Adiposity signals, genetic and body weight regulation in humans (Q35821145)

10 August 2017

1 reference

title

Adiposity signals, genetic and body weight regulation in humans (English)

1 reference

10 August 2017

4

Clément K

1 reference

10 August 2017

Cancello R

1

1 reference

10 August 2017

Tounian A

series ordinal

2

1 reference

10 August 2017

Poitou Ch

series ordinal

3

1 reference

10 August 2017

publication date

1 June 2004

1 reference

10 August 2017

published in

Diabetes and Metabolism

1 reference

10 August 2017

volume

30

1 reference

10 August 2017

issue

3

1 reference

10 August 2017

page(s)

215-227

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

10 August 2017

1 reference

7 January 2021

Changes in Energy Expenditure Resulting from Altered Body Weight

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Genetics and pathophysiology of human obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Body Weight Set-Points: Determination and Adjustment

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Positional cloning of the mouse obese gene and its human homologue

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Central nervous system control of food intake

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Brain pathways controlling food intake and body weight.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Is the energy homeostasis system inherently biased toward weight gain?

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Effect of Fasting, Refeeding, and Dietary Fat Restriction on Plasma Leptin Levels

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Response of leptin to short-term and prolonged overfeeding in humans

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Leptin: the tale of an obesity gene

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The therapeutic potential of leptin

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Identification of SOCS-3 as a potential mediator of central leptin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Recombinant variant of ciliary neurotrophic factor for weight loss in obese adults: a randomized, dose-ranging study

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Insulin action and secretion in healthy, glucose tolerant first degree relatives of patients with type 2 diabetes mellitus. Influence of body weight

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Regulation of food intake and body weight by insulin

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

CNS melanocortin system involvement in the regulation of food intake.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Role of brain insulin receptor in control of body weight and reproduction

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Effects of meal ingestion on plasma amylin concentration in NIDDM and nondiabetic humans

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Amylin: history and overview

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Effects of glucagon, insulin, amylin and CGRP on feeding

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Amylin: a novel action in the brain to reduce body weight

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Differential permeability of the blood-brain barrier to two pancreatic peptides: insulin and amylin

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Permeability of the blood-brain barrier to amylin

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Amylin, food intake, and obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Cytokines and feeding

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Muscle-derived interleukin-6: possible biological effects

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Cellular localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Adipose tissue as an endocrine and paracrine organ

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Effects of repeated stress on expression of interleukin-6 (IL-6) and IL-6 receptor mRNAs in rat hypothalamus and midbrain

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Expression of immunoregulatory cytokines in neurons of the lateral hypothalamic area and amygdaloid nuclear complex of rats immunized against human IgG

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Interleukin-6-deficient mice develop mature-onset obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Intracerebroventricular interleukin-6 treatment decreases body fat in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Interleukin-6 causes hypocholesterolemia in middle-aged and old rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Dose Effects of Recombinant Human lnterleukin-6 on Pituitary Hormone Secretion and Energy Expenditure

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Interleukin-6 production in human subcutaneous abdominal adipose tissue: the effect of exercise

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Metabolic effects of interleukin-6 in human splanchnic and adipose tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

beta-Adrenergic regulation of IL-6 release from adipose tissue: in vivo and in vitro studies

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Elevated Levels of Interleukin 6 Are Reduced in Serum and Subcutaneous Adipose Tissue of Obese Women after Weight Loss

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Interactions of cytokines with the blood-brain barrier: implications for feeding

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Plasma interleukin-18 concentrations are elevated in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Plasma interleukin-8 concentrations are increased in obese subjects and related to fat mass and tumor necrosis factor-alpha system

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Plasma interleukin 8 concentrations in obese subjects with impaired glucose tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Adiponectin and Metabolic Syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The role of the novel adipocyte-derived hormone adiponectin in human disease

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Update on adipocyte hormones: regulation of energy balance and carbohydrate/lipid metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Genetics and the pathophysiology of obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Effects of recombinant leptin therapy in a child with congenital leptin deficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

1 reference

7 January 2021

Quantitative-trait loci influencing body-mass index reside on chromosomes 7 and 13: the National Heart, Lung, and Blood Institute Family Heart Study

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

A polymorphism in the 5' untranslated region of the human ob gene is associated with low leptin levels

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Association of the G-2548A polymorphism in the 5′ region of the LEP gene with overweight

