Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells (Q35824223)

10 August 2017

Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells (English)

1 reference

10 August 2017

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26034050%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Pamela M Odorizzi

1

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12 June 2020

Kristen E Pauken

2

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12 June 2020

Arlene Sharpe

4

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12 June 2020

E John Wherry

5

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12 June 2020

language of work or name

English

0 references

publication date

1 June 2015

1 reference

Journal of Experimental Medicine

10 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26034050%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

212

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12 June 2020

page(s)

1125-1137

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12 June 2020

issue

7

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The transcription factor FoxO1 sustains expression of the inhibitory receptor PD-1 and survival of antiviral CD8(+) T cells during chronic infection

12 June 2020

cites work

1 reference

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T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infection

27 July 2018

1 reference

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The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer.

27 July 2018

1 reference

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PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

27 July 2018

1 reference

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Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

27 July 2018

1 reference

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Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice.

27 July 2018

1 reference

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Selective effects of PD-1 on Akt and Ras pathways regulate molecular components of the cell cycle and inhibit T cell proliferation

27 July 2018

1 reference

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

27 July 2018

1 reference

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Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.

27 July 2018

1 reference

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Adoptive immunotherapy for cancer: harnessing the T cell response

27 July 2018

1 reference

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Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.

27 July 2018

1 reference

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Diagnostic and prognostic utility of PD-1 in B cell lymphomas

27 July 2018

1 reference

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Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

27 July 2018

1 reference

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Regulation of virus-specific CD4+ T cell function by multiple costimulatory receptors during chronic HIV infection

27 July 2018

1 reference

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A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

Redefining chronic viral infection

27 July 2018

1 reference

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PD-1 signaling in primary T cells

27 July 2018

1 reference

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Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection

27 July 2018

1 reference

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Enhancing SIV-specific immunity in vivo by PD-1 blockade

27 July 2018

1 reference

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Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

27 July 2018

1 reference

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Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade

27 July 2018

1 reference

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PD-1 and its ligands in tolerance and immunity

27 July 2018

1 reference

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Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

27 July 2018

1 reference

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PD-1 regulates self-reactive CD8+ T cell responses to antigen in lymph nodes and tissues

27 July 2018

1 reference

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Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection

27 July 2018

1 reference

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PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

27 July 2018

1 reference

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

27 July 2018

1 reference

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Restoring function in exhausted CD8 T cells during chronic viral infection

27 July 2018

1 reference

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CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

27 July 2018

1 reference

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PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells

27 July 2018

1 reference

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Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

27 July 2018

1 reference

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Lineage relationship and protective immunity of memory CD8 T cell subsets

27 July 2018

1 reference

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PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

27 July 2018

1 reference

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Factors influencing T-cell turnover in HIV-1-seropositive patients

27 July 2018

1 reference

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Viral immune evasion due to persistence of activated T cells without effector function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

The blockade of immune checkpoints in cancer immunotherapy

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

PDCD1 polymorphism amplifies the predisposing effect conferred by CTLA4 polymorphism in chronic hepatitis B virus infection

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

Association of PDCD1 polymorphisms with childhood-onset systemic lupus erythematosus

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493417

PDCD1: a tissue-specific susceptibility locus for inherited inflammatory disorders

24 September 2018

1 reference

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24 September 2018

Identifiers

DOI

10.1084/JEM.20142237

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26034050%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26034050%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference