery vector (English)

1 reference

10 August 2017

Kehai Liu

1

1 reference

10 August 2017

Xiaoyu Wang

2

1 reference

10 August 2017

Wei Fan

3

1 reference

10 August 2017

Qing Zhu

4

1 reference

10 August 2017

Jingya Yang

5

1 reference

10 August 2017

Jing Gao

6

1 reference

10 August 2017

Shen Gao

7

1 reference

10 August 2017

language of work or name

English

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publication date

29 February 2012

1 reference

International Journal of Nanomedicine

10 August 2017

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10 August 2017

7

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10 August 2017

1149-1162

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Second-generation aptamer-conjugated PSMA-targeted delivery system for prostate cancer therapy

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Enhanced gene delivery using biodegradable poly(ester amine)s (PEAs) based on low-molecular-weight polyethylenimine and poly(epsilon-caprolactone)-pluronic-poly(epsilon-caprolactone).

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Low molecular weight polyethylenimine cross-linked by 2-hydroxypropyl-gamma-cyclodextrin coupled to peptide targeting HER2 as a gene delivery vector.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Pluronic/polyethylenimine shell crosslinked nanocapsules with embedded magnetite nanocrystals for magnetically triggered delivery of siRNA.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

PAMAM-triamcinolone acetonide conjugate as a nucleus-targeting gene carrier for enhanced transfer activity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Enhanced transfection of polyplexes based on pluronic-polypropylenimine dendrimer for gene transfer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Revisit the complexation of PEI and DNA - how to make low cytotoxic and highly efficient PEI gene transfection non-viral vectors with a controllable chain length and structure?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Synthesis of a novel biodegradable poly(ester amine) (PEAs) copolymer based on low-molecular-weight polyethyleneimine for gene delivery

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Self-assembling micelle-like nanoparticles based on phospholipid-polyethyleneimine conjugates for systemic gene delivery

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Different internalization pathways of polymeric micelles and unimers and their effects on vesicular transport

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Progress in developing cationic vectors for non-viral systemic gene therapy against cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

A degradable hyperbranched poly(ester amine) based on poloxamer diacrylate and polyethylenimine as a gene carrier

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Synthesis and characterization of a novel arginine-grafted dendritic block copolymer for gene delivery and study of its cellular uptake pathway leading to transfection

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

A biodegradable poly(ester amine) based on polycaprolactone and polyethylenimine as a gene carrier

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Polyethylenimine-based non-viral gene delivery systems

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Degradable polyethylenimine-alt-poly(ethylene glycol) copolymers as novel gene carriers

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Evaluation of transportan 10 in PEI mediated plasmid delivery assay

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters).

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Tat peptide-mediated cellular delivery: back to basics

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Polymer genomics: shifting the gene and drug delivery paradigms.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Pluronic block copolymers: novel functional molecules for gene therapy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Changing face of microglia

11 July 2018

1 reference

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

21 January 2018

1 reference

Microglial physiology: unique stimuli, specialized responses

21 January 2018

1 reference

The myeloid cells of the central nervous system parenchyma

21 January 2018

1 reference

Does neuroinflammation fan the flame in neurodegenerative diseases?

21 January 2018

1 reference

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

21 January 2018

1 reference

Microglial activation and chronic neurodegeneration

21 January 2018

1 reference

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

21 January 2018

1 reference

Nitric oxide and neuronal death

21 January 2018

1 reference

Inflammatory neurodegeneration and mechanisms of microglial killing of neurons

21 January 2018

1 reference

Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

Active immunization with amyloid-beta 1-42 impairs memory performance through TLR2/4-dependent activation of the innate immune system.

21 January 2018

1 reference

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

21 January 2018

1 reference

Celastrol: Molecular targets of Thunder God Vine

21 January 2018

1 reference

Celastrol induces apoptosis in non-small-cell lung cancer A549 cells through activation of mitochondria- and Fas/FasL-mediated pathways

21 January 2018

1 reference

Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice

21 January 2018

1 reference

Induction of heat shock proteins in differentiated human and rodent neurons by celastrol

21 January 2018

1 reference

Up-regulation of death receptor 4 and 5 by celastrol enhances the anti-cancer activity of TRAIL/Apo-2L.

21 January 2018

1 reference

Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors

21 January 2018

1 reference

Celastrol inhibits Hsp90 chaperoning of steroid receptors by inducing fibrillization of the Co-chaperone p23

21 January 2018

1 reference

Characterization of celastrol to inhibit hsp90 and cdc37 interaction

21 January 2018

1 reference

Celastrol inhibits production of nitric oxide and proinflammatory cytokines through MAPK signal transduction and NF-kappaB in LPS-stimulated BV-2 microglial cells

21 January 2018

1 reference

A cellular viability assay to monitor drug toxicity

21 January 2018

1 reference

Activation of the heat shock response in a primary cellular model of motoneuron neurodegeneration-evidence for neuroprotective and neurotoxic effects

21 January 2018

1 reference

Self-assembled nanoplatform for targeted delivery of chemotherapy agents via affinity-regulated molecular interactions

21 January 2018

1 reference

Tunable physiologic interactions of adhesion molecules for inflamed cell-selective drug delivery

21 January 2018

1 reference

Nanosystems for simultaneous imaging and drug delivery to T cells

21 January 2018

1 reference

Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications

21 January 2018

1 reference

Dendimer-mediated solubilization, formulation development and in vitro-in vivo assessment of piroxicam.