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Partial leptin deficiency and human adiposity.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Linkage and association of the CA repeat polymorphism of the IL6 gene, obesity-related phenotypes, and bone mineral density (BMD) in two independent Caucasian populations

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The interleukin 6-174G/C polymorphism is associated with indices of obesity in men.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Promoter polymorphisms of the TNF-alpha (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The effect of the -308A allele of the TNF-alpha gene on insulin action is dependent on obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Excessive fat accumulation is associated with the TNFα -308 G/A promoter polymorphism in women but not in men

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Tumour necrosis factor-alpha (TNF-alpha) polymorphisms-857C/A and -863C/A are associated with TNF-alpha secretion from human adipose tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

A common functional polymorphism (C-->A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-alpha) gene associated with reduced circulating levels of TNF-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

A polymorphic marker in the leptin gene associated with Japanese morbid obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Novel polymorphism of the human ob gene promoter in lean and morbidly obese subjects

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Genetic variation in the leptin receptor gene, leptin, and weight gain in young Dutch adults

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The Gln223Arg and Lys656Asn polymorphisms in the human leptin receptor do not associate with traits related to obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Leptin receptor gene variation and obesity: lack of association in a white British male population

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Genetic studies of the leptin receptor gene in morbidly obese French Caucasian families

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Linkages and associations between the leptin receptor (LEPR) gene and human body composition in the Québec Family Study

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The Gln223Arg polymorphism of the leptin receptor in Pima Indians: influence on energy expenditure, physical activity and lipid metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Leptin receptor Gln223Arg variant is associated with a cluster of metabolic abnormalities in response to long-term overfeeding

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The Q223R polymorphism of the leptin receptor gene is significantly associated with obesity and predicts a small percentage of body weight and body composition variability

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Polymorphisms in the leptin receptor gene, body composition and fat distribution in overweight and obese women

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

LEPR gene polymorphisms: associations with overweight, fat mass and response to diet in women

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Combination of polymorphisms in OB-R and the OB gene associated with insulin resistance in Nauruan males

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Genetic Variation and Obesity in Australian Women: A Prospective Study

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Association analysis of genes involved in the leptin-signaling pathway with obesity in Brazil

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The C-174G promoter polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Interleukin-6 gene polymorphism and insulin sensitivity.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The interleukin-6 (-174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Tumor necrosis factor-alpha--308 G/A polymorphism in obese Caucasians

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Polymorphisms of the tumour necrosis factor-alpha gene, coronary heart disease and obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The TNF-alpha gene NcoI polymorphism at position -308 of the promoter influences insulin resistance, and increases serum triglycerides after postprandial lipaemia in familiar obesity.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Association of the TNF-alpha -308 G/A promoter polymorphism with insulin resistance in obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Gene polymorphisms in tumor necrosis factor locus and waist-hip ratio in obese Koreans

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The TNF-beta gene Nco I polymorphism is not associated with hypertriglyceridemia or insulin resistance in lean and obese subjects

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Tumor necrosis factor alpha gene G-308A polymorphism, insulin resistance, and fasting plasma glucose in young, older, and diabetic Japanese men.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Tumor necrosis factor alpha gene G-308A polymorphism in the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The G-308A variant of the Tumor Necrosis Factor-alpha (TNF-alpha) gene is not associated with obesity, insulin resistance and body fat distribution

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Increased abdominal obesity, insulin and glucose levels in nondiabetic subjects with a T29C polymorphism of the transforming growth factor-beta1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Allele-specific differential expression of a common adiponectin gene polymorphism related to obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Mutations in the adiponectin gene in lean and obese subjects from the Swedish obese subjects cohort

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Novel polymorphisms in the 5' region of the LEP gene: association with leptin levels and response to low-calorie diet in human obesity

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The insulin gene VNTR is associated with fasting insulin levels and development of juvenile obesity.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls.

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Heritability of plasma leptin levels: a twin study

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The -597 G-->A and -174 G-->C polymorphisms in the promoter of the IL-6 gene are associated with hyperandrogenism

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Genomic structure and mutations in adipose-specific gene, adiponectin

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Disturbed secretion of mutant adiponectin associated with the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

Genome-wide linkage analysis of serum adiponectin in the Pima Indian population

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

The Genetic Basis of Plasma Variation in Adiponectin, a Global Endophenotype for Obesity and the Metabolic Syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1262-3636%2807%2970112-X

7 January 2021

10.1016/S1262-3636(07)70112-X

Identifiers

DOI

1 reference

10 August 2017

1 reference