21 January 2018

1 reference

Dendrimers as versatile platform in drug delivery applications

21 January 2018

1 reference

Dendrimers for enhanced drug solubilization.

21 January 2018

1 reference

Dendrimers in biomedical applications--reflections on the field

21 January 2018

1 reference

A New Class of Polymers: Starburst-Dendritic Macromolecules

21 January 2018

1 reference

Surface modified poly(amido)amine dendrimers as diverse nanomolecules for biomedical applications

21 January 2018

1 reference

Dendrimer-mediated transdermal delivery: enhanced bioavailability of indomethacin

21 January 2018

1 reference

Dendrimers as potential drug carriers. Part I. Solubilization of non-steroidal anti-inflammatory drugs in the presence of polyamidoamine dendrimers

21 January 2018

1 reference

Intrinsic targeting of inflammatory cells in the brain by polyamidoamine dendrimers upon subarachnoid administration

21 January 2018

1 reference

Monokine production by microglial cell clones

21 January 2018

1 reference

Quantitative imaging assay for NF-kappaB nuclear translocation in primary human macrophages.

21 January 2018

1 reference

Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease

21 January 2018

1 reference

Celastrol suppresses morphological and transcriptional responses in microglial cells upon stimulation with double-stranded RNA.

21 January 2018

1 reference

HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way

21 January 2018

1 reference

Release of prostaglandin E(2) and nitric oxide from spinal microglia is dependent on activation of p38 mitogen-activated protein kinase

21 January 2018

1 reference

Celastrol acts as a potent antimetastatic agent targeting beta1 integrin and inhibiting cell-extracellular matrix adhesion, in part via the p38 mitogen-activated protein kinase pathway

21 January 2018

1 reference

Host-guest chemistry and physicochemical properties of the dendrimer-mycophenolic acid complex

21 January 2018

1 reference

The effect of PAMAM dendrimer generation size and surface functional group on the aqueous solubility of nifedipine

21 January 2018

1 reference

MAPK signal transduction underlying brain inflammation and gliosis as therapeutic target

21 January 2018

1 reference

Celastrol induces expression of heme oxygenase-1 through ROS/Nrf2/ARE signaling in the HaCaT cells

21 January 2018

1 reference

Suppression of inflammatory responses by celastrol, a quinone methide triterpenoid isolated from Celastrus regelii

21 January 2018

1 reference

Tripterine prevents endothelial barrier dysfunction by inhibiting endogenous peroxynitrite formation

21 January 2018

1 reference

Gene-specific repression of proinflammatory cytokines in stimulated human macrophages by nuclear IκBα.

21 January 2018

1 reference

Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer.

21 January 2018

1 reference

Charge-reversal polyamidoamine dendrimer for cascade nuclear drug delivery.

21 January 2018

1 reference

Mechanistic studies of in vitro cytotoxicity of poly(amidoamine) dendrimers in mammalian cells

21 January 2018

1 reference

Mycoplasma hyopneumoniae induces pro-inflammatory cytokine and nitric oxide production through NFκB and MAPK pathways in RAW264.7 cells.

21 January 2018

1 reference

Anti-inflammatory and anti-oxidant activity of anionic dendrimer-N-acetyl cysteine conjugates in activated microglial cells

21 January 2018

1 reference

Cutting edge: critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cells

21 January 2018

1 reference

p38(MAPK): stress responses from molecular mechanisms to therapeutics

21 January 2018

1 reference

Resveratrol differentially modulates inflammatory responses of microglia and astrocytes

21 January 2018

1 reference

Gene delivery targeted to the brain using an Angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer.

21 January 2018

1 reference

Cancer-specific transgene expression mediated by systemic injection of nanoparticles

21 January 2018

1 reference

Dendrimers as therapeutic agents: a systematic review.

21 January 2018

1 reference

Phase 1 randomized trial of the vaginal safety and acceptability of SPL7013 gel (VivaGel) in sexually active young women (MTN-004)

21 January 2018

1 reference

Safety, tolerability, and pharmacokinetics of SPL7013 gel (VivaGel): a dose ranging, phase I study.

21 January 2018

1 reference

Preparation and evaluation of 99mTc-labeled cyclic arginine-glycine-aspartate (RGD) peptide for integrin targeting

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Design, preparation, in vitro and in vivo evaluation of (99m)Tc-N2S2-Tat(49-57)-bombesin: a target-specific hybrid radiopharmaceutical.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Bioreducible poly(amido amine)s with oligoamine side chains: synthesis, characterization, and structural effects on gene delivery

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Direct electrophilic radiofluorination of a cyclic RGD peptide for in vivo alpha(v)beta3 integrin related tumor imaging.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Molecular Mechanism of Inhibition of the Human Protein Complex Hsp90-Cdc37, a Kinome Chaperone-Cochaperone, by Triterpene Celastrol

24 September 2018

1 reference

Synthesis of poly(acrylic acid) (PAA) modified Pluronic P123 copolymers for pH-stimulated release of Doxorubicin

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299202

Inhibition of NF-κB activation through targeting IκB kinase by celastrol, a quinone methide triterpenoid

22 October 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/NNM.12.16

1 reference

10 August 2017

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10 August 2017

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